
Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Дек. 11, 2024
Язык: Английский
Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Дек. 11, 2024
Язык: Английский
Environmental Geochemistry and Health, Год журнала: 2025, Номер 47(4)
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
1Deleted Journal, Год журнала: 2024, Номер 21(1)
Опубликована: Сен. 9, 2024
Язык: Английский
Процитировано
3Toxics, Год журнала: 2025, Номер 13(5), С. 387 - 387
Опубликована: Май 12, 2025
Airborne micro and nanoplastics (MPs/NPs) are a growing issue due to their possible health hazards. Since the current bibliography lacks thorough evaluation, this review examines sources, environmental dynamics, impacts of airborne MPs/NPs. Through atmospheric transport processes, these neo-pollutants spread around world after being released, potentially settling in urban remote areas. This is first compare active passive aerosol sampling methods, microscopy, thermochemical, spectroscopy analytical techniques, with focus on limitations precisely quantifying micro-nanoscale plastic particles. It also draws attention potential toxicological effects inhaled MPs/NPs, which can lead oxidative stress, respiratory inflammation, other negative consequences. concludes by examining how MPs/NPs may worsen ecological impact serving as carriers hazardous chemicals microbial pollutants. Despite awareness, there still many unanswered questions, especially about long-term exposure conditions affect The aim was bring MP/NP promote development advanced monitoring systems, new multidisciplinary scientific field for study novel pollutants, global regulatory frameworks.
Язык: Английский
Процитировано
0Journal of Nanobiotechnology, Год журнала: 2025, Номер 23(1)
Опубликована: Май 28, 2025
Abstract Background Nanoplastics (NPs) are released into the environment through degradation of plastic objects, leading to human exposure. Due their small size, concerns have been raised about potential hazards respiratory tract, as ultrafine and nanoparticles known penetrate till alveolar regions lungs, potentially impairing functions. Thus, in present study, we used model polystyrene doped with fluorescent metal europium (PS-Eu) enhance understanding NPs hazard investigate adverse outcomes associated exposure lungs using (A549) bronchial (Calu-3) cell models grown 2D 3D submerged conditions or quasi air-liquid interface (ALI) (3D). Results Briefly, after in-dept physicochemical characterization particles, assessed impact on ROS production, viability (AlamarBlue lactate dehydrogenase assays) barrier integrity (lucifer yellow assay TEER measurement), finding no negative effects either model. However, cells, particles increased acidic organelle activity. Transmission electron microscopy Raman showed, both models, a dose- cell-dependent particle uptake PS-Eu accumulating numerous large endo-lysosomes, which, transwells-grown A549 often contained also lamellar bodies (LBs), organelles involved surfactants storage secretion. After extensively quantifying surfactant proteins (SP) pellet supernatant fractions treated observed significant reduction several members this family, including protein B, which is crucial for body formation surface tension regulation lungs. In quasi-ALI Calu-3 cultures instead, significantly upregulated interleukin 6 (IL-6) transforming growth factor beta β (TGF-β), zonula occludens 1 (ZO-1), mucin (MUC) 5B mRNA expressions causing moderate proinflammatory response. Conclusion Our results show that does not induce acute cytotoxicity these but affects cell-specific functions like surfactant, mucin, cytokine production. This underscores limitations relying solely standard tests assessment highlights importance investigating function-specific signaling pathways. To support researchers assessment, propose specific classes biomarkers test vitro lung models.
Язык: Английский
Процитировано
0EcoHealth, Год журнала: 2025, Номер unknown
Опубликована: Май 29, 2025
Язык: Английский
Процитировано
0MRS Energy & Sustainability, Год журнала: 2024, Номер 11(2), С. 343 - 368
Опубликована: Июль 22, 2024
Язык: Английский
Процитировано
2Research Square (Research Square), Год журнала: 2024, Номер unknown
Опубликована: Дек. 11, 2024
Язык: Английский
Процитировано
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