Hemostatic abnormalities for predicting and management of disease severity in COVID-19 affected patients: Review DOI Creative Commons
Kovuri Umadevi,

Ruchira Clementina,

Dola Sundeep

и другие.

Aspects of Molecular Medicine, Год журнала: 2024, Номер 3, С. 100043 - 100043

Опубликована: Май 5, 2024

The recent Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic has posed significant challenges to global healthcare, with a myriad of impacts on the human body, particularly noted in hemostatic abnormalities observed COVID-19 patients. These have been linked an increased risk serious thrombotic events like deep vein thrombosis, pulmonary embolism, and stroke. Unlike existing literature, this comprehensive review delves into long-term implications these abnormalities, providing invaluable guidance for ongoing patient care as we move post-pandemic era. We cover entire spectrum including elevated levels aPTT, D-dimer, PT, ferritin, INR, fibrinogen, fibrin, FDP, all which create complex clinical scenario necessitating vigilant monitoring targeted therapeutic interventions. With focus heightened complications, underscore importance timely anticoagulant therapy other necessary interventions, tailored patient's unique presentation. This stands critical resource clinicians, hematologists, healthcare providers, equipping them navigate complexities both acute settings, ensuring optimal outcomes. As collectively lasting impact pandemic, in-depth analysis becomes indispensable tool advancing our understanding management COVID-19.

Язык: Английский

Enhanced ballistic and mechanical performance of aluminum nickel phosphorus bronze composites reinforced with TiCN and Y₂O₃ for armored vehicles DOI Creative Commons
Arif Rahman, Dola Sundeep, C. Chandrasekhara Sastry

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Март 25, 2025

In response to emerging military tactics and technological advancements, this research investigates the ballistic mechanical properties of cutting-edge defense-grade aluminum nickel phosphorus bronze (Al-NPB) metal matrix composites (MMCs), enhanced with 2, 4, 6 weight percent titanium carbonitride (TiCN) coated yttrium oxide (Y₂O₃). The Y₂O₃ nanoparticles were initially synthesized through milling, followed by further milling TiCN produce + (TY) nanopowders, which subsequently integrated into Al-NPB via stir-casting. Comprehensive characterization using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) confirmed successful formation nanocomposite MMC. Mechanical testing, encompassing tensile, impact, compression evaluations, revealed that a 4 filler loading yielded optimal strength. Additionally, MMCs rigorously assessed for corrosion resistance morphological attributes. Ballistic testing promising outcomes, underscoring potential applicability these in armored fighting vehicles (AFVs). This study introduces novel MMC could significantly enhance performance durability AFVs challenging operational environments, contributing advancement defense technologies.

Язык: Английский

Процитировано

0
Hemostatic abnormalities for predicting and management of disease severity in COVID-19 affected patients: Review DOI Creative Commons
Kovuri Umadevi,

Ruchira Clementina,

Dola Sundeep

и другие.

Aspects of Molecular Medicine, Год журнала: 2024, Номер 3, С. 100043 - 100043

Опубликована: Май 5, 2024

The recent Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pandemic has posed significant challenges to global healthcare, with a myriad of impacts on the human body, particularly noted in hemostatic abnormalities observed COVID-19 patients. These have been linked an increased risk serious thrombotic events like deep vein thrombosis, pulmonary embolism, and stroke. Unlike existing literature, this comprehensive review delves into long-term implications these abnormalities, providing invaluable guidance for ongoing patient care as we move post-pandemic era. We cover entire spectrum including elevated levels aPTT, D-dimer, PT, ferritin, INR, fibrinogen, fibrin, FDP, all which create complex clinical scenario necessitating vigilant monitoring targeted therapeutic interventions. With focus heightened complications, underscore importance timely anticoagulant therapy other necessary interventions, tailored patient's unique presentation. This stands critical resource clinicians, hematologists, healthcare providers, equipping them navigate complexities both acute settings, ensuring optimal outcomes. As collectively lasting impact pandemic, in-depth analysis becomes indispensable tool advancing our understanding management COVID-19.

Язык: Английский

Процитировано

0