The Nutritional and Health Potential of Alternative Grain Proteins: An In-Depth Comparison of Quinoa and Oat Proteins Isolates

Опубликована: Янв. 1, 2025

Язык: Английский

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Quinoa: Nutritional and phytochemical value, beneficial effects, and future applications

Applied Food Research, Год журнала: 2025, Номер unknown, С. 100766 - 100766

Опубликована: Фев. 1, 2025

Язык: Английский

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Preparation and analysis of quinoa active protein (QAP) and its mechanism of inhibiting Candida albicans from a transcriptome perspective

PeerJ, Год журнала: 2025, Номер 13, С. e18961 - e18961

Опубликована: Фев. 14, 2025

The globe cultivation and industrial production of quinoa have been steadily increasing. Nevertheless, the full potential quinoa’s nutritional economic benefits remains underexploited. This study investigates isolation purification active protein (QAP) through precipitation method using ammonium sulfate from a phosphate extraction solution. process involved gel filtration chromatography with Sephadex G-75 G-50 columns to obtain QAP fractions exhibiting inhibitory effects against Candida albicans ( C. ). A comprehensive series experiments was undertaken examine antifungal properties these fractions. Proteomic analysis employed elucidate composition proteins. Furthermore, activities succinate dehydrogenase, Ca 2+ -Mg -ATPase, catalase in following treatment were quantified an enzyme-linked immunosorbent assay. on cell morphology cultured Spider agar medium further investigated scanning electron microscopy (SEM). RNA-seq conducted investigate alterations gene expression cells subjected treatment. To functional significance changes, Gene Ontology Kyoto Encyclopedia Genes Genomes analyses performed. Quantitative real-time polymerase chain reaction subsequently validate observed changes expression. Our findings demonstrate that exhibits , minimum concentration 182 µg/mL. Through proteomic analysis, definitive set 18 proteins identified. At molecular level, genes associated hyphal development, wall membrane integrity, cellular respiration, energy metabolism found be enriched. Protein–protein interaction (PPI) revealed inhibit growth hyphae, compromise suppress oxidative phosphorylation. These disruptions collectively impair normal metabolic activities, thereby exerting effect .

Язык: Английский

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Therapeutic Potential of Plant‐Derived Peptides for Preventing or Treating Hypertension and Diabetes

Journal of Food Process Engineering, Год журнала: 2025, Номер 48(4)

Опубликована: Апрель 1, 2025

ABSTRACT Interest in plant‐derived bioactive peptides (BAPs) is increasing due to their potential therapeutic effects, low toxicity, abundance, scalability, and cost‐effectiveness. These can be obtained by hydrolyzing plant proteins from a diverse range of sources, including legumes, cereals, grains, oilseeds, tubers. This review discusses the benefits these on human health, addressing current challenges translating research into practical use. The structural aspects combating hypertension diabetes, encompassing structure–activity relationship studies, vitro vivo methodologies, absorption pathways are also discussed. Additionally, it explores molecular features, physicochemical properties, gastrointestinal fate, biological activities various peptides, reducing blood pressure sugar. hold promise as agents functional foods, supplements, pharmaceuticals, pending rigorous clinical trials ascertain efficacy safety. Successful could position innovative antihypertensive antidiabetic agents.

Язык: Английский

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Novel bioactive peptides from ginger rhizome: Integrating in silico and in vitro analysis with mechanistic insights through molecular docking

Food Chemistry, Год журнала: 2025, Номер unknown, С. 144432 - 144432

Опубликована: Апрель 1, 2025

Ginger (Zingiber officinale) is widely recognised for its functional benefits, primarily attributed to diverse phytochemicals. However, proteome remains largely unexplored. This study hypothesised that isolated peptides may exhibit different bioactivities or more targeted mechanisms of action and could be investigated at a molecular level. Proteins were enzymatically hydrolysed under five conditions, identified using LC-MS/MS. In silico screening suggested antioxidant, ACE-inhibitory, antibacterial properties, further assessed through docking in vitro validation. 41 potentially bioactive identified. assays confirmed these properties selected peptides, P1 (GSPVWIIPEPT), P2 (FASYPVKK), P3 (GPEKIFYDGPYL), P4 (IAISPSYPIK). Notably, exhibited potent mixed-type ACE-inhibition bacteriostatic effects. Molecular provided mechanistic insights into interactions. These findings highlight ginger as promising source while underscoring the need complement AI tools with vivo validations due observed discrepancies.

Язык: Английский

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Direct hydrolysis of einkorn whole grain flour proteins for the generation of bioactive peptides using various proteases

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 275, С. 133565 - 133565

Опубликована: Июнь 29, 2024

Язык: Английский

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Valorization of quinoa by-products and their potential applications

Cereal Research Communications, Год журнала: 2024, Номер unknown

Опубликована: Окт. 24, 2024

Язык: Английский

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Development of Bioactive Quinoa Protein Hydrolysate-based Emulsion Gels: Evaluation of Their Antioxidant and Rheological Properties

Food Biophysics, Год журнала: 2024, Номер 20(1)

Опубликована: Окт. 28, 2024

Язык: Английский

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Germination affects structural and techno-functional properties of proteins from quinoa seeds with increased realease of antioxidant peptides by gastrointestinal digestion

Food Chemistry, Год журнала: 2024, Номер 469, С. 142532 - 142532

Опубликована: Дек. 17, 2024

Язык: Английский

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