Dysmetabolic comorbidities and non-alcoholic fatty liver disease: a stairway to metabolic dysfunction-associated steatotic liver disease
Hepatoma Research,
Год журнала:
2024,
Номер
10, С. 16 - 16
Опубликована: Янв. 1, 2024
Non-alcoholic
fatty
liver
disease
(NAFLD)
is
the
most
common
cause
of
chronic
disease.
This
term
does
not
describe
pathogenetic
mechanisms
and
complications
associated
with
NAFLD.
The
new
definition,
Metabolic
Dysfunction-associated
Steatotic
Liver
(MASLD),
emphasizes
relationship
between
NAFLD
cardiometabolic
comorbidities.
Cardiovascular
features,
such
as
arterial
hypertension
atherosclerosis,
are
frequently
patients
MASLD.
Furthermore,
these
have
a
high
risk
developing
neoplastic
diseases,
primarily
hepatocellular
carcinoma,
but
also
extrahepatic
tumors,
esophageal,
gastric,
pancreatic
cancers.
Moreover,
several
studies
showed
correlation
MASLD
endocrine
imbalance
gut
microbiota,
systemic
inflammation,
obesity,
insulin
resistance
play
key
role
in
development
complications.
narrative
review
aims
to
clarify
evolution
from
nomenclature
evaluate
its
Язык: Английский
Evolving liver disease insights from NAFLD to MASLD
Trends in Endocrinology and Metabolism,
Год журнала:
2024,
Номер
35(8), С. 683 - 686
Опубликована: Фев. 29, 2024
Язык: Английский
Valorizing Agro‐Food Waste for Nutraceutical Development: Sustainable Approaches for Managing Metabolic Dysfunction‐Associated Steatotic Liver Disease and Related Co‐Morbidities
Food Frontiers,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 25, 2024
ABSTRACT
This
comprehensive
investigation
delves
into
the
interconnectedness
of
different
features
cardiometabolic
syndrome,
such
as
metabolic
dysfunction‐associated
steatotic
liver
disease
(MASLD),
atherosclerotic
cardiovascular
(ASCVD),
and
gut
dysbiosis,
highlighting
crucial
role
nutraceuticals
in
their
management
prevention.
Given
significant
overlap
pathophysiology
these
conditions,
treatment
with
nutraceuticals,
especially
those
derived
from
agro‐food
waste,
offers
a
promising,
sustainable,
innovative
approach
to
healthcare.
The
2030
Agenda
for
Sustainable
Development
One
Health
concept
are
key
frameworks
selecting
most
interesting
supply
chain
production
ensuring
environmental
sustainability,
agricultural
practices.
In
this
review,
therapeutic
potential
kiwifruit
apples
has
been
explored,
detailing
how
bioactive
compounds,
like
polyphenols,
fiber,
pectin,
kaempferol,
phloretin,
phlorizin,
may
contribute
MASLD,
ASCVD,
dysbiosis.
Various
extraction
methods
active
ingredients,
including
chemical,
water,
enzyme
extractions,
analyzed
respective
benefits
drawbacks.
By
integrating
scientific
research,
sustainable
practices,
methods,
we
can
develop
effective
strategies
combat
pervasive
health
issues.
holistic
not
only
enhances
individual
outcomes
but
also
supports
broader
societal
goals,
promoting
healthier
future
all.
Язык: Английский