Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults DOI Open Access

Amanda Andrade,

Tânia Nascimento, Catarina Cabrita

и другие.

Healthcare, Год журнала: 2024, Номер 12(13), С. 1275 - 1275

Опубликована: Июнь 26, 2024

Institutionalized older adults often face complex medication regimens, increasing their risk of adverse drug events due to polypharmacy, overprescribing, interactions, or the use Potentially Inappropriate Medications (PIM). However, data on and associated risks in this population remain scarce. This pilot study aimed characterize sociodemographic, clinical pharmacotherapeutic profiles, PIM among institutionalized elders residing Residential Structures for Elderly People (ERPI) Faro municipality, located Portuguese region Algarve. We conducted a cross-sectional non-randomized sample 96 participants (mean age: 86.6 ± 7.86 years) where trained researchers reviewed profiles identified potentially inappropriate medications using EU(7)-PIM list. Over 90% exhibited polypharmacy (≥5 medications), with an average 9.1 4.15 per person. About 92% had potential including major moderate interactions. More than 86% used at least one medication, most commonly central nervous system drugs. demonstrates that may be high medication-related problems. Implementing comprehensive review programs promoting adapted prescribing practices are crucial optimize improve well-being vulnerable population.

Язык: Английский

International Deprescribing Guidelines Did Not Impact Actual Practice in Deprescribing of Potentially Inappropriate Medications for Nursing Home Residents: An Interrupted Time Series Analysis DOI
Degefaye Zelalem Anlay, Kristel Paque,

Bart Van den Eynden

и другие.

Drugs & Aging, Год журнала: 2025, Номер unknown

Опубликована: Март 20, 2025

Язык: Английский

Процитировано

0
Generating and translating evidence for safe and effective medication management in aged care homes DOI Creative Commons
M. L. Annie, Amanda J. Cross, Angelita Martini

и другие.

British Journal of Clinical Pharmacology, Год журнала: 2024, Номер unknown

Опубликована: Окт. 21, 2024

Generating and translating high‐quality evidence is integral to providing safe effective medication management for residents of aged care homes. Residents are often under‐represented in trials effectiveness safety. This paper reviews opportunities challenges generating There an increasing number randomized controlled (RCTs) being conducted Observational studies can also help address the evidence‐practice gap arising from underrepresentation RCTs. Stepped‐wedge helix counterbalanced designs may overcome limitations traditional RCTs evaluating interventions setting. Strategies include building partnerships with homes organizations, using novel trial designs, leveraging existing data knowledge sharing through international platforms. quality indicators audit feedback, provision education training, engaging internal external stakeholders, development local action plans guideline implementation tools. emerging interest role brokers facilitate translation. Future directions strengthening research collaboration, industry partnerships, standardizing home support national comparisons, optimizing use technology. Initiatives improving access routinely collected administrative health conducting observational studies. should assess outcomes prioritized by ensure that strategies tailored their needs.

Язык: Английский

Процитировано

1
Potentially Inappropriate Medication: A Pilot Study in Institutionalized Older Adults DOI Open Access

Amanda Andrade,

Tânia Nascimento, Catarina Cabrita

и другие.

Healthcare, Год журнала: 2024, Номер 12(13), С. 1275 - 1275

Опубликована: Июнь 26, 2024

Institutionalized older adults often face complex medication regimens, increasing their risk of adverse drug events due to polypharmacy, overprescribing, interactions, or the use Potentially Inappropriate Medications (PIM). However, data on and associated risks in this population remain scarce. This pilot study aimed characterize sociodemographic, clinical pharmacotherapeutic profiles, PIM among institutionalized elders residing Residential Structures for Elderly People (ERPI) Faro municipality, located Portuguese region Algarve. We conducted a cross-sectional non-randomized sample 96 participants (mean age: 86.6 ± 7.86 years) where trained researchers reviewed profiles identified potentially inappropriate medications using EU(7)-PIM list. Over 90% exhibited polypharmacy (≥5 medications), with an average 9.1 4.15 per person. About 92% had potential including major moderate interactions. More than 86% used at least one medication, most commonly central nervous system drugs. demonstrates that may be high medication-related problems. Implementing comprehensive review programs promoting adapted prescribing practices are crucial optimize improve well-being vulnerable population.

Язык: Английский

Процитировано

0