Evaluation of Key Risk Factors Associated with Postoperative Complications in Colorectal Cancer Surgery DOI Creative Commons

Silviu Stefan Marginean,

Mihai Zurzu, Dragoş Garofil

и другие.

Journal of Mind and Medical Sciences, Год журнала: 2025, Номер 12(1), С. 22 - 22

Опубликована: Апрель 17, 2025

Background: Colorectal surgery remains a cornerstone in the management of colorectal cancer, yet postoperative complications continue to impact surgical outcomes. This study investigates key risk factors influencing morbidity, focusing on patient comorbidities, tumor characteristics, techniques, and anastomotic methods. Methods: A retrospective analysis was conducted 195 patients who underwent cancer between January 2021 December 2024 at Clinical Hospital Nephrology “Carol Davila”. Variables analyzed included demographics, staging, approach, complications. Statistical methods chi-square tests multivariate logistic regression (significance threshold: p < 0.05). Results: The overall complication rate 21%, with leakage observed 8.2% cases. Significant for morbidity cardiovascular disease (p = 0.001), chronic respiratory failure 0.003), renal 0.002). Laparoscopic had lower (7.1%) than open (28%) 0.003). Mechanical anastomosis showed rates manual suturing 0.009). Left-sided resections were associated higher right-sided procedures 0.013). Conclusions: Optimizing outcomes requires personalized perioperative strategies. approaches mechanical significantly reduce Further multicenter studies are needed confirm these findings enhance guidelines.

Язык: Английский

Evaluation of Key Risk Factors Associated with Postoperative Complications in Colorectal Cancer Surgery DOI Creative Commons

Silviu Stefan Marginean,

Mihai Zurzu, Dragoş Garofil

и другие.

Journal of Mind and Medical Sciences, Год журнала: 2025, Номер 12(1), С. 22 - 22

Опубликована: Апрель 17, 2025

Background: Colorectal surgery remains a cornerstone in the management of colorectal cancer, yet postoperative complications continue to impact surgical outcomes. This study investigates key risk factors influencing morbidity, focusing on patient comorbidities, tumor characteristics, techniques, and anastomotic methods. Methods: A retrospective analysis was conducted 195 patients who underwent cancer between January 2021 December 2024 at Clinical Hospital Nephrology “Carol Davila”. Variables analyzed included demographics, staging, approach, complications. Statistical methods chi-square tests multivariate logistic regression (significance threshold: p < 0.05). Results: The overall complication rate 21%, with leakage observed 8.2% cases. Significant for morbidity cardiovascular disease (p = 0.001), chronic respiratory failure 0.003), renal 0.002). Laparoscopic had lower (7.1%) than open (28%) 0.003). Mechanical anastomosis showed rates manual suturing 0.009). Left-sided resections were associated higher right-sided procedures 0.013). Conclusions: Optimizing outcomes requires personalized perioperative strategies. approaches mechanical significantly reduce Further multicenter studies are needed confirm these findings enhance guidelines.

Язык: Английский

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