A Compressive Review on Source, Toxicity and Biological Activity of Flavonoid DOI
Bhoopendra Singh, Bhupesh Chander Semwal

Current Topics in Medicinal Chemistry, Год журнала: 2024, Номер 24(24), С. 2093 - 2116

Опубликована: Авг. 7, 2024

Flavonoids are biologically active chemicals in various fruits, plants, vegetables, and leaves, which have promising uses medicinal science. The health properties of these natural widely accepted, efforts underway to extract the specific components referred as flavonoids. demonstrate a diverse range bio-activities, anticancer, antioxidant activity, anti-cholinesterase antiinflammatory antimalarial antidiabetic neurodegenerative disease, cardiovascular effect, hepatoprotective effects, antiviral antimicrobial activity. This study aims examine prevailing trends flavonoid investigation studies, elucidate activity flavonoids, their functions uses, assess potential flavonoids preventive medications for chronic diseases, outline future research opportunities this field. review explores preventing managing diseases.

Язык: Английский

Rabdosia rubescens (Hemsl.) H. Hara: A Potent Anti-Tumor Herbal Remedy - Botany, Phytochemistry, and Clinical Breakthroughs DOI
Shiyong Gao,

Li JianWen,

Weiya Wang

и другие.

Journal of Ethnopharmacology, Год журнала: 2024, Номер 340, С. 119200 - 119200

Опубликована: Дек. 3, 2024

Язык: Английский

Процитировано

26

Therapeutic potential of flavonoids in gastrointestinal cancer: Focus on signaling pathways and improvement strategies (Review) DOI Creative Commons

Ye Ding,

Yong Yu

Molecular Medicine Reports, Год журнала: 2025, Номер 31(4), С. 1 - 34

Опубликована: Фев. 24, 2025

Flavonoids are a group of polyphenolic compounds distributed in vegetables, fruits and other plants, which have considerable antioxidant, anti‑tumor anti‑inflammatory activities. Several types gastrointestinal (GI) cancer the most common malignant tumors world. A large number studies shown that flavonoids inhibitory effects on cancer, they recognized as class potential drugs. Therefore, present review investigated molecular mechanisms treatment different GI summarized drug delivery systems commonly used to improve their bioavailability. First, classification therapeutic various human diseases were briefly introduced. Then, clarify mechanism action body, metabolic process body associated signaling pathways causing five discussed, well corresponding targets flavonoids. Finally, clinical settings, poor water solubility, low permeability inferior stability, lead absorption efficiency vivo. three widely summarized. Suggestions for improving bioavailability focus next stage research also put forward.

Язык: Английский

Процитировано

1

Isoorientin: Unveiling the hidden flavonoid's promise in combating cancer development and progression – A comprehensive review DOI Creative Commons
Lucas Fornari Laurindo, Karina Torres Pomini,

Enzo Pereira de Lima

и другие.

Life Sciences, Год журнала: 2024, Номер unknown, С. 123280 - 123280

Опубликована: Ноя. 1, 2024

Язык: Английский

Процитировано

5

A Compressive Review on Source, Toxicity and Biological Activity of Flavonoid DOI
Bhoopendra Singh, Bhupesh Chander Semwal

Current Topics in Medicinal Chemistry, Год журнала: 2024, Номер 24(24), С. 2093 - 2116

Опубликована: Авг. 7, 2024

Flavonoids are biologically active chemicals in various fruits, plants, vegetables, and leaves, which have promising uses medicinal science. The health properties of these natural widely accepted, efforts underway to extract the specific components referred as flavonoids. demonstrate a diverse range bio-activities, anticancer, antioxidant activity, anti-cholinesterase antiinflammatory antimalarial antidiabetic neurodegenerative disease, cardiovascular effect, hepatoprotective effects, antiviral antimicrobial activity. This study aims examine prevailing trends flavonoid investigation studies, elucidate activity flavonoids, their functions uses, assess potential flavonoids preventive medications for chronic diseases, outline future research opportunities this field. review explores preventing managing diseases.

Язык: Английский

Процитировано

4