Eating- and Weight-Related Disorders in the Armed Forces DOI Creative Commons
Hubertus Himmerich, Davide Gravina, Inga Schalinski

и другие.

Metabolites, Год журнала: 2024, Номер 14(12), С. 667 - 667

Опубликована: Дек. 1, 2024

Background/Objectives: Like in the general population, prevalences of eating- and weight-related health issues armed forces are increasing. Relevant medical conditions include eating disorders (EDs) anorexia nervosa, bulimia binge disorder, avoidant restrictive food intake disorder (ARFID), as well body dysmorphic muscle dysmorphia, relative energy deficiency sport (RED-S) syndrome. Methods: We performed a narrative literature review on forces. Results: Entry standards might exclude people with obesity, EDs, or at high risk for EDs from entering military reasons to protect individual’s health. potential factors emphasis appearance fitness military, levels stress, sexual trauma, post-traumatic stress deployment, relocation, long commutes, consumption ultra-processed foods beverages, limitations selection physical exercise, intensive combat training field exercises. Eating- negatively impact professional lead problems cardiorespiratory neuromuscular fitness; daytime sleepiness; higher musculoskeletal injuries, other mental problems. Current future therapeutic options occupational measures, psychosocial therapies, neuromodulation, drug treatments. Conclusions: Even though randomized controlled trials (RCTs) have been test treatments obesity forces, RCTs treatment RED-S syndrome lacking context.

Язык: Английский

Resting-state functional brain connectivity in female adolescents with first-onset anorexia nervosa DOI Creative Commons
Katrien Bracké,

Laura Dias,

Marja van Meijer

и другие.

NeuroImage Clinical, Год журнала: 2025, Номер unknown, С. 103745 - 103745

Опубликована: Янв. 1, 2025

Women with anorexia nervosa (AN) have been shown to demonstrate differences in functional connectivity brain regions associated cognitive control, somatosensory processing, and emotion regulation. However, previous studies conducted on small samples inconsistent findings. Therefore, this study aimed identify aberrant networks related the core clinical symptoms of AN explore longitudinal association outcome a large population adolescents experiencing their first episode AN. Functional MRI (fMRI) resting-state (RS-FC) female first-onset (n = 56) were compared age- education-matched typically developing (TD) 64). To account for severity underweight, separate analyses performed investigate RS-FC between underweight participants TD adolescents, as well 30) weight-restored 26) participants. Clinical outcomes, i.e. body mass index eating disorder (ED) symptoms, assessed at baseline one-year follow-up. Independent component (ICA) used extract interest: default mode (DMN), left right frontoparietal (FPN), insular (IN) networks. Linear regression assess participants, whether was Two statistical models used: model 1 adjusted age socioeconomic status (SES), 2 additionally anxiety depressive symptoms. Underweight had lower DMN-IN, FPN-IN adolescents. After correction multiple testing, no significant found whole group group. not nor is changes DMN-IN during state. These longer observed emphasizing impact Changes these may partly explain impaired control difficulties behavioral regulation individuals

Язык: Английский

Процитировано

0
Hunger Games: A Modern Battle Between Stress and Appetite DOI Open Access

W. G. Smith,

Estefania P. Azevedo

Journal of Neurochemistry, Год журнала: 2025, Номер 169(2)

Опубликована: Фев. 1, 2025

ABSTRACT Stress, an evolutionarily adaptive mechanism, has become a pervasive challenge in modern life, significantly impacting feeding‐relevant circuits that play role the development and pathogenesis of eating disorders (EDs). Stress activates hypothalamic–pituitary–adrenal (HPA) axis, disrupts specific neural circuits, dysregulates key brain regions, including hypothalamus, hippocampus, lateral septum. These particular structures are interconnected integrating stress feeding signals, modulating hunger, satiety, cognition, emotional coping behaviors. Here we discuss interplay between genetic predispositions environmental factors may exacerbate ED vulnerability. We also highlight most commonly used animal models to study mechanisms driving EDs recent rodent studies emphasize discovery novel cellular molecular signals within hippocampus–lateral septum–hypothalamus axis. In this review, gut microbiome, emerging area research field unanswered questions persist hinder scientific progress, such as why some individuals remain resilient while others at high risk for EDs. finally need future delineating impact stressors on clarifying relevance functionality hippocampal–septal–hypothalamic connectivity, investigating neuropeptides CRH, oxytocin, GLP‐1 human pathogenesis. Emerging tools like single‐cell sequencing advanced imaging could uncover circuit‐level changes areas relevant patients. Ultimately, by basic clinical research, science offers promising avenues developing personalized, mechanism‐based treatments targeting maladaptive behavior patients suffering from image

Язык: Английский

Процитировано

0
Eating- and Weight-Related Disorders in the Armed Forces DOI Creative Commons
Hubertus Himmerich, Davide Gravina, Inga Schalinski

и другие.

Metabolites, Год журнала: 2024, Номер 14(12), С. 667 - 667

Опубликована: Дек. 1, 2024

Background/Objectives: Like in the general population, prevalences of eating- and weight-related health issues armed forces are increasing. Relevant medical conditions include eating disorders (EDs) anorexia nervosa, bulimia binge disorder, avoidant restrictive food intake disorder (ARFID), as well body dysmorphic muscle dysmorphia, relative energy deficiency sport (RED-S) syndrome. Methods: We performed a narrative literature review on forces. Results: Entry standards might exclude people with obesity, EDs, or at high risk for EDs from entering military reasons to protect individual’s health. potential factors emphasis appearance fitness military, levels stress, sexual trauma, post-traumatic stress deployment, relocation, long commutes, consumption ultra-processed foods beverages, limitations selection physical exercise, intensive combat training field exercises. Eating- negatively impact professional lead problems cardiorespiratory neuromuscular fitness; daytime sleepiness; higher musculoskeletal injuries, other mental problems. Current future therapeutic options occupational measures, psychosocial therapies, neuromodulation, drug treatments. Conclusions: Even though randomized controlled trials (RCTs) have been test treatments obesity forces, RCTs treatment RED-S syndrome lacking context.

Язык: Английский

Процитировано

0