Опубликована: Янв. 1, 2024
Язык: Английский
Опубликована: Янв. 1, 2024
Язык: Английский
The Nucleus, Год журнала: 2024, Номер 67(1), С. 1 - 4
Опубликована: Апрель 1, 2024
A new era of genetics dawned in the 2010s with discovery revolutionary CRISPR/Cas technology, which enables targeting and editing specific genes or genomic loci high precision [4].Since then, CRISPR-Cas has become a household name, as it quite literally democratized genome across globe due to its versatility, flexibility, efficiency, relative ease adoption diverse biological systems.Conventional CRISPR-Cas9 advanced tools like base editors prime have principal for disrupting gene functions, replacing alleles, creating precise insertions deletions, conducting large-scale chromosome engineering [11].However, there are numerous challenges that must be addressed fully realize potential this technology.Base Editing (BE), Prime (PE) Homology-Directed Repair (HDR) offer capability allele swapping.However, efficiency PE HDR higher eukaryotes, particularly plants, is currently low requires further enhancement enable routine application crop improvement [17].The delivery CRISPR reagents cell types their encapsulation within cargo vehicles pose significant challenges.Furthermore, regeneration edited plants remains problematic many recalcitrant crops.Addressing polyploid crops necessitates dedicated attention.
Язык: Английский
Процитировано
3Journal of Fungi, Год журнала: 2025, Номер 11(3), С. 207 - 207
Опубликована: Март 6, 2025
Sorghum (Sorghum bicolor L.) is a globally important energy and food crop that becoming increasingly integral to security the environment. However, its production significantly hampered by various fungal phytopathogens affect yield quality. This review aimed provide comprehensive overview of major affecting sorghum, their impact, current management strategies, potential future directions. The diseases covered include anthracnose, grain mold complex, charcoal rot, downy mildew, rust, with an emphasis on pathogenesis, symptomatology, overall economic, social, environmental impacts. From initial use fungicides shift biocontrol, rotation, intercropping, modern tactics breeding resistant cultivars against mentioned are discussed. In addition, this explores disease management, particular focus role technology, including digital agriculture, predictive modeling, remote sensing, IoT devices, in early warning, detection, management. It also key policy recommendations support farmers advance research thus emphasizing need for increased investment research, strengthening extension services, facilitating access necessary inputs, implementing effective regulatory policies. concluded although pose significant challenges, combined effort innovative policies can mitigate these issues, enhance resilience sorghum facilitate global issues.
Язык: Английский
Процитировано
0Опубликована: Фев. 27, 2025
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Frontiers in Genome Editing, Год журнала: 2025, Номер 7
Опубликована: Март 18, 2025
Climate change is a global concern for agriculture, food security, and human health. It affects several crops causes drastic losses in yield, leading to severe disturbances the economy, environment, community. The consequences on important staple crops, such as rice, maize, wheat, will worsen create insecurity across globe. Although various methods of trait improvements are available being used, clustered regularly interspaced short palindromic repeats CRISPR-associated protein 9 (CRISPR/Cas9) mediated genome manipulation have opened new avenue functional genomics crop improvement. This review discuss progression improvement from conventional breeding advanced editing techniques how CRISPR/Cas9 technology can be applied enhance tolerance main cereal (wheat, maize) against any harsh climates. CRISPR/Cas endonucleases their derived genetic engineering tools possess high accuracy, versatile, more specific, easy design, climate-smart or resilient combat survive environments. CRISPR/Cas9-mediated approach has been make them climate resilient. review, supported by bibliometric analysis recent literature, highlights potential target genes/traits addresses significance gene technologies tackling vulnerable effects major maize.
Язык: Английский
Процитировано
0Biochemical and Biophysical Research Communications, Год журнала: 2024, Номер 742, С. 151084 - 151084
Опубликована: Ноя. 27, 2024
Язык: Английский
Процитировано
2Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
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