Type
2
Diabetes
Mellitus
(T2DM)
is
closely
linked
with
sarcopenia.
The
lack
of
validated,
easy,
and
effective
sarcopenia
screening
tools
for
people
T2DM
may
result
in
underdiagnosis,
delayed
interventions,
worsening
outcomes.
This
study
evaluated
compared
the
diagnostic
accuracy
various
outpatients.
A
cross-sectional
was
conducted
on
329
at
Phramongkutklao
Hospital,
Thailand,
between
December
2023
November
2024.
eight
tools.
Asian
Working
Group
Sarcopenia
2019
(AWGS
2019)
criteria
served
as
reference
standard.
Sensitivity,
Specificity,
were
using
receiver
operating
characteristic
(ROC)
curve
analysis.
optimal
cutoffs
identified
Youden
index.
prevalence
23.7%.
Calf
circumference
showed
highest
standard
cutoff
(AUC:
0.892),
optimised
points
<
37.0
cm
males
36.0
females,
achieved
high
sensitivity
(90.1%
males,
91.1%
females)
acceptable
specificity
(77.2%
67.8%
females).
Neck
demonstrated
utility
0.741)
proposed
thresholds
39.5
(males)
36.5
(females),
yielding
moderate
(69.7%
82.2%
(78.9%
62.6%
Questionnaire-based
limited
SARC-CalF
performing
best
0.789,
sensitivity:
48.7%,
specificity:
93.2%).
Among
physical
performance
tests,
handgrip
strength
most
accurate
0.716),
although
these
tests
generally
exhibited
sensitivity,
but
lower
specificity.
tool
T2DM.
emerged
a
promising
alternative
values,
offering
simple,
novel
practice
option.
These
findings
support
implementation
anthropometric
measures
clinical
settings,
particularly
outpatient
care.
Current Osteoporosis Reports,
Год журнала:
2023,
Номер
21(2), С. 205 - 215
Опубликована: Март 28, 2023
This
review
identifies
exercise-based
recommendations
to
prevent
and
manage
frailty
fragility
fractures
from
current
clinical
practice
guidelines.
We
also
critically
assess
recently
published
literature
in
relation
exercise
interventions
mitigate
fractures.
Annals of Geriatric Medicine and Research,
Год журнала:
2022,
Номер
26(4), С. 289 - 295
Опубликована: Дек. 12, 2022
Frailty
is
an
age-related
clinical
state
associated
with
deterioration
across
multiple
physiological
systems
and
a
leading
cause
of
morbidity
mortality
later
in
life.
To
understand
how
frailty
develops
what
causes
its
progression,
longitudinal
data
repeated
measurements
are
required.
This
review
summarizes
evidence
from
studies
on
trajectories,
transitions,
trends.
We
identified
several
consistent
findings:
increases
aging
dynamic
condition,
more
recent
generations
older
adults
have
higher
levels.
These
findings
both
public
health
relevance,
including
the
provision
healthcare
aged
care
services
coming
years.
Further
required,
particularly
those
conducted
low-
middle-income
countries
investigating
factors
changes
frailty.
The
latter
may
help
develop
better-targeted
interventions
to
reverse
or
slow
progression
JNCI Monographs,
Год журнала:
2023,
Номер
2023(61), С. 56 - 67
Опубликована: Май 4, 2023
Abstract
Body
composition
assessment
(ie,
the
measurement
of
muscle
and
adiposity)
impacts
several
cancer-related
outcomes
including
treatment-related
toxicities,
treatment
responses,
complications,
prognosis.
Traditional
modalities
for
body
include
mass
index,
circumference,
skinfold
thickness,
bioelectrical
impedance
analysis;
advanced
imaging
dual
energy
x-ray
absorptiometry,
computerized
tomography,
magnetic
resonance
imaging,
positron
emission
tomography.
Each
modality
has
its
advantages
disadvantages,
thus
requiring
an
individualized
approach
in
identifying
most
appropriate
measure
specific
clinical
or
research
situations.
Advancements
approaches
have
led
to
abundance
available
data,
however,
lack
standardized
thresholds
classification
abnormal
adiposity
been
a
barrier
adopting
these
measurements
widely
care.
In
this
review,
we
discuss
different
detail
provide
guidance
on
their
unique
opportunities
challenges.
Clinical Interventions in Aging,
Год журнала:
2023,
Номер
Volume 18, С. 809 - 825
Опубликована: Май 1, 2023
Purpose:
Pre-frailty
and
frailty
in
older
adults
are
associated
with
poor
health
outcomes
increase
health-care
costs,
further
worsening
during
hospitalization.
This
study
aimed
to
examine
the
effect
of
an
individualized
hospital
home,
exercise-nutrition
self-managed
intervention
for
pre-frail
frail
hospitalized
adults.
Patients
Methods:
Older
admitted
acute
medical
unit
a
tertiary
South
Australia
who
were
or
recruited
from
September
2020
June
2021,
randomized
either
control
group
followed
up
at
3
6
months.
The
outcome
variables
program
adherence,
status
by
Edmonton
Frail
Scale
(EFS)
score,
lower
extremity
physical
function,
handgrip
strength,
nutritional
status,
cognition,
mood,
health-related
quality
life,
risk
functional
decline,
unplanned
readmissions.
Results:
Participants
79.2
±
6.6
years
old,
63%
female,
mostly
(67%),
EFS
8.6±
1.9.
Adherence
inpatient
home
visits/telehealth
high
(91±
13%
92±
21%,
respectively).
Intention-to-treat
analysis
using
linear
regression
models
showed
that
participants
had
significantly
greater
reduction
(−
3.0;
95%
CI:
−
4.8
3.0)
months
2.5;
3.8
1.0,
P
<
0.001
both)
compared
group;
particularly
performance
component.
There
also
improvements
overall
Short
Physical
Performance
Battery
score
(4.0;
1.3
6.6)
(3.9;
1.0
6.9,
0.05
both),
mini-mental
state
examination
(2.6;
0.3–
4.8,
=0.029)
strength
(3.7;
0.2–
7.1,
=0.039)
Geriatric
Depression
Scale,
2.2;
4.1
0.30,
=0.026)
as
control.
Conclusion:
provided
evidence
acceptability
patient
may
benefit
alleviate
pre-frailty
hospitalised
Keywords:
frailty,
self-management,
exercise,
nutrition
therapy
Journal of Geriatric Physical Therapy,
Год журнала:
2023,
Номер
47(2), С. 67 - 76
Опубликована: Фев. 24, 2023
Background
and
Purpose:
Despite
being
associated
with
serious
adverse
outcomes,
such
as
mortality,
sarcopenia
remains
largely
undiagnosed
in
older
individuals.
This
study
aimed
to
assess
the
awareness,
practices,
barriers
enablers
clinical
implementation
of
diagnosis
treatment
among
geriatric
rehabilitation
health
care
professionals
Netherlands.
Methods:
As
part
EMPOWER-GR,
a
cross-sectional
survey
working
Netherlands
was
undertaken
between
September
23,
2020,
January
28,
2021.
Professionals
were
recruited
via
provider,
professional
associations,
networks
research
team,
social
media.
Descriptive
statistics
used
outcomes.
Results
Discussion:
Of
501
professionals,
12.2%
physicians,
23.0%
physical
therapist/occupational
therapists,
30.3%
dietitians,
19.6%
nurses,
11.0%
assistants.
The
concept
known
by
83.8%
participants,
92.5%
correctly
identified
low
muscle
mass
strength
(and
performance),
73.8%
very
important
management
adults
admitted
for
rehabilitation.
Although
26.2%
18.9%
participants
reported
screening
diagnosing
sarcopenia,
respectively,
their
current
practice,
only
3.0%
adequately
(revised)
definition
European
Working
Group
on
Sarcopenia
Older
People.
When
has
been
diagnosed,
65.0%
initiating
consisting
resistance
exercise
training
(78.7%),
food
fortification/high-energy
or
protein
diet
(85.4%),
oral
nutritional
supplements
(70.4%).
Most
lack
knowledge,
access
tools,
equipment
time,
while
protocol
implementation,
training,
clear
responsibilities.
Conclusions:
awareness
is
high
Netherlands,
but
adequate
almost
nonexistent
which
hampers
interventions.
Better
responsibilities,
tools
protocols,
well
prioritization,
are
needed
be
diagnosed
treated
Frontiers in Nutrition,
Год журнала:
2024,
Номер
11
Опубликована: Июнь 20, 2024
Background
and
Aims
Physical
performance
is
a
major
contributor
of
mobility
independence
during
older
life.
Despite
progressive
decline
in
musculoskeletal
function
starts
from
middle
age,
several
factors
acting
the
life-course
can
negatively
influence
functional
capacities.
Lifestyle
interventions
incorporating
nutrition
physical
exercise
help
maximizing
muscle
capacities
early
life
as
well
preserving
them
later
Among
various
dietary
compounds,
omega-3
polyunsaturated
fatty
acids
(PUFAs)
are
gaining
growing
attention
for
their
potential
effects
on
membrane
composition
function.
Indeed,
pathways
enhanced,
such
an
attenuation
pro-inflammatory
oxidative
stress,
mitochondrial
function,
activation
mammalian
target
rapamycin
(mTOR)
signaling
reduction
insulin
resistance.
Methods
We
performed
narrative
review
to
explore
existing
literature
relationship
between
PUFAs
across
life-course.
Results
Growing
evidence
randomized
controlled
trials
(RCTs)
suggests
beneficial
including
parameters
mid
On
other
hand,
despite
direct
association
not
available
literature,
some
mechanisms
by
which
may
contribute
improved
adult
could
be
hypothesized.
Conclusion
Omega-3
positive
effect
parameters.
The
integration
measures
future
studies
would
great
interest
whether
starting
extending
throughout
lifespan.
However,
larger
high-quality
RCTs
needed
fully
elucidate
supplementation
mass
Nutrients,
Год журнала:
2023,
Номер
15(6), С. 1458 - 1458
Опубликована: Март 17, 2023
In
recent
years,
the
phase
angle
(PhA)
as
a
raw
bioelectrical
impedance
analysis
variable
has
gained
attention
to
assess
cell
integrity
and
its
association
physical
performance
in
either
sports-related
or
clinical
settings.
However,
data
on
healthy
older
adults
are
scarce.
Therefore,
body
composition,
macronutrient
intake
from
(n
=
326,
59.2%
women,
75.2
±
7.2
years)
were
retrospectively
analyzed.
Physical
was
evaluated
by
Senior
Fitness
Test
battery,
gait
speed,
timed
up
go
handgrip
strength.
Body
composition
determined
BIA
dual-energy
X-ray
absorptiometry
(from
subgroup
of
n
51).
The
PhA
negatively
associated
with
test
age
(r
−0.312
−0.537,
p
<
0.001),
positively
6
min
walk
test,
30
s
chair
stand,
strength,
speed
score
0.170–0.554,
0.05),
but
not
protein
0.050,
0.386).
Hierarchical
multiple
regression
showed
that
especially
age,
sex,
BMI,
also
predicted
outcomes.
conclusion,
seems
be
an
interesting
contributor
performance,
sex-
age-specific
norm
values
still
need
determined.