BIOMETALS IN NEURODEGENERATIVE DISEASES: THEIR BENEFICIAL AND DETRIMENTAL ROLES IN BRAIN HEALTH. DOI Open Access

TOBILOLA ODUNAYO AKINGBADE,

ELIJAH AYODELE OJO,

OPEYEMI PETER ADEBISI

и другие.

Greener Journal of Biomedical and Health Sciences, Год журнала: 2025, Номер 8(1), С. 16 - 27

Опубликована: Март 10, 2025

Biometals are essential to many physiological functions, including the normal functioning and development of brain. Notably, altered levels these biometals in body have been observed patients living with neurodegenerative conditions like Alzheimer’s, Huntington’s, Parkinson’s, Amyotrophic Lateral Sclerosis. This review will establish how can enter accumulate mechanisms for exhibiting neurotoxic effects. Correlations between level other non-essential metals existence diseases make them worthy study. Researchers looked toward biometal homeostasis as potential sources biomarkers, diagnostic breakthroughs, therapeutic solutions conditions. In addition, we explore benefit brain health, their role conditions, next frontiers biometal-based diagnostics therapy research.

Язык: Английский

BIOMETALS IN NEURODEGENERATIVE DISEASES: THEIR BENEFICIAL AND DETRIMENTAL ROLES IN BRAIN HEALTH. DOI Open Access

TOBILOLA ODUNAYO AKINGBADE,

ELIJAH AYODELE OJO,

OPEYEMI PETER ADEBISI

и другие.

Greener Journal of Biomedical and Health Sciences, Год журнала: 2025, Номер 8(1), С. 16 - 27

Опубликована: Март 10, 2025

Biometals are essential to many physiological functions, including the normal functioning and development of brain. Notably, altered levels these biometals in body have been observed patients living with neurodegenerative conditions like Alzheimer’s, Huntington’s, Parkinson’s, Amyotrophic Lateral Sclerosis. This review will establish how can enter accumulate mechanisms for exhibiting neurotoxic effects. Correlations between level other non-essential metals existence diseases make them worthy study. Researchers looked toward biometal homeostasis as potential sources biomarkers, diagnostic breakthroughs, therapeutic solutions conditions. In addition, we explore benefit brain health, their role conditions, next frontiers biometal-based diagnostics therapy research.

Язык: Английский

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