Exploring DMT: Endogenous Role and Therapeutic Potential

Neuropharmacology, Год журнала: 2025, Номер unknown, С. 110314 - 110314

Опубликована: Янв. 1, 2025

Язык: Английский

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Breathwork-induced psychedelic experiences modulate neural dynamics

Cerebral Cortex, Год журнала: 2024, Номер 34(8)

Опубликована: Авг. 1, 2024

Abstract Breathwork is an understudied school of practices involving intentional respiratory modulation to induce altered state consciousness (ASC). We simultaneously investigate the phenomenological and neural dynamics breathwork by combining Temporal Experience Tracing, a quantitative methodology that preserves temporal subjective experience, with low-density portable EEG devices. Fourteen novice participants completed course up 28 sessions—of 20, 40, or 60 min—in days, yielding neurophenomenological dataset 301 sessions. Using hypothesis-driven data-driven approaches, we found “psychedelic-like” experiences were associated increased Lempel-Ziv complexity during breathwork. Exploratory analyses showed aperiodic exponent power spectral density—but not oscillatory alpha power—yielded similar associations. Non-linear features, like exponent, neurally map both multidimensional composite positive experiences, aspects psychedelic-like experience states such as high bliss.

Язык: Английский

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Effect of 40 continuous connected breathing on electroencephalogram and heart rate variability of healthy volunteers

Indian Journal of Physiology and Pharmacology, Год журнала: 2025, Номер 0, С. 1 - 9

Опубликована: Фев. 3, 2025

Objectives: Continuous connected breathing (CCB) is a high-frequency technique without breath retention. This study examines changes in electroencephalogram (EEG) band power and heart rate variability (HRV) before, during after breathwork intervention of 3 rounds 40 CCB versus normal healthy volunteers. Materials Methods: Thirty-three volunteers, aged between 19 23 years, participated the ( n = 15; female 7; mean age 21.5 years) group, while control group consisted 18 individuals 18; male 11; 19.6 years). After acquiring baseline measures, engaged practice online for 10 days, continued with their usual activities. EEG HRV signals were recorded both groups days. Post-intervention, practised breathwork, breathed normally signal acquisition. was 1-min durations at five different time events (1 st , 4 th 5 7 min) according to protocol. continuously entire min, readings corresponding recording intervals analysed. acquired using an Enobio-8 cap dry electrodes pre-frontal (FP1 FP2), temporal (T7 T8), central (C3 C4) occipital (O1 O2) regions. data from Polar H7/H10 chest strap sensors through Bluetooth Elite app on android phone later processed Kubios software. MATLAB software extract delta (0– 3.5Hz), theta (4–7 Hz), alpha (8–13 beta (14–29 Hz) gamma frequencies (30–50 Hz). The arranged as before-after statistically analysed within between-group t -tests significance means. Results: There overall quantitative change −2 units −0.03 group. A significant decrease found (−2.27), (−1.7), (−1.8) (−2.27) brain waves (FP1, FP8), (T7, T8) (O1, regions compared before increase (+2.8) higher left right hemisphere. Bilateral average ranged −1.6 −2.6 −0.1 +4.9 parameters reduced but significance. improved though not significant. Conclusion: days breathworks (3 rounds) min/day may reduce delta, theta, waves. It help maintain autonomic balance recovery phase initial breathwork. Further studies are recommended test consistency outcomes.

Язык: Английский

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Electroencephalograph (EEG) based classification of mental arithmetic using explainable machine learning

Journal of Applied Biomedicine, Год журнала: 2025, Номер 45(2), С. 154 - 169

Опубликована: Фев. 26, 2025

Язык: Английский

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Decreased CO2 saturation during circular breathwork supports emergence of altered states of consciousness

Communications Psychology, Год журнала: 2025, Номер 3(1)

Опубликована: Апрель 13, 2025

Altered states of consciousness (ASCs), induced e.g. during psychedelic-assisted therapy, show potential to treat prevalent mental health disorders like depression and posttraumatic stress disorder. However, access such treatments is restricted by legal, medical, financial barriers. Circular breathwork may present a non-pharmacological hence more accessible alternative engage similar therapeutic processes. Scientific studies are only just emerging its physiological psychological mechanisms largely unknown. Here, we track experiential dynamics throughout session, comparing two forms breathwork: Holotropic Conscious-Connected breathwork. We that reduction in end-tidal CO2 pressure due deliberate hyperventilation significantly correlated ASC onset (r = -0.46; p < 0.001). Based on standard questionnaires (MEQ-30 11-DASC), the ASCs evoked resembled those produced psychedelics across several domains as ego dissolution, their depth predicted follow-on effects, including improved well-being reduced depressive symptoms. Further analysis showed different approaches highly outcomes. Our findings identify boundary conditions for arise context, shedding light functional well psychotherapeutic tool.

Язык: Английский

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‘Mind-Revealing’ Psychedelic States: Psychological Processes in Subjective Experiences That Drive Positive Change

Psychoactives, Год журнала: 2024, Номер 3(3), С. 411 - 436

Опубликована: Сен. 18, 2024

This narrative review explores the utilization of psychedelic states in therapeutic contexts, deliberately shifting focus from substances back to experiential phenomena which they induce, alignment with original meaning term “mind-manifesting”. provides an overview various used modern settings and ritualistic indigenous as well non-pharmacological methods that can arguably induce states, including breathwork, meditation, sensory deprivation. While occurrence mystical experiences seems be strongest predictor positive outcomes, literature this field yields several other psychological processes, such awe, perspective shifts, insight, emotional breakthrough, acceptance, re-experiencing memories, certain aspects challenging experiences, are significantly associated change. Additionally, we discuss detail experience-related changes metaphysical self-related beliefs their respective contributions observed outcomes. We conclude a purely medical neurobiological on health is reductive should not overshadow significance phenomenological understanding treating issues manifest subjective realities human individuals.

Язык: Английский

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Breathwork-Induced Psychedelic Experiences Modulate Neural Dynamics

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Фев. 22, 2024

Abstract Breathwork is a term for an understudied school of practices that involve the intentional modulation respiration to induce altered state consciousness (ASC). We map here neural dynamics mental content during breathwork, using neurophenomenological approach by combining Temporal Experience Tracing, quantitative phenomenological methodology preserves temporal subjective experience, with low-density portable EEG devices every session. Fourteen novice participants completed series up 28 breathwork sessions - 20, 40 or 60 minutes in days, yielding dataset 301 sessions. Using hypothesis-driven and data-driven approaches, we found positive ‘psychedelic-like’ experiences occurred within were associated increased Lempel-Ziv complexity. Further, exploratory analyses showed aperiodic exponent power spectral density (PSD) but not oscillatory alpha was also these psychedelic-like substates. demonstrate strength this framework, maximising concurrent data acquisition brain activity multiple experiential dimensions. Non-linear aspects dynamics, like complexity PSD, neurally both complex composite experiences, experience states such as high bliss.

Язык: Английский

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Breathing exercises influence on psychoemotional state in different age groups

Scientific Journal of National Pedagogical Dragomanov University Series 15 Scientific and pedagogical problems of physical culture (physical culture and sports), Год журнала: 2024, Номер 3K(176), С. 144 - 149

Опубликована: Март 18, 2024

The research aims to investigate the potential of employing breathing techniques restore psychological and emotional well-being individuals who have been subjected prolonged exposure stress-inducing factors. recognition public's demand for accessible mental health resources has led identification necessity assess efficacy these interventions. Simultaneously, matter age disparities in implementation this approach is exposed. Due widespread adoption practices Ukraine, it imperative provide recommendations that are grounded empirical evidence. Methodology. sample consisted 514 individuals, categorised into four primary cohorts: high schoolers, young, young adults, late adults. groups were subdivided equivalent subgroups based on their involvement practice. authors utilised POM-15 scale BBC Modified Scale Subjective Well-being evaluate psycho-emotional parameters. statistical analysis employed multivariate variance (MANOVA). Novelty. This study validates beneficial impact breathwork health. Furthermore, suitability methods various cohorts assessed, taking account consistent lack variation outcomes across different groups. importance selecting specific tailored issues target audience emphasised. Conclusion. notable disparity levels between engage regular exercises those do not, suggests activity enhance one's state. No discrepancies detected among examined cohorts. Breathing regarded as a cost-effective non-intrusive tending

Язык: Английский

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Non-ordinary states of consciousness evoked by breathwork correlate with improved heart-rate variability

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 21, 2024

High ventilation breathwork is a breathing practice that involves deep, accelerated over prolonged duration (> 15 minutes). This basic underpins wide range of traditions, from Pranayama to Holotropic and Conscious-Connected breathwork. Anecdotal reports suggest it can benefit physical mental health, often by evoking altered states consciousness. However, scientific research on still in its infancy. study examines the physiological experiential effects Breathwork (CCB). Specifically, we characterize subjective experiences using Natural Language Processing analyses semi-structured phenomenological interviews, relate them changes Heart-Rate Variability (HRV). Finally, disentangle technique itself context effects, tested whether presence evocative music modified impact session. Our findings indicate CCB consistently triggers consciousness, accompanied increased emotional intensity decreased HRV during session, but baseline following increase was larger for subjects who experienced wider emotions not predicted peri-session HRV. suggests post-session improvements might be product catharsis rather than purely hormesis. none these significantly modulated music, indicating they largely rely itself.

Язык: Английский

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Effects of brief remote high ventilation breathwork with retention on mental health and wellbeing: A randomised placebo-controlled trial

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Апрель 22, 2024

High ventilation breathwork with retention (HVBR) might be beneficial for mental/physical health and has been growing in popularity over the past decade. However, little research investigated potential therapeutic effects of brief, remotely delivered HVBR tolerability profile this technique. This study (NCT06064474) was largest blinded randomised-controlled trial on to date which 200 young, healthy adults balanced gender were randomly allocated blocks 2 by remote software 3 weeks 20 min daily (fast breathing long breath holds) or a placebo comparator (15 breaths/min short holds). The concealed as ‘fast breathwork’ wherein both intervention masked, only ~ 40% guessed their group assignment no difference accuracy between groups. Both groups reported analogous credibility expectancy benefit, subjective adherence, positive sentiment, along short- long-term tolerability. At post-intervention (primary timepoint) stress level outcome), we found significant x time interaction, F(1,180) = 1.98, p 0.16, η_p² 0.01, d 0.21), nor main effect group, (F 0.35, 0.55, < 0.01) but did find time, 13.0, 0.07). There improvement pre-post-intervention groups, however there such across In addition at follow-up, interactions secondary trait outcomes anxiety, depression, mental wellbeing, sleep-related impairment. also case state negative affect after first session post-intervention. Brief therefore may not more efficacious improving than well-designed active otherwise healthy, young adults. Funders: Ryoichi Sasakawa Young Leaders Fellowship Fund, PsyDAO.

Язык: Английский

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