npj Digital Medicine,
Год журнала:
2024,
Номер
7(1)
Опубликована: Авг. 10, 2024
Artificial
intelligence
(AI)
has
been
extensively
researched
in
medicine,
but
its
practical
application
remains
limited.
Meanwhile,
there
are
various
disparities
existing
AI-enabled
clinical
studies,
which
pose
a
challenge
to
global
health
equity.
In
this
study,
we
conducted
an
in-depth
analysis
of
the
geo-economic
distribution
159
as
well
gender
among
these
studies.
We
aim
reveal
from
literature
perspective,
thus
highlighting
need
for
equitable
access
medical
AI
technologies.
Nutrients,
Год журнала:
2024,
Номер
16(7), С. 990 - 990
Опубликована: Март 28, 2024
Background:
Microalgae
like
Phaeodactylum
tricornutum
(PT)
contain
the
carotenoid,
fucoxanthin,
which
has
been
purported
to
promote
fat
loss,
lower
blood
lipids,
and
improve
glucose
management.
This
study
examined
whether
dietary
supplementation
with
microalgae
extracts
from
PT
containing
4.4
mg/d
of
fucoxanthin
affects
changes
in
body
composition
or
health
markers
overweight
women
during
an
exercise
diet
intervention.
Materials
Methods:
A
total
37
females
(28.6
±
7.9
years,
80.2
14.9
kg,
29.6
3.8
kg/m²,
41.4
4.2%
fat)
fasted
for
12
h,
donated
a
fasting
sample,
completed
mood
state
inventories,
undertook
composition,
health,
assessments.
In
counterbalanced,
randomized,
double-blind
manner,
participants
ingested
placebo
(PL),
extract
standardized
mg
(FX)
weeks
while
participating
supervised
program
that
included
resistance-training
walking
(3
days/week)
encouragement
accumulate
10,000
steps/day
on
remaining
days
week.
The
intervention
involved
reducing
energy
intake
by
about
−300
kcal/d
(i.e.,
≈1400–1600
kcals/d,
55%
carbohydrate,
30%
fat,
15%
protein)
−500
deficit
exercise.
Follow-up
testing
was
performed
at
6
weeks.
general
linear
model
(GLM)
repeated
measures
statistical
analysis
used
analyze
group
responses
baseline
95%
confidence
intervals.
Results:
Dietary
did
not
additional
weight
loss
but
otherwise
healthy
initiating
designed
modest
loss.
However,
preserved
bone
mass,
increased
density,
saw
greater
improvements
steps/day,
resting
heart
rate,
aerobic
capacity,
lipid
profiles,
adherence
goals,
functional
activity
tolerance,
quality
life.
Consequently,
there
appears
be
some
benefit
supplementing
program.
Registered
clinical
trial
#NCT04761406.
Journal of Translational Medicine,
Год журнала:
2024,
Номер
22(1)
Опубликована: Окт. 19, 2024
Abstract
Background
Considering
differences
in
body
composition
and
inflammatory
status
between
sexes,
as
well
recent
recommendations
advocating
for
personalized
dietary
approaches,
this
study
aimed
to
explore
how
sex
influences
weight
loss,
changes
composition,
subjects
with
grade
I
II
obesity
undergoing
a
45-day
of
the
Very
Low-Energy
Ketogenic
Therapy
(VLEKT).
Methods
Participants
(21
premenopausal
females
21
males),
included
adhered
VLEKT
underwent
assessments
anthropometric
parameters
(weight,
height,
mass
index—BMI
–,
waist
circumference),
via
bioelectrical
impedance
analysis,
measured
by
high
sensitivity
C-reactive
protein
(hs-CRP)
levels
at
baseline
post-intervention.
Results
At
baseline,
males
did
not
differ
BMI
(
p
=
0.100)
hs-CRP
0.948).
Males
demonstrated
overall
larger
benefits
than
from
terms
loss
(Δ%
−
11.63
±
1.76
vs
8.95
1.65
kg,
<
0.001),
fat
30.84
12.00
-21.36
4.65
0.002),
41.42
21.35
22.38
17.30
mg/L,
0.003).
Of
interest,
phase
angle
values
are
statistically
improved
compared
female
17.11
9.00
7.05
3.30°,
0.001).
Conclusion
These
findings
underscore
importance
considering
sex-specific
responses
treatment
strategies,
particularly
interventions
like
VLEKTs.
Graphical
Frontiers in Public Health,
Год журнала:
2024,
Номер
11
Опубликована: Янв. 8, 2024
Objective
Analyzing
the
association
between
sociodemographic
status
and
type
2
diabetes
mellitus
(T2DM)-related
risks
in
China
to
reduce
disease
burden
of
T2DM.
Methods
We
downloaded
data
from
Global
Burden
Disease
Study
2019
estimate
T2DM
China.
Secondary
analyses
were
performed
by
year,
age,
gender,
summary
exposure
value
(SEV),
index
(SDI).
Results
In
China,
it
is
estimated
that
3.74
(3.44–4.10)
million
incidence,
90.0
(82.3–98.5)
prevalence,
168.4
(143.2–194.0)
thousand
deaths,
9.6
(7.6–11.9)
DALYs
occurred
2019,
showing
an
increase
96.8,
156.7,
162.8,
145.4%
compared
1990.
An
inverse
U-shaped
curve
was
observed
for
correlations
T2DM-related
SDI.
A
heavier
found
males.
The
top
four
risk
factors
high
body
mass
(HBMI),
dietary
risks,
air
pollution
tobacco.
HBMI,
as
key
risk,
accounted
half
Lower
degree
SEV
higher
level
attributable
could
be
main
meaning
their
critical
role
them
development
progression
age-standardized
mortality,
rate,
Conclusion
has
rapidly
increased
Gender
disparities,
different
age
distributions
inconsistent
socioeconomic
levels
all
played
important
it.
HBMI.
With
improvement
level,
have
changed
environmental
lifestyle
factors.
Targeted
control
preventative
strategies
address
adjustable
put
end
this
soaring
burden.
npj Digital Medicine,
Год журнала:
2024,
Номер
7(1)
Опубликована: Авг. 10, 2024
Artificial
intelligence
(AI)
has
been
extensively
researched
in
medicine,
but
its
practical
application
remains
limited.
Meanwhile,
there
are
various
disparities
existing
AI-enabled
clinical
studies,
which
pose
a
challenge
to
global
health
equity.
In
this
study,
we
conducted
an
in-depth
analysis
of
the
geo-economic
distribution
159
as
well
gender
among
these
studies.
We
aim
reveal
from
literature
perspective,
thus
highlighting
need
for
equitable
access
medical
AI
technologies.
