Case report: unprecedented case of infantile cerebral infarction following COVID-19 and favorable outcome DOI Creative Commons

Shuhong Zheng,

Hairui Chen,

Weiwei Xu

и другие.

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Март 25, 2024

The 2019 novel coronavirus, SARS-CoV-2, was highly prevalent in China as of December 2022, causing a range symptoms, predominantly affecting the respiratory tract. While SARS-CoV-2 infection children is generally mild, severe cases, especially infants, are rare. We present case previously healthy 7-month-old infant who developed cerebral infarction and coagulation dysfunction three days after COVID-19 onset. Clinically, had weakness left limbs pinpoint bleeding spots. A cranial magnetic resonance imaging showed ischemic strokes right basal ganglia thalamus. Laboratory tests indicated thrombocytopenia dysfunction. Inflammatory cytokines like interleukin-10 were elevated, with increased CD3 + , CD4 CD8 T lymphocytes but decreased - CD16 CD56 natural killer cells. Treatment included mannitol, dexamethasone, oral aspirin, vitamins B1 B6 for reducing intracranial pressure, antiinflammation, anticoagulation, nerve support, respectively. During recovery phase, rehabilitation therapy focused on strength training, fine motor skills, massage therapy. gradually improved successfully recovered. rare, such cases can lead to complications. These combined efforts instrumental achieving significant functional patient, demonstrating that even instances pediatric due COVID-19, positive outcomes attainable early comprehensive medical response.

Язык: Английский

Characteristics of unintentional childhood injury during COVID-19: a single-center comparative study DOI Open Access

Qingti Tan,

Tao Wang, Nuo Xu

и другие.

Translational Pediatrics, Год журнала: 2023, Номер 12(3), С. 405 - 416

Опубликована: Март 1, 2023

Background: There are many articles related to child injuries during the coronavirus disease of 2019 in other countries, but only few studies this field China.This study analyzes clinical characteristics unintentional childhood injury pandemic, provide reference for prevention context pandemic.Methods: A comparative was performed on medical data 2,497 children with who were hospitalized at Chengdu Women's and Children's Central Hospital between 1 January, 2018 31 May, 2021.The period divided into 2 periods, before pandemic (1 2019), 2020 2021).The number age distribution compared.Group differences examined using Mann-Whitney U continuous variables Chi-squared or Kruskal-Wallis tests categorical variables.Results: significant age, accident location, hospitalization days, expenses (P<0.05).During children's increased by 34.24% (1,066 vs. 1,431, P=0.000), significantly types included foreign bodies, falls, crush injuries, sharp injuries.During highest proportion whereas falls pandemic.During body toddler higher than (P=0.001),but preschooler (P<0.05). Conclusions:In circumstance COVID-19, significantly.It is necessary strengthen bodies toddler, preschooler.

Язык: Английский

Процитировано

4
Case report: unprecedented case of infantile cerebral infarction following COVID-19 and favorable outcome DOI Creative Commons

Shuhong Zheng,

Hairui Chen,

Weiwei Xu

и другие.

Frontiers in Immunology, Год журнала: 2024, Номер 15

Опубликована: Март 25, 2024

The 2019 novel coronavirus, SARS-CoV-2, was highly prevalent in China as of December 2022, causing a range symptoms, predominantly affecting the respiratory tract. While SARS-CoV-2 infection children is generally mild, severe cases, especially infants, are rare. We present case previously healthy 7-month-old infant who developed cerebral infarction and coagulation dysfunction three days after COVID-19 onset. Clinically, had weakness left limbs pinpoint bleeding spots. A cranial magnetic resonance imaging showed ischemic strokes right basal ganglia thalamus. Laboratory tests indicated thrombocytopenia dysfunction. Inflammatory cytokines like interleukin-10 were elevated, with increased CD3 + , CD4 CD8 T lymphocytes but decreased - CD16 CD56 natural killer cells. Treatment included mannitol, dexamethasone, oral aspirin, vitamins B1 B6 for reducing intracranial pressure, antiinflammation, anticoagulation, nerve support, respectively. During recovery phase, rehabilitation therapy focused on strength training, fine motor skills, massage therapy. gradually improved successfully recovered. rare, such cases can lead to complications. These combined efforts instrumental achieving significant functional patient, demonstrating that even instances pediatric due COVID-19, positive outcomes attainable early comprehensive medical response.

Язык: Английский

Процитировано

0