Green synthesis of pyrano[2,3-d]pyrimidine scaffolds in cetyltrimethylammonium bromide (CTAB) micellar media

Current Research in Green and Sustainable Chemistry, Год журнала: 2025, Номер unknown, С. 100456 - 100456

Опубликована: Май 1, 2025

Язык: Английский

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Synthesis of Dihydropyrano[2,3- c ]pyrazoles with Trifluoroethanol as a Reusable Promoting Medium: A Green Protocol

Organic Preparations and Procedures International, Год журнала: 2025, Номер unknown, С. 1 - 7

Опубликована: Май 15, 2025

Язык: Английский

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Halogenated dicyanobenzene-based photosensitizer (3DPAFIPN) as a thermally activated delayed fluorescence (TADF) used in gram-scale photosynthesis 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives via a consecutive visible-light-induced electron-transfer pathway

Frontiers in Chemistry, Год журнала: 2024, Номер 12

Опубликована: Март 1, 2024

Background: Organic dyes often have shorter lifetimes in the excited state, which is a major obstacle to development of effective photoredox methods. The scientific community has shown great deal interest certain class organic chromophores because their unique characteristics and effectiveness. One characteristic molecules under research thermally activated delayed fluorescence (TADF), only observed with tiny energy gap (often less than 0.2 eV) between lowest two states, i.e., singlet state (S 1 ) triplet (T ). extended states arising from TADF simplicity redox potentials may be altered make isophthalonitrile family an attractive option for photocatalyst applications. Methods: Biginelli reaction β -ketoesters, arylaldehydes, urea/thiourea been used build sustainable technique production 3,4-dihydropyrimidin-2-(1 H )-one/thione derivatives. In present study, green radical synthesis approach this compounds addressed depth. As photocatalyst, new halogenated dicyanobenzene-based photosensitizer was employed study. renewable source by blue LED, it dissolved ethanol, at room temperature air atmosphere. primary objective employ novel donor-acceptor (D-A) based on cyanoarene that affordable, easily available, innovative. Findings: 3DPAFIPN [2,4,6-tris(diphenylamino)-5-fluoroisophthalonitrile] induces single-electron transfer (SET) response visible light, offering straightforward, eco-friendly, highly efficient process. Additionally, we determined derivatives turnover frequency (TOF) number (TON). It also demonstrated gram-scale cyclization workable method industrial purposes.

Язык: Английский

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Aqueous TPGS-750-M-mediated synthesis of pyrano[2,3-c]-pyrazoles: a sustainable and efficient approach

Research on Chemical Intermediates, Год журнала: 2024, Номер 50(6), С. 2827 - 2840

Опубликована: Апрель 23, 2024

Abstract The article describes a green and efficient synthesis method for pyrano[2,3-c]-pyrazoles, employing DL-alpha-tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) as biodegradable surfactant in water. utilization of water reaction medium TPGS-750-M obviates the necessity organic solvents, thereby enhancing environmental sustainability synthesis. compounds synthesized using this novel was characterized various spectroscopic techniques, including 1 H-NMR, 13 C-NMR, mass spectrometry. Graphical abstract

Язык: Английский

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Recent Advances in Catalytic Approaches for Pyrano[2,3‐c]Pyrazole Synthesis: Green and Sustainable Perspectives

ChemistrySelect, Год журнала: 2025, Номер 10(12)

Опубликована: Март 1, 2025

Abstract This review provides a detailed look at the methods used to create pyrano[2,3‐c]pyrazole derivatives over past ten years, with focus on various catalytic techniques. The highlights progress in green chemistry, showing how catalysts such as homogeneous, heterogeneous, and nanoparticle types have been used. It also discusses new approaches like microwave‐assisted catalyst‐free synthesis. evaluates effectiveness of different based reaction efficiency, yield, sustainability. Furthermore, it explores eco‐friendly options bio‐catalysts ionic liquid catalysts, which offer scalable environmentally‐friendly for producing these important compounds. Pyrano[2,3‐c]pyrazoles were chosen their significant potential pharmaceuticals industry. emphasizes sustainable are becoming more modern particularly due reusability lower environmental impact, making them ideal industrial applications.

Язык: Английский

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Recent Advancement of 1,2,3,5‐Tetrakis(Carbazol‐9‐yl)‐4,6‐Dicyanobenzene (4‐CzIPN) in Photocatalyzed Synthesis of Heterocyclic Compounds

ChemistrySelect, Год журнала: 2025, Номер 10(17)

Опубликована: Май 1, 2025

Abstract 4‐CzIPN is a traditional electron donor and acceptor fluorophore that uses carbazolyl as an donating dicyanobenzene withdrawing source. Its broad redox potential, high chemical resistance wide applicability makes it unique metal‐free photocatalyst. This study summarizes the recent development of photoredox catalyst for variety heterocyclic construction over last four years (2021‐2024).

Язык: Английский

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9-mesityl-10-methylacridinium perchlorate (Mes-Acr-Me+ClO4−) as a novel metal-free donor–acceptor (D–A) photocatalyst: visible-light-induced access to tetrahydrobenzo[b]pyran scaffolds through a single-electron transfer (SET) pathway

Research on Chemical Intermediates, Год журнала: 2024, Номер 50(7), С. 2993 - 3007

Опубликована: Май 20, 2024

Язык: Английский

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1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) as a reusable promoting medium for the catalyst-free and green synthesis of dihydropyrano[2,3-c]pyrazole scaffolds

Results in Chemistry, Год журнала: 2024, Номер 9, С. 101629 - 101629

Опубликована: Июль 1, 2024

A manufactured protocol that is both helpful and free of catalyst has been presented for the production dihydropyrano[2,3-c]pyrazole frameworks in polyfluorinated alcohol as a reusable promoting medium. All reactions are completed quickly, products obtained astounding yields. Notably, convenient approach remarkable yields, avoids use hazardous solvents or reagents, simple to operate, only requires one pot. The 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) was extremely stable could be repeated four times without significant basic alteration action, making it ideal large-scale organic production.

Язык: Английский

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Acridine Yellow G: A Photo-induced Electron Transfer Photocatalyst for the Radical Synthesis of Pyrano[2,3- d ]pyrimidines in an Aqueous Medium

Organic Preparations and Procedures International, Год журнала: 2024, Номер 56(5), С. 419 - 428

Опубликована: Фев. 7, 2024

Язык: Английский

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Green Synthetic Approach for Catalyst-free Synthesis of 2-Amino-4 H -chromenes Promoted by Glycerol as a Reusable Medium

Organic Preparations and Procedures International, Год журнала: 2024, Номер unknown, С. 1 - 7

Опубликована: Июнь 5, 2024

Язык: Английский

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