Biomolecules, Год журнала: 2025, Номер 15(6), С. 781 - 781

Опубликована: Май 28, 2025

Cancer remains a prevalent global health concern, with key factors such as diet, environment, and genetics playing significant roles in its progression. Matrix metalloproteinases (MMPs), particularly MMP-2 MMP-9, play critical role cancer progression by degrading the extracellular matrix, thereby facilitating tumor growth metastasis. Wine contains various bioactive compounds, including caffeic acid, gallic kaempferol, naringenin, quercetin, myricetin, resveratrol, epigallocatechin gallate, riboflavin, folic which have shown promise inhibiting cell proliferation These compounds been reported to downregulate activity and/or expression of thus potentially suppressing However, excessive alcohol consumption can lead addiction elevate risk complications, fatty liver disease, cardiovascular damage, stroke, kidney failure. Despite these concerns, moderate wine has associated potential anticancer properties restricting In this review, we summarize discuss how molecules regulate MMP-9 through derived from explore their implications for treatment.

Язык: Английский