Exploring the link between inflammation and brain function after metabolic‐bariatric surgery: A year‐long fMRI study

Diabetes Obesity and Metabolism, Год журнала: 2025, Номер unknown

Опубликована: Янв. 16, 2025

Metabolic-bariatric surgery (MBS) transcends weight loss and offers wide-ranging health benefits, including positive effects on brain function. However, the mechanisms behind these remain unclear, particularly in context of significant postoperative changes inflammatory profile characteristic MBS. Understanding how inflammation influences function can enhance our decision-making patient eligibility for MBS create new opportunities to improve outcomes this popular treatment. To identify regions where spontaneous neural activity functional connectivity are linked with evolving following We investigated relationship between perioperative ratio interleukin (IL)-6 IL-10 both amplitude low-frequency fluctuation (ALFF) across 375 regions. examined 36 patients at three time points: 1 week before, 3 12 months after laparoscopic sleeve gastrectomy. Initially, IL-6/IL-10 increased during early period but then decreased levels lower than preoperative values year surgery. observed that ALFF four subcortical structures a rising declining ratio. Conversely, 16 cortical displayed opposite trend. Additionally, left insula bilateral medial prefrontal cortex Our study is first significantly Importantly, many discovered areas were previously shown be involved pathogenesis obesity or targets contemporary medical treatments. Consequently, findings offer valuable insights future research, especially potential therapeutic opportunities.

Язык: Английский

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A comparative study of cognitive function and reaction time in obese and non-obese adults

Neurological Research, Год журнала: 2025, Номер unknown, С. 1 - 10

Опубликована: Фев. 4, 2025

Objective Obesity may negatively affect the physical health and cognitive functions of individuals delay their reaction time to stimuli. However, association among obesity, functions, times is yet be fully elucidated. The aim this study was assess effect obesity on visual auditory in adults.

Язык: Английский

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The Relationship Between Physical Activity, Sedentary Time, and Cognitive Function Following Bariatric Surgery

Surgery for Obesity and Related Diseases, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

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Response to Dr. Buchwald

Obesity Surgery, Год журнала: 2024, Номер 34(5), С. 1947 - 1948

Опубликована: Апрель 8, 2024

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Bariatric Surgery Yields Substantial Improvements in Memory Function: Effect Size Evaluation

Obesity Surgery, Год журнала: 2024, Номер 34(6), С. 2256 - 2257

Опубликована: Апрель 15, 2024

Язык: Английский

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Response to Dr. Hung

Obesity Surgery, Год журнала: 2024, Номер 34(6), С. 2258 - 2258

Опубликована: Апрель 16, 2024

Язык: Английский

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Examining the Bidirectional Longitudinal Associations Between Body Mass Index and Episodic Memory Following Bariatric Surgery

Surgery for Obesity and Related Diseases, Год журнала: 2024, Номер 20(11), С. 1065 - 1071

Опубликована: Авг. 10, 2024

Язык: Английский

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Prospective Comparison of Mental Planning Ability in Sleeve Gastrectomy Patients and Non-operative Controls

Obesity Surgery, Год журнала: 2024, Номер 34(10), С. 3901 - 3904

Опубликована: Сен. 15, 2024

Язык: Английский

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