Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors DOI Creative Commons
Jie Huang, Xiaowei Zhang,

Luyao Ding

и другие.

Frontiers in Aging Neuroscience, Год журнала: 2025, Номер 17

Опубликована: Май 30, 2025

Background The neutrophil-percentage-to-albumin ratio (NPAR) functions as an integrative marker representing inflammatory response and nutritional health. However, its association with mortality in elderly stroke survivors has not been explored. Methods This cohort study analyzed data from 1,026 the National Health Nutrition Examination Survey (NHANES, 1999-2018). of NPAR was using Cox proportional hazards regression, restricted cubic splines (RCS), Kaplan-Meier survival analysis, time-dependent receiver operating characteristic (ROC) curves. Subgroup analyses interaction tests were also performed. Results During 6.65-year median follow-up, elevated showed independent associations increased all-cause cardiovascular mortality. Quartile-based analysis revealed 69 87% greater for highest versus lowest groups, respectively. RCS a non-linear threshold effect at = 14.5, beyond which risk sharply. demonstrated stable predictive accuracy, AUC ranging 0.664 to 0.607 0.652-0.609 over 3-10 years. confirmed consistency across different sex, BMI, lifestyle habits, comorbidity categories. Conclusion underscores strong positive correlation between prognosis older adult United States, indicating potential novel biomarker prognostic assessment.

Язык: Английский

Neutrophil infiltration and microglial shifts in sepsis induced preterm brain injury: pathological insights DOI Creative Commons

Jinjin Zhu,

He Tiantian,

Ziwei Huang

и другие.

Acta Neuropathologica Communications, Год журнала: 2025, Номер 13(1)

Опубликована: Апрель 21, 2025

Язык: Английский

Процитировано

0
ATF3 Restoration as a Potential Strategy in Managing Ulcerative Colitis: Implications from Sishen Pill Research DOI
Yutong Jin,

Xuetao Dong,

Weilong Zhong

и другие.

Phytomedicine, Год журнала: 2025, Номер 142, С. 156814 - 156814

Опубликована: Апрель 27, 2025

Язык: Английский

Процитировано

0
Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors DOI Creative Commons
Jie Huang, Xiaowei Zhang,

Luyao Ding

и другие.

Frontiers in Aging Neuroscience, Год журнала: 2025, Номер 17

Опубликована: Май 30, 2025

Background The neutrophil-percentage-to-albumin ratio (NPAR) functions as an integrative marker representing inflammatory response and nutritional health. However, its association with mortality in elderly stroke survivors has not been explored. Methods This cohort study analyzed data from 1,026 the National Health Nutrition Examination Survey (NHANES, 1999-2018). of NPAR was using Cox proportional hazards regression, restricted cubic splines (RCS), Kaplan-Meier survival analysis, time-dependent receiver operating characteristic (ROC) curves. Subgroup analyses interaction tests were also performed. Results During 6.65-year median follow-up, elevated showed independent associations increased all-cause cardiovascular mortality. Quartile-based analysis revealed 69 87% greater for highest versus lowest groups, respectively. RCS a non-linear threshold effect at = 14.5, beyond which risk sharply. demonstrated stable predictive accuracy, AUC ranging 0.664 to 0.607 0.652-0.609 over 3-10 years. confirmed consistency across different sex, BMI, lifestyle habits, comorbidity categories. Conclusion underscores strong positive correlation between prognosis older adult United States, indicating potential novel biomarker prognostic assessment.

Язык: Английский

Процитировано

0