Waste and Biomass Valorization,
Год журнала:
2024,
Номер
unknown
Опубликована: Июль 18, 2024
Abstract
The
purpose
of
this
work
was
to
prepare
silver
nanoparticles
from
weedy
plant
material.
extracts
were
prepared
fresh
and
dried
Reynoutria
leaves
at
100
°C,
21
°C.
Organic
substances
(e.g.
flavonoids)
in
the
extract
bohemica
served
as
reducing
agent
preparation
Ag
0
AgNO
3
precursor.
Silver
by
adding
1
mM
tempered
70
°C
for
24
h.
color
change
during
formation
monitored
using
UV-vis
spectra,
where
maximum
absorbance
detected
420
nm.
size
stability
particles
determined
Dynamic
Light
Scattering
method
40–50
nm,
their
zeta
potential
about
−
23
mV.
Finally,
cold
route
biosynthesis
appears
be
a
new
energetically
beneficial
way
preparing
nanoparticles.
laboratory
temperature
AgNPs
also
synthesized
.
shift
absorption
450
nm
observed,
with
particle
85
–
time-consuming
(72
h),
but
without
energy
costs
utilizing
an
invasive
-
that
is,
truly
green
synthesis
This
paper
introduces
novel
approach
widely
distributed
nanoparticles,
developing
cost-effective
energy-saving
operates
room
heating.
Graphical
Materials Today Bio,
Год журнала:
2024,
Номер
30, С. 101377 - 101377
Опубликована: Дек. 5, 2024
We
explored
the
feasibility
of
a
self-assembled
chitosan
nanocomposite
incorporating
cerium
oxide/nanoceria
and
superparamagnetic
iron
oxide
nanoparticles
(Chit-IOCO
NPs),
conjugated
with
methotrexate
(MTX)
Cy5
dye,
as
an
integrated
cancer
theranostic
nanosystem
(Chit-IOCO-MTX-Cy5).
In
this
system,
nanoceria
serves
anti-cancer
agent,
while
function
negative
contrast
agent
for
MR
imaging.
This
dual
metal
is
MTX
which
structural
analogue
folate,
serving
both
targeting
mechanism
folate
receptors
on
cells
chemotherapeutic
drug.
Chit-IOCO-MTX-Cy5
exhibited
exceptional
in
T2
T2∗-weighted
MRI,
achieving
high
relaxivity
409.5
mM⁻
Macromol—A Journal of Macromolecular Research,
Год журнала:
2025,
Номер
5(1), С. 13 - 13
Опубликована: Март 18, 2025
Members
of
the
Cinnamomum
genus
have
been
utilized
for
medicinal
treatment
millennia.
In
recent
years,
particular
attention
has
given
to
bioactive
metabolites
involved
in
properties
natural
products
and
their
extracts.
Cinnamon
is
particularly
interesting
due
presence
both
terpenoid
polyphenol
moieties,
which
extensively
studied
applications
a
wide
range
conditions,
from
bacterial
infection,
obesity
diabetes
cancer
cardiovascular
pathologies.
Here,
we
reviewed
some
cinnamon
its
derivatives
cinnamic
acid,
trans-cinnamaldehyde
beta-caryophyllene.
addition,
advancements
application
cancer,
focusing
on
gynecological
breast
cancers,
present
unique
challenges
late
diagnosis,
discussed.
Current
further
enhance
delivery
through
nanoencapsulation
nanoparticulate
strategies
as
well
development
novel
conjugates
hybrids
are
also
Additionally,
use
adjuvants
with
chemotherapeutics
that
can
work
synergistically
was
touched
upon.
Overall,
biotechnological
innovations
enhanced
such
may
pave
path
therapeutic
fewer
side
effects
higher
potency.
represents
valuable
source
developing
anticancer
materials
warrant
additional
research
potential
interventions
or
combination
treatments.
PLoS ONE,
Год журнала:
2025,
Номер
20(6), С. e0324445 - e0324445
Опубликована: Июнь 5, 2025
This
study
reports
the
multifunctional
potential
of
gold
nanoparticles
(AuNPs)
biosynthesized
by
using
Salvia
splendens
leaf
extract
(SSLE).
The
AuNPs
were
characterized
UV–Visible
spectroscopy,
transmission
electron
microscopy
(TEM),
and
dynamic
light
scattering,
followed
assessment
their
anti-cancer,
anti-oxidant,
anti-inflammatory
anti-bacterial
potentials.
SSLE-AuNPs
showed
a
characteristic
absorbance
peak
at
559
nm
that
corresponds
to
surface
plasmon
resonance
(SPR)
band
AuNPs.
zeta
was
estimated
be
‒
21
±
1.9
mV,
TEM
analysis
confirmed
particles
spherical
with
an
average
size
94.8
5.1
nm.
exhibited
dose-dependent
antioxidant
activity,
IC50
values
218.5
4.2
µg/mL
(DPPH)
185.3
3.7
(ABTS),
compared
ascorbic
acid
(32.1
1.8
28.6
1.5
µg/mL,
respectively.
In
addition,
exerted
potent
effect
against
Staphylococcus
aureus
(MIC
50
68
2.1
μg/mL)
Klebsiella
pneumoniae
82
2.3
μg/mL),
which
comparable
standard
antibacterial
agent,
tetracycline.
Moreover,
induced
significant
reduction
in
cellular
viability
A549
cells
concentrations
100,
200
400
μg/mL,
respectively
(p
<
0.001).
Such
cytotoxic
accompanied
considerable
instigation
nuclear
fragmentation
condensation,
caspase
activation,
ROS
generation
cells.
Furthermore,
vitro
studies
highlighted
on
murine
alveolar
macrophages
(J774A.1)
via
deflating
inflammatory
mediators
such
as
proinflammatory
cytokines.
To
sum
up,
present
findings
have
substantiated
antioxidant,
antibacterial,
anticancer
antiphlogistic
properties
SSLE-AuNPs,
paving
way
for
subsequent
investigations
into
green
synthesized
nano-formulations.
