A comparative analysis of sarcopenia screening methods in Thai people with type 2 diabetes mellitus in an outpatient setting DOI Creative Commons

Ornpicha Laohajaroensombat,

Thanapat Limpaarayakul,

Nattapol Sathavarodom

и другие.

BMC Geriatrics, Год журнала: 2025, Номер 25(1)

Опубликована: Май 16, 2025

Type 2 Diabetes Mellitus (T2DM) is closely linked with sarcopenia. The lack of validated, easy, and effective sarcopenia screening tools for people T2DM may result in underdiagnosis, delayed interventions, worsening outcomes. This study evaluated compared the diagnostic accuracy various outpatients. A cross-sectional was conducted on 329 at Phramongkutklao Hospital, Thailand, between December 2023 November 2024. eight tools. Asian Working Group Sarcopenia 2019 (AWGS 2019) criteria served as reference standard. Sensitivity, Specificity, were using receiver operating characteristic (ROC) curve analysis. optimal cutoffs identified Youden index. prevalence 23.7%. Calf circumference showed highest standard cutoff (AUC: 0.892), optimised points < 37.0 cm males 36.0 females, achieved high sensitivity (90.1% males, 91.1% females) acceptable specificity (77.2% 67.8% females). Neck demonstrated utility 0.741) proposed thresholds 39.5 (males) 36.5 (females), yielding moderate (69.7% 82.2% (78.9% 62.6% Questionnaire-based limited SARC-CalF performing best 0.789, sensitivity: 48.7%, specificity: 93.2%). Among physical performance tests, handgrip strength most accurate 0.716), although these tests generally exhibited sensitivity, but lower specificity. tool T2DM. emerged a promising alternative values, offering simple, novel practice option. These findings support implementation anthropometric measures clinical settings, particularly outpatient care.

Язык: Английский

Exercise to Prevent and Manage Frailty and Fragility Fractures DOI Creative Commons
Elsa Dent, Robin M. Daly, Emiel O. Hoogendijk

и другие.

Current Osteoporosis Reports, Год журнала: 2023, Номер 21(2), С. 205 - 215

Опубликована: Март 28, 2023

This review identifies exercise-based recommendations to prevent and manage frailty fragility fractures from current clinical practice guidelines. We also critically assess recently published literature in relation exercise interventions mitigate fractures.

Язык: Английский

Процитировано

35

Are Dietary Patterns Relevant for Reducing the Risk of Fractures and Sarcopenia? DOI Creative Commons
Ailsa Welch, Jamie Scott, Donnie Cameron

и другие.

Current Osteoporosis Reports, Год журнала: 2025, Номер 23(1)

Опубликована: Янв. 23, 2025

Язык: Английский

Процитировано

1

Trajectories, Transitions, and Trends in Frailty among Older Adults: A Review DOI Creative Commons
Emiel O. Hoogendijk, Elsa Dent

Annals of Geriatric Medicine and Research, Год журнала: 2022, Номер 26(4), С. 289 - 295

Опубликована: Дек. 12, 2022

Frailty is an age-related clinical state associated with deterioration across multiple physiological systems and a leading cause of morbidity mortality later in life. To understand how frailty develops what causes its progression, longitudinal data repeated measurements are required. This review summarizes evidence from studies on trajectories, transitions, trends. We identified several consistent findings: increases aging dynamic condition, more recent generations older adults have higher levels. These findings both public health relevance, including the provision healthcare aged care services coming years. Further required, particularly those conducted low- middle-income countries investigating factors changes frailty. The latter may help develop better-targeted interventions to reverse or slow progression

Язык: Английский

Процитировано

31

Imaging modalities for measuring body composition in patients with cancer: opportunities and challenges DOI Open Access
Urvi A. Shah, Tarah J. Ballinger, Rusha Bhandari

и другие.

JNCI Monographs, Год журнала: 2023, Номер 2023(61), С. 56 - 67

Опубликована: Май 4, 2023

Abstract Body composition assessment (ie, the measurement of muscle and adiposity) impacts several cancer-related outcomes including treatment-related toxicities, treatment responses, complications, prognosis. Traditional modalities for body include mass index, circumference, skinfold thickness, bioelectrical impedance analysis; advanced imaging dual energy x-ray absorptiometry, computerized tomography, magnetic resonance imaging, positron emission tomography. Each modality has its advantages disadvantages, thus requiring an individualized approach in identifying most appropriate measure specific clinical or research situations. Advancements approaches have led to abundance available data, however, lack standardized thresholds classification abnormal adiposity been a barrier adopting these measurements widely care. In this review, we discuss different detail provide guidance on their unique opportunities challenges.

Язык: Английский

Процитировано

19

A Critical Review of Current Worldwide Definitions of Sarcopenia DOI
Haya F. Alhmly, Roger A. Fielding

Calcified Tissue International, Год журнала: 2023, Номер 114(1), С. 74 - 81

Опубликована: Дек. 3, 2023

Язык: Английский

Процитировано

15

Individualized Hospital to Home, Exercise-Nutrition Self-Managed Intervention for Pre-Frail and Frail Hospitalized Older Adults: The INDEPENDENCE Randomized Controlled Pilot Trial DOI Creative Commons
Chad Yixian Han, Yogesh Sharma, Alison Yaxley

и другие.

Clinical Interventions in Aging, Год журнала: 2023, Номер Volume 18, С. 809 - 825

Опубликована: Май 1, 2023

Purpose: Pre-frailty and frailty in older adults are associated with poor health outcomes increase health-care costs, further worsening during hospitalization. This study aimed to examine the effect of an individualized hospital home, exercise-nutrition self-managed intervention for pre-frail frail hospitalized adults. Patients Methods: Older admitted acute medical unit a tertiary South Australia who were or recruited from September 2020 June 2021, randomized either control group followed up at 3 6 months. The outcome variables program adherence, status by Edmonton Frail Scale (EFS) score, lower extremity physical function, handgrip strength, nutritional status, cognition, mood, health-related quality life, risk functional decline, unplanned readmissions. Results: Participants 79.2 ± 6.6 years old, 63% female, mostly (67%), EFS 8.6± 1.9. Adherence inpatient home visits/telehealth high (91± 13% 92± 21%, respectively). Intention-to-treat analysis using linear regression models showed that participants had significantly greater reduction (− 3.0; 95% CI: − 4.8 3.0) months 2.5; 3.8 1.0, P < 0.001 both) compared group; particularly performance component. There also improvements overall Short Physical Performance Battery score (4.0; 1.3 6.6) (3.9; 1.0 6.9, 0.05 both), mini-mental state examination (2.6; 0.3– 4.8, =0.029) strength (3.7; 0.2– 7.1, =0.039) Geriatric Depression Scale, 2.2; 4.1 0.30, =0.026) as control. Conclusion: provided evidence acceptability patient may benefit alleviate pre-frailty hospitalised Keywords: frailty, self-management, exercise, nutrition therapy

Язык: Английский

Процитировано

13

The rising tsunami of poor muscle health and sarcopenia in Asia-Pacific: Time for focused attention and targeted interventions DOI
Samuel Teong Huang Chew, Nguyễn Thị Thu Hoài, Shashank Joshi

и другие.

Archives of Gerontology and Geriatrics, Год журнала: 2023, Номер 117, С. 105275 - 105275

Опубликована: Ноя. 12, 2023

Язык: Английский

Процитировано

13

High Sarcopenia Awareness Contrasts a Lack of Clinical Implementation Among Geriatric Rehabilitation Health Care Professionals in the Netherlands: EMPOWER-GR DOI Creative Commons
Laure M. G. Verstraeten, Janneke P. van Wijngaarden, Carel G. M. Meskers

и другие.

Journal of Geriatric Physical Therapy, Год журнала: 2023, Номер 47(2), С. 67 - 76

Опубликована: Фев. 24, 2023

Background and Purpose: Despite being associated with serious adverse outcomes, such as mortality, sarcopenia remains largely undiagnosed in older individuals. This study aimed to assess the awareness, practices, barriers enablers clinical implementation of diagnosis treatment among geriatric rehabilitation health care professionals Netherlands. Methods: As part EMPOWER-GR, a cross-sectional survey working Netherlands was undertaken between September 23, 2020, January 28, 2021. Professionals were recruited via provider, professional associations, networks research team, social media. Descriptive statistics used outcomes. Results Discussion: Of 501 professionals, 12.2% physicians, 23.0% physical therapist/occupational therapists, 30.3% dietitians, 19.6% nurses, 11.0% assistants. The concept known by 83.8% participants, 92.5% correctly identified low muscle mass strength (and performance), 73.8% very important management adults admitted for rehabilitation. Although 26.2% 18.9% participants reported screening diagnosing sarcopenia, respectively, their current practice, only 3.0% adequately (revised) definition European Working Group on Sarcopenia Older People. When has been diagnosed, 65.0% initiating consisting resistance exercise training (78.7%), food fortification/high-energy or protein diet (85.4%), oral nutritional supplements (70.4%). Most lack knowledge, access tools, equipment time, while protocol implementation, training, clear responsibilities. Conclusions: awareness is high Netherlands, but adequate almost nonexistent which hampers interventions. Better responsibilities, tools protocols, well prioritization, are needed be diagnosed treated

Язык: Английский

Процитировано

11

Omega-3 polyunsatured fatty acids and physical performance across the lifespan: a narrative review DOI Creative Commons
Domenico Azzolino,

Camilla Bertoni,

Valentina De Cosmi

и другие.

Frontiers in Nutrition, Год журнала: 2024, Номер 11

Опубликована: Июнь 20, 2024

Background and Aims Physical performance is a major contributor of mobility independence during older life. Despite progressive decline in musculoskeletal function starts from middle age, several factors acting the life-course can negatively influence functional capacities. Lifestyle interventions incorporating nutrition physical exercise help maximizing muscle capacities early life as well preserving them later Among various dietary compounds, omega-3 polyunsaturated fatty acids (PUFAs) are gaining growing attention for their potential effects on membrane composition function. Indeed, pathways enhanced, such an attenuation pro-inflammatory oxidative stress, mitochondrial function, activation mammalian target rapamycin (mTOR) signaling reduction insulin resistance. Methods We performed narrative review to explore existing literature relationship between PUFAs across life-course. Results Growing evidence randomized controlled trials (RCTs) suggests beneficial including parameters mid On other hand, despite direct association not available literature, some mechanisms by which may contribute improved adult could be hypothesized. Conclusion Omega-3 positive effect parameters. The integration measures future studies would great interest whether starting extending throughout lifespan. However, larger high-quality RCTs needed fully elucidate supplementation mass

Язык: Английский

Процитировано

4

Association of Bioelectrical Impedance Phase Angle with Physical Performance and Nutrient Intake of Older Adults DOI Open Access
Sandra Unterberger, Rudolf Aschauer, Patrick A. Zöhrer

и другие.

Nutrients, Год журнала: 2023, Номер 15(6), С. 1458 - 1458

Опубликована: Март 17, 2023

In recent years, the phase angle (PhA) as a raw bioelectrical impedance analysis variable has gained attention to assess cell integrity and its association physical performance in either sports-related or clinical settings. However, data on healthy older adults are scarce. Therefore, body composition, macronutrient intake from (n = 326, 59.2% women, 75.2 ± 7.2 years) were retrospectively analyzed. Physical was evaluated by Senior Fitness Test battery, gait speed, timed up go handgrip strength. Body composition determined BIA dual-energy X-ray absorptiometry (from subgroup of n 51). The PhA negatively associated with test age (r −0.312 −0.537, p < 0.001), positively 6 min walk test, 30 s chair stand, strength, speed score 0.170–0.554, 0.05), but not protein 0.050, 0.386). Hierarchical multiple regression showed that especially age, sex, BMI, also predicted outcomes. conclusion, seems be an interesting contributor performance, sex- age-specific norm values still need determined.

Язык: Английский

Процитировано

9