Consolidated knowledge-guided computational pipeline for therapeutic intervention against bacterial biofilms - a review DOI
Reetika Debroy, Sudha Ramaiah

Biofouling, Год журнала: 2023, Номер 39(9-10), С. 928 - 947

Опубликована: Ноя. 26, 2023

Biofilm-associated bacterial infections attributed to multifactorial antimicrobial resistance have caused worldwide challenges in formulating successful treatment strategies. In search of accelerated yet cost-effective therapeutics, several researchers opted for bioinformatics-based protocols systemize targeted therapies against biofilm-producing strains. The present review investigated the up-to-date computational databases and servers dedicated anti-biofilm research design/screen novel biofilm inhibitors (antimicrobial peptides/phytocompounds/synthetic compounds) predict their biofilm-inhibition efficacy. Scrutinizing contemporary

Язык: Английский

Consolidated knowledge-guided computational pipeline for therapeutic intervention against bacterial biofilms - a review DOI
Reetika Debroy, Sudha Ramaiah

Biofouling, Год журнала: 2023, Номер 39(9-10), С. 928 - 947

Опубликована: Ноя. 26, 2023

Biofilm-associated bacterial infections attributed to multifactorial antimicrobial resistance have caused worldwide challenges in formulating successful treatment strategies. In search of accelerated yet cost-effective therapeutics, several researchers opted for bioinformatics-based protocols systemize targeted therapies against biofilm-producing strains. The present review investigated the up-to-date computational databases and servers dedicated anti-biofilm research design/screen novel biofilm inhibitors (antimicrobial peptides/phytocompounds/synthetic compounds) predict their biofilm-inhibition efficacy. Scrutinizing contemporary

Язык: Английский

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