Photoelectrochemical Sensing Strategies for Cardiovascular Biomarkers: A Review

International Journal of Electrochemical Science, Год журнала: 2024, Номер unknown, С. 100906 - 100906

Опубликована: Ноя. 1, 2024

Язык: Английский

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Distinction of Male and Female Trees of Ginkgo biloba Using LAMP

Molecular Biotechnology, Год журнала: 2023, Номер 65(10), С. 1693 - 1703

Опубликована: Фев. 6, 2023

Язык: Английский

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Antitumor activity of bengamide ii in a panel of human and murine tumor cell lines: In vitro and in vivo determination of effectiveness against lung cancer

Biomedicine & Pharmacotherapy, Год журнала: 2023, Номер 168, С. 115789 - 115789

Опубликована: Ноя. 2, 2023

Lung cancer is the most commonly diagnosed and one that causes deaths worldwide, so there a need for therapies improve survival rates. Products derived from marine organisms are source of novel potent antitumor compounds, but they present great obstacle their obtaining natural environment problems associated with synthesis biological effects chemical analogues. In this work, Bengamide analogue (Bengamide II) was chemically synthesized in vitro vivo studies were performed to determine its activity mechanisms action. It shown have antiproliferative lung lines 2D 3D models. addition, II-treated cells showed G2/M G0/G1 cell cycle arrest, together decrease proliferation marker Ki67. As mechanism action, treatment increased LC3-II expression production acidic vesicles signaling autophagy. II caspase-3 activation DNA fragmentation related apoptosis. Furthermore, reduction VEGFA expression, angiogenesis, also observed. markedly reduced tumor volume metastases increasing survival. Additionally, it revealed no systemic toxicity models at therapeutic doses used, which essential future clinical use. Taken together, bengamide II, promising drug showing relevant significant safety.

Язык: Английский

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Bioimage Informatics

Elsevier eBooks, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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Advanced biosensing technologies for cardiac troponin I Detection: Challenges and future directions in personalized heart health management

Microchemical Journal, Год журнала: 2024, Номер unknown, С. 112462 - 112462

Опубликована: Дек. 1, 2024

Язык: Английский

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