Abstract
Background
Quantitative
assessment
of
muscle
mass
is
a
critical
step
in
sarcopenia
disease
management.
Expanding
upon
the
use
ultrasound
foetal
growth
assessment,
we
established
and
validated
an
ultrasound-derived
system
for
older
adults
at
risk
sarcopenia.
Methods
A
total
669
were
recruited
three
cohorts
this
cross-sectional
study.
In
cohort
1(n
=
103),
most
valuable
sites
skeletal
index
(SMI)
estimation
located
among
11
scanning
sites.
An
SMI
estimating
algorithm
based
on
thickness
(MT)
was
obtained
modelling
group
composed
1
2
(n
309).
The
reliability
equation
validity
cut-off
values
verified
3
257),
which
selected
as
verification
group.
Results
group,
e-SMI
low
7.13
kg/m2
men
5.81
women.
intraclass
correlation
between
0.885.
sensitivity
detecting
93.6%
89.7%
women,
negative
predictive
value
94.9%
94.7%
Combined
with
handgrip
strength
gait
speed,
had
overall
diagnostic
92.7%
specificity
91.0%
Conclusion
can
be
promising
tool
potential
classification
tool.
PLoS ONE,
Год журнала:
2023,
Номер
18(1), С. e0281144 - e0281144
Опубликована: Янв. 30, 2023
This
study
aimed
to
examine
sarcopenia
prevalence
using
the
Asian
Working
Group
for
Sarcopenia
2019
(AWGS)
and
Foundation
National
Institutes
of
Health
(FNIH)
definitions,
their
associations
with
important
health
conditions
affecting
midlife
Singaporean
women.
Muscle
mass
function
were
objectively
assessed
in
1201
healthy
community-dwelling
subjects
aged
45–69
years
under
Integrated
Women’s
Program
(IWHP).
Dual-energy
X-ray
absorptiometry
(DXA),
handgrip
strength
Short
Physical
Performance
Battery
(SPPB)
measured,
relationship
between
hypertension,
type
2
diabetes
(T2DM),
osteoporosis,
depression/anxiety,
urinary
incontinence
examined
binary
logistic
regression
models.
was
18.0%
7.7%
by
AWGS
FNIH
criteria
respectively.
Osteoporosis
(aOR:
1.74,
95%
CI:
1.02,
2.94)
T2DM
1.98,
1.14,
3.42)
positively
associated
AWGS-
FNIH-defined
respectively,
while
hypertension
not,
after
adjustment
age,
ethnicity,
education
levels
menopausal
status.
A
negative
percent
agreement
95.6%
suggests
good
absence
sarcopenia.
Even
though
they
represent
a
single
concept,
either
criterion
differed
relationships
suggesting
need
further
rationalization
diagnostic
criteria.
Aging,
Год журнала:
2021,
Номер
13(6), С. 8599 - 8610
Опубликована: Март 10, 2021
In
this
study,
we
investigated
whether
nutrition
status
mediates
the
relationship
between
cognitive
decline
and
sarcopenia.
Sarcopenia
was
assessed
in
4023
community-dwelling
older
adults
from
West
China
using
AWGS
2014
diagnostic
criteria.
Cognitive
function
were
10-item
Short
Portable
Mental
Status
Questionnaire
(SPMSQ)
Mini
Nutrition
Assessment-Short
Form
(MNA-SF)
scale,
respectively.
Mediation
model
regression
analysis
demonstrated
that
negatively
associated
with
sarcopenia
(β
=
-0.521;
95%
CI:
-0.583
to
-0.459).
The
indirect
effects
of
on
significant
after
adjusting
for
age,
sex,
ethnicity
0.015;
0.012
0.017),
but
direct
not
statistically
adding
as
a
parameter
mediation
-0.001;
-0.008
0.005).
Structural
equation
(SEM)
framework
pathway
confirmed
association
status,
decline,
These
findings
demonstrate
negative
mediated
by
status.
We
therefore
postulate
maintaining
good
delays
adults.
Healthcare,
Год журнала:
2020,
Номер
8(4), С. 479 - 479
Опубликована: Ноя. 12, 2020
The
association
between
obesity
and
sarcopenia
remains
controversial.
present
study
was
conducted
to
explore
the
associations
among
body
mass
index
(BMI),
visceral
fat
area
(VFA),
in
older
people
analyze
their
potential
mechanisms.
This
cross-sectional
included
861
community-dwelling
Chinese
from
three
regions
of
China.
BMI,
VFA,
muscle
mass,
strength,
physical
performance,
composition,
metabolic
markers
were
measured.
Muscle
strength
positively
correlated
with
but
negatively
VFA.
Simple
overweight/obesity
associated
(OR
=
0.07,
95%
CI
0.03~0.18),
OR
value
lower
than
combined
0.16,
0.09~0.28).
Fat
free
total
protein
high
BMI
Furthermore,
VFA
adversely
some
risk
factors
sarcopenia.
Combination
increased
diagnostic
efficiency
low
In
conclusion,
sarcopenia,
while
attenuated
negative
opposite
may
partially
be
attributed
different
composition
Therefore,
bedsides
its
interaction
should
considered
prevention.
Abstract
Background
Quantitative
assessment
of
muscle
mass
is
a
critical
step
in
sarcopenia
disease
management.
Expanding
upon
the
use
ultrasound
foetal
growth
assessment,
we
established
and
validated
an
ultrasound-derived
system
for
older
adults
at
risk
sarcopenia.
Methods
A
total
669
were
recruited
three
cohorts
this
cross-sectional
study.
In
cohort
1(n
=
103),
most
valuable
sites
skeletal
index
(SMI)
estimation
located
among
11
scanning
sites.
An
SMI
estimating
algorithm
based
on
thickness
(MT)
was
obtained
modelling
group
composed
1
2
(n
309).
The
reliability
equation
validity
cut-off
values
verified
3
257),
which
selected
as
verification
group.
Results
group,
e-SMI
low
7.13
kg/m2
men
5.81
women.
intraclass
correlation
between
0.885.
sensitivity
detecting
93.6%
89.7%
women,
negative
predictive
value
94.9%
94.7%
Combined
with
handgrip
strength
gait
speed,
had
overall
diagnostic
92.7%
specificity
91.0%
Conclusion
can
be
promising
tool
potential
classification
tool.
