Anticancer and Acute Toxicity Studies of Cellulose-Coated Vanadium Oxide Nanomaterials DOI

Zartasha Sarwar,

Muhammad Khawar Abbas,

Naveed Akhtar Shad

и другие.

Journal of Molecular Structure, Год журнала: 2024, Номер 1322, С. 140633 - 140633

Опубликована: Ноя. 6, 2024

Язык: Английский

Advances in pyrazolo[1,5-a]pyrimidines: synthesis and their role as protein kinase inhibitors in cancer treatment DOI Creative Commons

Terungwa H. Iorkula,

Osasere Jude-Kelly Osayawe,

Daniel A. Odogwu

и другие.

RSC Advances, Год журнала: 2025, Номер 15(5), С. 3756 - 3828

Опубликована: Янв. 1, 2025

Pyrazolo[1,5- a ]pyrimidines are notable class of heterocyclic compounds with potent protein kinase inhibitor (PKI) activity, playing critical role in targeted cancer therapy.

Язык: Английский

Процитировано

3
Dual Functionality of Cobalt Oxide Nanoparticles: Exploring Their Potential as Antimicrobial and Anticancer Agents DOI
Ikhazuagbe H. Ifijen,

Emmanuel Faderin,

C. O. OKAFOR

и другие.

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Янв. 29, 2025

Язык: Английский

Процитировано

1
Lactoferrin Nanoparticle-Vanadium Complex: A Promising High-Efficiency Agent against Glioblastoma by Triggering Autophagy and Ferroptosis DOI

Shuangshuang Gai,

Qiwei Yan,

Shan Li

и другие.

Journal of Medicinal Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Фев. 13, 2025

Glioblastoma represents the most aggressive type of brain cancer with minimal clinical advancements in recent decades attributed to absence efficient drug delivery strategies. In this study, we synthesized a series vanadium complexes (V1-V4) and then constructed lactoferrin (LF)-V4 nanoparticle (NP) system. The nanoplatform crossed blood-brain barrier by binding low-density lipoprotein receptor-associated protein-1 selectively targeted glioblastoma, ultimately inhibiting growth situ glioblastoma tumors. LF-V4 NPs induced autophagic cell death U87-MG cells generating reactive oxygen species (ROS) that damaged mitochondria. Further studies revealed triggered lipid peroxidation through accumulation ROS, depletion GSH, downregulation GPX4 SLC7A11, leading ferroptosis cells.

Язык: Английский

Процитировано

1
Novel MOF-based vanadium and 2,2 -bipyridine-4,4 -dicarboxylic acid as phenomenal dye adsorbent and antimicrobial agent DOI Creative Commons

Baraa Mohammed Yaseen,

Farag M. A. Altalbawy, Rafid Jihad Albadr

и другие.

Frontiers in Chemistry, Год журнала: 2025, Номер 13

Опубликована: Янв. 30, 2025

In this study, a new MOF (metal-organic framework) based on vanadium and 2,2-bipyridine-4,4-dicarboxylic acid (V/BP-MOF) was synthesized. Synthesized V/BP-MOF introduced as strong adsorbent of Congo Red (CR) an effective agent in eliminating microbial species. the investigation CR absorption activity, several factors such concentration V/BP-MOF, pH, time, temperature were investigated. Antimicrobial evaluations carried out Common bacterial strains wastewater values MIC (minimum inhibitory concentration) MBC (Minimum Bactericidal Concentration) reported. The confirmed characterized by EA, EDS, EDS mapping, FT-IR, XRD, TGA, BET, SEM, TEM. checking characteristics size, specific surface area, thermal stability obtained, respectively, 68 nm, 325 m 2 /g, 320°C. highest adsorption CR, at 94%, obtained natural ambient temperature, after 150 min. kinetic studies, correlation coefficient 0.99 observed with pseudo-second-order model, while isotherm 0.97 Freundlich model. biological evaluations, best inhibition against Escherichia coli , 4 μg/mL μg/mL, respectively. As general result, can be potent absorbent dye antimicrobial properties. Therefore, compound synthesized study suitable option for treatment industry, multiple capabilities including removal chemical pollutants pathogenic agents.

Язык: Английский

Процитировано

0
Green synthesis of Ag/V2O5 and Ag/V2O5-curdlan nanocomposites from Sargassum latifolium extract for enhanced antimicrobial and antioxidant activities DOI
Yasser A. Shaban,

Mohamed I. Orif,

Mohamed A. Ghandourah

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 301, С. 140472 - 140472

Опубликована: Янв. 30, 2025

Язык: Английский

Процитировано

0
Multifunctional Iron–Silver (Fe–Ag) Nanocomposites for Combined Anticancer Therapies: A Pathway to Enhanced Treatment Outcomes DOI

Emmanuel Faderin,

Terungwa H. Iorkula,

Kolawole E. Adesina

и другие.

˜The œminerals, metals & materials series, Год журнала: 2025, Номер unknown, С. 25 - 39

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Fabrication of Membranes Using Graphene Oxide Nanosheets: Advances, Challenges, and Future Directions DOI

Ogunnaike Korede Lekan,

Janefrances U. Chukwu,

Stella Eberechi Obuba

и другие.

˜The œminerals, metals & materials series, Год журнала: 2025, Номер unknown, С. 21 - 35

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
The Role of Calcium Phosphate Nanoparticles in Dental Materials: Properties, Applications, and Future Prospects DOI
Omowunmi Rebecca Aworinde,

Chimezie O. Onukwuli,

Kolawole E. Adesina

и другие.

˜The œminerals, metals & materials series, Год журнала: 2025, Номер unknown, С. 693 - 710

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
The Utilization of Cellulose Nanocrystals-Infused Hydrogels for Enhanced Efficacy in Cancer Chemotherapy DOI

Terungwa H. Iorkula,

Emmanuel Faderin,

Rofiat Odunayo Kajola

и другие.

˜The œminerals, metals & materials series, Год журнала: 2025, Номер unknown, С. 1021 - 1036

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0
Lanthanum-based nanoparticles: A promising frontier in antimicrobial applications DOI
Ikhazuagbe H. Ifijen,

Peter Agyemang,

Emmanuel Faderin

и другие.

Next Materials, Год журнала: 2025, Номер 8, С. 100719 - 100719

Опубликована: Май 23, 2025

Язык: Английский

Процитировано

0