Ageing and Neurodegenerative Diseases, Год журнала: 2024, Номер 4(4)

Опубликована: Дек. 13, 2024

The cerebellum has long been associated with motor control. However, its role in cognitive functions attracted increasing attention recently. uniformity of cerebellar internal structure seems at odds involvement such diverse functions. Nonetheless, diseases as ataxia, there is a comorbidity and impairments, raising essential questions about how to what extent the participates This review begins by tracing historical development research, suggesting that connections between cerebral cortex, basal ganglia, other subcortical nuclei form basis for cerebellum’s regulating We then delve into language, reward-based learning, working memory, spatial cognition. Additionally, we summarize changes observed Alzheimer’s disease (AD), Parkinson’s (PD), ataxias their impact on By discussing mechanism cognition physiology pathology from aspects function, aim shed light promising new therapeutic targets related impairment.

Язык: Английский