Identification and validation of cigarette smoking-related genes in predicting prostate cancer development through bioinformatic analysis and experiments DOI Creative Commons

Duocheng Qian,

Xinan Wang,

Tengfei Lv

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 3, 2024

The morbidity and mortality rates of prostate cancer (PCa) are high among elderly men worldwide. Several factors, such as heredity, obesity, environment associated with the occurrence PCa. Cigarette smoking, which is also an important factor in development PCa, can lead to genetic alterations consequently promote PCa development. However, smoking-induced unclear. This study aimed identify potential smoking-related genes differentially expressed (DEGs) were identified using Gene Expression Omnibus (GEO) included lots datasets. DEGs subjected protein–protein interaction (PPI) network analysis hub genes. pathways these enriched identified. Cancer Genome Atlas (TCGA) dataset was used examine expression samples estimate their value predicting tumor progression prognosis. In total, 110 got from GSE68135 microarray data patients smoking or not 14 key PPI network. following seven altered TCGA patients: EWSR1, SRSF6, COL6A3, FBLN1, DCN, CYP2J2, PLA2G2A. CYP2J2 influenced progression. Additionally, EWSR1 disease-free survival. logistic regression model, exhibited highest risk scores, gene for We found one genes: truly upregulated clinical cells invasion proliferation. function involved

Язык: Английский

Prediction of Lymph Node Metastasis in Endometrial Cancer Based on Color Doppler Ultrasound Radiomics DOI
Xiaoling Liu,

Weihan Xiao,

Jing Qiao

и другие.

Academic Radiology, Год журнала: 2024, Номер 31(11), С. 4499 - 4508

Опубликована: Сен. 3, 2024

Язык: Английский

Процитировано

4

Treatments and cancer: implications for radiologists DOI Creative Commons
Vincenza Granata, Roberta Fusco, Sergio Venanzio Setola

и другие.

Frontiers in Immunology, Год журнала: 2025, Номер 16

Опубликована: Апрель 16, 2025

This review highlights the critical role of radiologists in personalized cancer treatment, focusing on evaluation treatment outcomes using imaging tools like Computed Tomography (CT), Magnetic Resonance Imaging (MRI), and Ultrasound. Radiologists assess effectiveness complications therapies such as chemotherapy, immunotherapy, ablative treatments. Understanding mechanisms consistent protocols are essential for accurate evaluation, especially managing complex cases liver cancer. Collaboration between oncologists is key to optimizing patient through precise assessments.

Язык: Английский

Процитировано

0

CLEAR guideline for radiomics: Early insights into current reporting practices endorsed by EuSoMII DOI
Burak Koçak, Andrea Ponsiglione, Arnaldo Stanzione

и другие.

European Journal of Radiology, Год журнала: 2024, Номер 181, С. 111788 - 111788

Опубликована: Окт. 14, 2024

Язык: Английский

Процитировано

1

Machine learning to predict radiomics models of classical trigeminal neuralgia response to percutaneous balloon compression treatment DOI Creative Commons
Ji Wu,

Chengjian Qin,

Yixuan Zhou

и другие.

Frontiers in Neurology, Год журнала: 2024, Номер 15

Опубликована: Ноя. 27, 2024

Classic trigeminal neuralgia (CTN) seriously affects patients' quality of life. Percutaneous balloon compression (PBC) is a surgical program for treating neuralgia. But some patients are ineffective or relapse after treatment. The aim to use machine learning construct clinical imaging models predict treatment (PBC).

Язык: Английский

Процитировано

0

Identification and validation of cigarette smoking-related genes in predicting prostate cancer development through bioinformatic analysis and experiments DOI Creative Commons

Duocheng Qian,

Xinan Wang,

Tengfei Lv

и другие.

Discover Oncology, Год журнала: 2024, Номер 15(1)

Опубликована: Дек. 3, 2024

The morbidity and mortality rates of prostate cancer (PCa) are high among elderly men worldwide. Several factors, such as heredity, obesity, environment associated with the occurrence PCa. Cigarette smoking, which is also an important factor in development PCa, can lead to genetic alterations consequently promote PCa development. However, smoking-induced unclear. This study aimed identify potential smoking-related genes differentially expressed (DEGs) were identified using Gene Expression Omnibus (GEO) included lots datasets. DEGs subjected protein–protein interaction (PPI) network analysis hub genes. pathways these enriched identified. Cancer Genome Atlas (TCGA) dataset was used examine expression samples estimate their value predicting tumor progression prognosis. In total, 110 got from GSE68135 microarray data patients smoking or not 14 key PPI network. following seven altered TCGA patients: EWSR1, SRSF6, COL6A3, FBLN1, DCN, CYP2J2, PLA2G2A. CYP2J2 influenced progression. Additionally, EWSR1 disease-free survival. logistic regression model, exhibited highest risk scores, gene for We found one genes: truly upregulated clinical cells invasion proliferation. function involved

Язык: Английский

Процитировано

0