Multimedia Tools and Applications, Год журнала: 2023, Номер 82(26), С. 41037 - 41072
Опубликована: Март 17, 2023
Язык: Английский
SCT Proceedings in Interdisciplinary Insights and Innovations., Год журнала: 2024, Номер 2, С. 328 - 328
Опубликована: Июнь 27, 2024
Introduction: Anemia is a public health problem that affects millions of children worldwide, especially those in the crucial stage development spans from six months to five years. Nutrition plays role prevention and treatment anemia young children. Methods: An observational, descriptive, cross-sectional study was carried out during period between January September 2023. The universe composed 50 patients ages zero years, seen consultation said center. information obtained processed through SPSS (Statistical Package for Social Sciences) version 15 system. Results: 52% sample were male 48% female. 54% range 12 2 28% 3 5 while 18% 6 11 months. 36% received breast milk until 23 months, 24% 24 22% it at time survey applied. Regarding frequency feeding, 78% fed 4 times day, on other hand, 20% day 2% day. 30% consumed eggs days old, likewise 40% ingested meat old. Conclusions: nutrition feeding pediatric patient with challenge current times. In present research, there predominance sex. age, significant percentage which their nutritional scheme
Язык: Английский
Процитировано
3
Progress in molecular biology and translational science, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Апрель 27, 2025
Abstract The safety profile of COVID-19 vaccines is well-established, yet the widespread immunization campaign has led to an increase in reported cases Immune-Mediated and Rheumatic Diseases (IMDRs). This study aimed assess reporting Adverse Events Following Immunization (AEFIs) related IMDRs after vaccination. We analyzed all individual case reports (ICSRs) authorized European Union (i.e., tozinameran, elasomeran, ChAdOx1-S NCoV-19, Ad26.Cov2.S) registered EudraVigilance (EV) database from January 1, 2021, October 23, 2023. Our analysis identified ICSRs with events indicative conducted disproportionality Reporting Odds Ratio (ROR) 95% CI) examine frequency different IMDR types linked each vaccine. In total, 45,352 at least one AEFI associated rheumatic or autoimmune conditions, 54% them implicating tozinameran as suspected More than half AEFIs were classified serious, approximately 45% remaining unresolved. most frequently conditions other immune-mediated diseases, followed by arthritis, vasculitis, systemic lupus erythematosus, tendinopathies. suggested that mRNA may be more new diseases. Stratified revealed significant associations for ChAd, particularly vasculitis tendinopathies, only when compared Ad26.Cov2.S. Real-world pharmacovigilance data suggest diseases under-reported following vaccination, highlighting need further research better understand underlying mechanisms. findings this studies investigate these results greater depth.
Язык: Английский
Процитировано
0
Journal of Controlled Release, Год журнала: 2023, Номер 357, С. 404 - 416
Опубликована: Апрель 13, 2023
Язык: Английский
Процитировано
8
European journal of medical research, Год журнала: 2023, Номер 28(1)
Опубликована: Июль 13, 2023
Global Coronavir us disease 2019 (COVID-19) vaccination efforts are being intensified to combat the pandemic. As frequency of immunization against COVID-19 has increased, some adverse effects related have emerged. Within this context, article reviewed 62 Graves' (GD) cases following vaccination, probe potential association between and onset GD. A comprehensive search PubMed, Web Science, Scopus databases was conducted collect GD up June 7, 2023. Among included in review, there were 33 (53.2%) new-onset 10 (16.1%) relapsed patients mRNA 14 (22.6%) 4 (6.5%) viral vector 1 (1.6%) inactivated vaccination. Median durations symptoms for 12 (range: 1-60) 21 5-30) days while 7 1-28) 10-14) respectively. While definitive pathogenesis remains unclear, it might be associated with cross-immune responses triggered by molecular mimicry, an adjuvant-induced autoimmune/inflammatory syndrome. However, due limited number observed lack systematic experimental studies, a causal relationship not been definitively confirmed. It should highlighted that most experienced positive outcomes after treatment. In broader context ending pandemic reducing mortality rates, benefits significantly outweigh mild risks such as treatable Adherence schedule is therefore imperative effectively managing
Язык: Английский
Процитировано
8
The Journal of Clinical Endocrinology & Metabolism, Год журнала: 2023, Номер 109(2), С. e508 - e512
Опубликована: Окт. 10, 2023
Abstract Objective Multiple cases and case series reported Graves’ disease (GD) following coronavirus 2019 (COVID-19) vaccination. We aimed to determine whether COVID-19 vaccination was associated with the incidence of GD. Methods analyzed data from Clalit Health Services, largest healthcare organization in Israel, which insures 4.7 million patients. A population-based, matched, case-control study performed. Cases were defined as adult patients diagnosed GD between December 2020 November 2022. Each matched controls a 1:2 ratio. control assigned an index date, identical that their case, date diagnosis. Time diagnosis or assessed. Results total 726 1452 controls. The have received similar proportions vaccine [at least 1 dose: 80% (581/726) vs 77.8% (1129/1452), P = .22, respectively]. In univariate analysis, at dose not [odds ratio 95% confidence interval: 1.15 (.92-1.43)]. mean time first for significantly different [275.69 days (SD 144.37) compared 275.45 145.76) controls]. Conclusion Our found no association
Язык: Английский
Процитировано
6
Diabetology International, Год журнала: 2024, Номер 15(3), С. 577 - 582
Опубликована: Фев. 29, 2024
Язык: Английский
Процитировано
2
Frontiers in Immunology, Год журнала: 2024, Номер 15
Опубликована: Июль 9, 2024
Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), long COVID (LC) and post-COVID-19 vaccine show similarities in their pathophysiology clinical manifestations. These disorders are related to viral adjuvant persistence, immunological alterations, autoimmune diseases hormonal imbalances. A developmental model is postulated that involves the interaction between immune hyperactivation, hypophysitis pituitary hypophysitis, depletion. This process might begin with a deficient CD4 T-cell response infections genetically predisposed individuals (HLA-DRB1), followed by an uncontrolled CD8 hyperactivation elevated antibody production, some of which may be directed against autoantigens, can trigger direct damage pituitary, resulting decreased production hormones, such as ACTH. As disease progresses, prolonged exposure antigens lead exhaustion system, exacerbating symptoms pathology. It suggested these could included autoimmune/adjuvant-induced inflammatory (ASIA) because similar manifestations possible relationship genetic factors, polymorphisms HLA-DRB1 gene. In addition, it proposed treatment antivirals, corticosteroids/ginseng, antioxidants, metabolic precursors improve modulating response, function, inflammation oxidative stress. Therefore, purpose this review suggest origin adenohypophysis improvement after corticosteroid replacement therapy.
Язык: Английский
Процитировано
2
International Journal of Vaccine Theory Practice and Research, Год журнала: 2023, Номер 3(1), С. 707 - 726
Опубликована: Янв. 12, 2023
Case reports involving two academic researchers suggest that adverse events (AEs) to COVID-19 messenger RNA (mRNA) vaccination are largely underreported due numerous clinical, systemic, political and media factors. The lack of proper analysis consideration the reported AEs also suggests these injections not as safe widely purported. resulting biased risk-benefit assessment may only produce misinformed public health recommendations misguided decisions, thereby exposing population an underestimated risk, in possible violation precautionary principle right a free informed consent. mechanisms underlying raise serious concerns regarding new vaccine application mRNA technology need be addressed before expanding it other infectious diseases. legal considerations AE underreporting discussed, formulated. reality better assessed than heretofore, diagnosed authorities for follow-up investigation order inform policy decisions updates physician guidelines objective, scientifically based, independent, transparent manner.
Язык: Английский
Процитировано
5
Antiviral Therapy, Год журнала: 2023, Номер 28(5)
Опубликована: Окт. 1, 2023
Background: Subacute thyroiditis (SAT) is an organ-specific disease that various drugs, including COVID-19 vaccines, can trigger. infection has been associated with thyroid gland damage and SARS-CoV-2 direct action, euthyroid sick syndrome, immune-mediated mechanisms are all potential of damage. It denotes inflammation, most commonly viral origin, belongs to the transitory, self-limiting diseases group, causing complications in approximately 15% patients form permanent hypothyroidism. Some authors say SAT common COVID-19. Purpose: The occurrence many weeks after administering second vaccine rare limited documentation academic literature. This study aims present vaccine. We case a 37-year-old man who developed 23 days receiving dose Pfizer BioNTech's mRNA Research design sample: Due neck pain elevated body temperature (up 38.2°C), male subject presented for examination BioNTech against infection. patient denied ever having autoimmune or any other disease. Painful palpation firm, slightly enlarged no surrounding lymphadenopathy were identified during exam. heart rate was 104 beats per minute. All remaining physical findings normal. Data collection and/or Analysis: collected integral medical record. Results: Hematology biochemistry analyses at initial follow-up visits revealed minor leukocytosis, normocytic anaemia, thrombocytosis, followed by mild increase lactate dehydrogenase decreased iron levels. patient's function morphology had recovered entirely from post-vaccine SAT. Conclusions: Results this emphasise need healthcare professionals promptly report related vaccination. Further investigation warranted understand immunopathogenesis COVID-19-associated impact immunization on condition.
Язык: Английский
Процитировано
5