Mercury-Mediated Cardiovascular Toxicity: Mechanisms and Remedies

Cardiovascular Toxicology, Год журнала: 2025, Номер unknown

Опубликована: Фев. 4, 2025

Язык: Английский

Pathogenetic association of inflammation and hemostasis markers in the blood of patients with injuries of large joints

TRAUMA, Год журнала: 2025, Номер 26(1), С. 1 - 10

Опубликована: Март 7, 2025

Background. In patients with injuries of large joints, the activation inflammation causes risk thrombophilia. The prediction thrombotic complications and their prevention can improve quality treatment. purpose: to investigate data scientific medical literature on pathogenetic association between markers hemostasis in degenerative diseases post-traumatic joints. Materials methods. search for has been made PubMed database 10 years. Sixty works were selected. Results. A total 60 papers selected analysis. They recorded information about relationship mechanisms hypercoagulability trauma. specified are given this work. Conclusions. orthopedics traumatology, considerable attention is paid surgical treatment trauma, particular, Individuals trauma or surgery joints have a correlation biochemical common clinical inflammation, metabolism glycoproteins, proteoglycans collagen laboratory indicators hemostasis. case, significant damage formation vicious circle observed: decrease plasminogen content, which under action activators converted plasmin, trigger factor fibrinolytic system, that at same time activity acceleration dystrophic processes accumulation blood serum an excessive amount acute phase glycoproteins. addition, there increase plasma following coagulation markers: fibrinogen, soluble fibrin monomer complexes, D-dimers, inflammatory such as C-reactive protein, haptoglobin. From this, it follows postoperative requires timely monitoring markers, well measures prevent thrombophilia, including prehospital stage.

Язык: Английский

The Vaso-Occlusive Pain Crisis in Sickle Cell Patients: A Focus on Pathogenesis

Current Research in Translational Medicine, Год журнала: 2025, Номер unknown, С. 103512 - 103512

Опубликована: Март 1, 2025

Язык: Английский