The effect of replacing grains with quinoa on cardiometabolic risk factors and liver function in patients with non-alcoholic fatty liver: a randomized-controlled clinical trial

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Март 3, 2025

Purpose Quinoa is a food containing dietary fiber and various phytochemicals with high nutritional value, which has structure similar to whole grains. This randomized controlled trial aimed assess the effect of substituting grains quinoa on cardiovascular risk factors liver function in individuals Non-alcoholic fatty disease (NAFLD). Methods Forty-six participants were randomly assigned either control group, maintained their regular grain-based diet, or an intervention where replaced for 12 weeks. Participants group instructed substitute during lunch The primary outcome was changes Controlled Attenuation Parameter (CAP) score between groups. Secondary outcomes included difference cardiometabolic two Results Following weeks quinoa, significant reduction weight, waist circumferences (WC) observed compared ( p value < 0.05). Furthermore, even after adjustment weight change, there CAP score, serum levels low-density lipoprotein cholesterol (LDL-C), improvement homeostatic model assessment insulin resistance (HOMA-IR) However, no other measured parameters, including enzymes, fibroscan, fasting plasma glucose, total (TC), high-density (HDL-C), inflammatory factors. Conclusion study demonstrated that replacing led HOMA-IR, LDL-C NAFLD, regardless any changes. Thus, incorporating quinoa—a plentiful low-cost source bioactive compounds—into diets NAFLS patients as staple could improve several these individuals. Clinical Trial Registration IRCT20100524004010N37.

Язык: Английский

Effect of pH and concentration on physicochemical, adsorption kinetics and rheology properties of quinoa protein: Functional correlations

JCIS Open, Год журнала: 2025, Номер unknown, С. 100131 - 100131

Опубликована: Март 1, 2025

Язык: Английский