Medicine, Год журнала: 2025, Номер 104(17), С. e42351 - e42351
Опубликована: Апрель 25, 2025
Monocytes play a pivotal role in the immune regulation of labor, contributing to processes like cervical ripening, uterine contractility, and initiation parturition. During monocytes are recruited cervix uterus, where they undergo activation release pro-inflammatory cytokines that help mediate contractions facilitate remodeling. However, dysregulation involving excessive or insufficient monocyte can contribute complications such as prolonged labor. The imbalance cytokine production dysfunction is thought be key factor delayed making critical targets for understanding managing labor abnormalities. Recent studies have explored potential monocyte-related biomarkers predictive tools identifying women at risk Monocyte subsets profiles, including markers CD14, CD16, interleukin-1β, tumor necrosis factor-alpha, interleukin-6, offer valuable insights into inflammatory status uterus. ability assess function levels may provide early indications dysregulation, allowing timely interventions prevent reduce complications. Advances diagnostic technologies, assays flow cytometry, improving our monitor activity during real time.
Язык: Английский