Abstract
Skin
health
and
protection
are
paramount
in
the
pursuit
of
well‐being
beauty.
In
this
study,
we
introduce
an
innovative
approach
to
develop
skin
protectant
agents
by
nanocomposites
derived
from
natural
sources,
involves
synthesis
selenium
nanoparticles
(SeNPs)
using
squash
plant
mucilage
(SqM),
their
integration
with
nano
chitosan
(NCht)
create
a
stable,
antimicrobial
efficacious
composite.
The
interactions
between
nanomaterials
were
proved
via
infra‐red
analysis
electron
microscopy.
SqM‐biosynthesized
SeNPs
had
11.47
nm
diameter.
Different
blends
nanocomposited
NCht
SqM/SeNPs;
NC‐2
nanocomposite
(with
equal
ratios
them)
mean
diameter
241.38
negatively
charged.
actions
produced
nanomaterials/nanocomposites
validated
against
pathogens,
Staphylococcus
aureus
Candida
albicans
,
assays
most
effectual
was
NC‐2;
loading
it
onto
cotton
textile
provided
potent
fabrics
toward
both
pathogens.
biosynthesis
SqM
nanocompositing
pioneering
powerful
complexes
control
either
through
direct
interaction
or
fabricating
hygienic
textiles.
PLoS ONE,
Год журнала:
2024,
Номер
19(11), С. e0314208 - e0314208
Опубликована: Ноя. 26, 2024
This
work
demonstrates
the
first
time
synthesis
of
selenium
nanoparticles
(Se
NPs)
stabilized
with
neonol.
The
method
was
optimized
using
a
multifactorial
experiment
three
input
parameters.
most
stable
sample
had
radius
15
nm
and
ζ-potential
-36.76
mV.
It
found
that
optimal
parameters
for
Se
NPs
neonol
are
following
concentration
values:
0.12
mol/L
selenic
acid,
0.095
0.95
ascorbic
acid.
Quantum
chemical
modeling
Se-neonol
molecular
complex
formation
showed
interaction
occurs
through
hydroxyl
group.
Difference
in
total
energy
molecule
is
more
than
2399
kcal/mol,
which
indicates
bond
between
energetically
advantageous.
all
samples
exhibit
stability
over
entire
pH
range
from
1.81
to
11.98,
particle
size
25–30
nm.
analysis
study
influence
ionic
force
cations
do
not
significantly
affect
radius,
but
anions
have
significant
effect,
increasing
average
hydrodynamic
up
2750
For
modification
NPs,
silk,
gauze,
wool,
cotton
cardboard
were
used.
Elemental
mapping
an
ambiguous
distribution
surface
fabric
material.
Assessment
potential
antibacterial
activity
modified
materials
revealed
inhibition
zones
Micrococcus
luteus
growth
12
16
mm
wool
cotton.
Notably,
intense
observed
treated
be
Cardboard
did
express
action
because
weak
cellulose
filaments
possible
microbial
digestion
xylan.
Abstract
Skin
health
and
protection
are
paramount
in
the
pursuit
of
well‐being
beauty.
In
this
study,
we
introduce
an
innovative
approach
to
develop
skin
protectant
agents
by
nanocomposites
derived
from
natural
sources,
involves
synthesis
selenium
nanoparticles
(SeNPs)
using
squash
plant
mucilage
(SqM),
their
integration
with
nano
chitosan
(NCht)
create
a
stable,
antimicrobial
efficacious
composite.
The
interactions
between
nanomaterials
were
proved
via
infra‐red
analysis
electron
microscopy.
SqM‐biosynthesized
SeNPs
had
11.47
nm
diameter.
Different
blends
nanocomposited
NCht
SqM/SeNPs;
NC‐2
nanocomposite
(with
equal
ratios
them)
mean
diameter
241.38
negatively
charged.
actions
produced
nanomaterials/nanocomposites
validated
against
pathogens,
Staphylococcus
aureus
Candida
albicans
,
assays
most
effectual
was
NC‐2;
loading
it
onto
cotton
textile
provided
potent
fabrics
toward
both
pathogens.
biosynthesis
SqM
nanocompositing
pioneering
powerful
complexes
control
either
through
direct
interaction
or
fabricating
hygienic
textiles.
