Elevated risk of perioperative ischemic stroke in noncardiac surgery patients with atrial fibrillation: a retrospective cohort study

BMC Anesthesiology, Год журнала: 2025, Номер 25(1)

Опубликована: Апрель 2, 2025

Stroke is still a significant and growing challenge of global health, however, the impact Atrial Fibrillation (AF) on risk perioperative stroke remains unclear. This study aims to evaluate clinical prognostic value AF in patients undergoing noncardiac surgery, with ischemic as primary indicator. A retrospective cohort was conducted who underwent surgery between January 2008 August 2019 at The First Medical Center Chinese People's Liberation Army (PLA) General Hospital. included procedure duration exceeding one hour. Participants were categorized into two groups: an group non-AF group, based presence or absence AF. outcome occurrence stroke. To determine whether independent indicator, subgroup analyses performed. Logistic regression models used identify factors. Besides, sensitivity analysis, propensity score matching (PSM) analysis applied mitigate potential residual confounding effects assess robustness findings. demonstrated that had significantly higher (OR: 6.843; 95% CI: 3.73-11.413; P < 0.001). Further modeling confirmed correlation across various models: model 2 1.789; 0.958-3.053; 0.05), 3 5.121; 2.749-8.716; 0.001), 4 2.122; 1.123-3.677; 0.05). Sensitivity excluding neurosurgeries conducted. adjusted OR neurosurgery 1.623(95% 0.359-5.165; = 0.463). While, association remained stable those non-neurosurgical 2.154;95% 1.044-3.964; 0.023). After PSM adjustments, 2.106; 1.003-4.159; Subgroup revealed increased stroke, particularly males, aged ≥ 60.5 years, ASA 3, hypertension, not antiplatelet medication. fibrillation factor for especially pronounced specific subgroups, including elderly patients, high scores, receiving therapy. These findings emphasize need heightened awareness prompt intervention these high-risk patients.

Язык: Английский

Stroke after heart valve surgery: a single center institution report

Journal of Cardiothoracic Surgery, Год журнала: 2024, Номер 19(1)

Опубликована: Сен. 9, 2024

Язык: Английский