Critical Reviews in Microbiology,
Год журнала:
2025,
Номер
unknown, С. 1 - 23
Опубликована: Май 5, 2025
The
growing
demand
for
nanomedicine
and
its
potentially
diverse
biological
function
required
the
investigation
of
raw
materials
fabricating
nanomaterial.
Current
developments
have
emphasized
implementation
green
chemistry
to
develop
metal-oxide
metal
nanoparticles.
Endophytic
fungi
emerged
as
a
potential
reservoir
bioactive
compounds
exemplified
by
unique
structures
influential
antibacterial
properties.
Over
past
decade,
substantial
progress
has
been
achieved
in
uncovering
profiling
these
valuable
compounds.
These
endophytic
fungi-derived
chemicals
applications
various
Nanoparticle
synthesis
from
derived
fungi,
be
it
whole
extracts
or
pure
components,
owing
their
accessibility,
cost-effectiveness
fabrication,
material-tissue
compatibility,
modest
cytotoxicity
toward
higher
organism
cells.
Nanoparticles
utilized
treat
diseases,
including
those
caused
bacterial,
viral,
fungal
pathogens.
present
review
provides
comprehensive
discussion
mechanistic
insight
into
application
fungi-bioinspired
nanoparticles
therapeutic
agents
control
microbial
infection.
underlying
action
mechanism
involved
antimicrobial
also
discussed.
highlights
attributes
that
may
significantly
benefit
future
researchers
Green Processing and Synthesis,
Год журнала:
2025,
Номер
14(1)
Опубликована: Янв. 1, 2025
Abstract
In
this
work,
extracts
from
okra
fruit
are
used
to
create
zinc
oxide
nanoparticles
(ZnO
NPs)
in
an
economical
and
environmentally
friendly
manner.
During
the
synthesis
process,
(
Abelmoschus
esculentus
)
served
as
stabilizing
reducing
agents.
Various
analytical
methods
were
describe
final
nanoparticles.
The
outcomes
showed
that
produced
ZnO
NPs
primarily
exhibited
hexagonal
shapes,
with
sizes
ranging
20
27
nm
diameter.
cytotoxicity
study,
conducted
on
human
fibroblast
normal
HFB4
cell
lines,
indicated
IC
50
dose
was
227.8
μg·mL
−1
.
of
119.7
found
antitumor
effect
studies
using
breast
adenocarcinoma
Mcf-7
revealing
a
good
level
safety
for
NPs.
Compared
Gram-negative
infections,
have
significantly
higher
anti-bacterial
impact
against
Gram-positive
pathogens.
Molecular
docking
DNA
gyrase
A
subunit
Bacillus
subtilis
(PDB
ID:
4DDQ)
illustrated
interlocked
active
site
4DDQ
by
fitting
energy
value
−50.91
kcal·mol
through
three
classical
hydrogen
bonds
Asp96,
Thr220,
Ala221.
last
one
is
also
generated
marketing
tromethamine
drug
(TRS),
adding
some
TRS-like
character
NP
inhibitor.
Pharmaceutics,
Год журнала:
2025,
Номер
17(5), С. 591 - 591
Опубликована: Апрель 30, 2025
Background:
The
study
aimed
to
develop
a
sustainable
method
for
producing
myco-nanomaterials,
particularly
fluorescent
carbon
nanodots
(CNDs),
from
freeze-dried
Pleurotus
ostreatus
(Agaricomycetes)
mushroom
powder
via
pyrolysis.
goal
was
investigate
how
pyrolysis
conditions
affect
CND
characteristics
and
their
potential
antimicrobial
properties.
Mushroom
pyrolyzed
at
temperatures
ranging
150
240
°C.
resulting
products
were
analyzed
yield,
molecular
weight,
fluorescence
intensity,
estimated
concentration
in
relation
the
carbon-to-nitrogen
(C/N)
ratio.
Antibacterial
activity
tested
against
Escherichia
coli
Staphylococcus
epidermidis.
Product
yield
decreased
13.20%
°C
0.80%
Molecular
weight
peaked
200
(623.20
kDa),
while
maximum
intensity
(739.40
A.U.)
observed
210
A
strong
positive
correlation
(R2
=
0.72)
found
between
C/N
ratio
concentration.
Antimicrobial
testing
revealed
notable
inhibition
of
E.
coli,
associated
with
higher
content.
Pyrolyzed
P.
offers
promising,
eco-friendly
platform
luminescent,
carbonaceous
nanomaterials
antibacterial
potential.
These
non-purified,
myco-derived
may
contribute
green
nanotechnology
development
strategies.
Critical Reviews in Microbiology,
Год журнала:
2025,
Номер
unknown, С. 1 - 23
Опубликована: Май 5, 2025
The
growing
demand
for
nanomedicine
and
its
potentially
diverse
biological
function
required
the
investigation
of
raw
materials
fabricating
nanomaterial.
Current
developments
have
emphasized
implementation
green
chemistry
to
develop
metal-oxide
metal
nanoparticles.
Endophytic
fungi
emerged
as
a
potential
reservoir
bioactive
compounds
exemplified
by
unique
structures
influential
antibacterial
properties.
Over
past
decade,
substantial
progress
has
been
achieved
in
uncovering
profiling
these
valuable
compounds.
These
endophytic
fungi-derived
chemicals
applications
various
Nanoparticle
synthesis
from
derived
fungi,
be
it
whole
extracts
or
pure
components,
owing
their
accessibility,
cost-effectiveness
fabrication,
material-tissue
compatibility,
modest
cytotoxicity
toward
higher
organism
cells.
Nanoparticles
utilized
treat
diseases,
including
those
caused
bacterial,
viral,
fungal
pathogens.
present
review
provides
comprehensive
discussion
mechanistic
insight
into
application
fungi-bioinspired
nanoparticles
therapeutic
agents
control
microbial
infection.
underlying
action
mechanism
involved
antimicrobial
also
discussed.
highlights
attributes
that
may
significantly
benefit
future
researchers
