The Effects of a Whole-Food Plant-Based Nutrition Education Program on Blood Pressure and Potassium in Chronic Kidney Disease: A Proof-of-Concept Study
Nutrients,
Год журнала:
2025,
Номер
17(5), С. 779 - 779
Опубликована: Фев. 24, 2025
Whole-food
plant-based
diets
(WFPBDs)
are
beneficial
in
managing
hypertension
the
general
population
but
have
not
been
well
studied
chronic
kidney
disease
(CKD),
potentially
due
to
concerns
about
hyperkalemia.
We
hypothesized
that
individuals
with
CKD
3
or
4
attending
a
15-day
WFPBD
education
program
would
achieve
lower
blood
pressure
compared
those
who
did
not,
without
an
increased
risk
of
This
was
pilot
trial
40
subjects
mild-to-moderate
and
diabetes
proteinuria
from
single
academic
center.
The
were
randomized
control
group.
changes
pressure,
serum
potassium,
other
anthropometric
biochemical
values
assessed.
Systolic
decreased
baseline
day
15
intervention
group
by
8
mm
Hg
2.7
Hg,
although
difference
change
reach
statistical
significance
(p
=
0.12).
Diastolic
different
between
two
groups.
Potassium
changed
0.01
mEq/L
-0.07
0.52).
had
significant
decreases
body
mass
(-3.0
vs.
-0.12
kg,
p
<
0.0001),
total
cholesterol
(-39.4
-5.0
mg/dL,
low-density
lipoprotein
(-28.4
-0.6
high-density
(-8.6
-0.4
0.006)
controls.
albumin
phosphorus
non-statistically
reduction
systolic
hyperkalemia
attend.
achieved
significantly
greater
reductions
adverse
effects
on
phosphorus.
Larger
longer-duration
trials
using
this
approach
diverse
patients
warranted.
Язык: Английский
A nutrient wide association study of cardiovascular disease prevalence in older adults from NHANES 2007 to 2018
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Апрель 13, 2025
Cardiovascular
disease
(CVD)
remains
the
leading
cause
of
mortality
worldwide,
particularly
among
older
adults.
Identifying
modifiable
dietary
factors
associated
with
CVD
prevalence
is
essential
for
prevention.
This
cross-sectional
study
analyzed
7,341
adults
aged
≥
65
years
from
NHANES
2007-2018.
was
defined
based
on
self-reported
physician-diagnosed
conditions,
including
coronary
heart
disease,
failure,
angina,
attack,
or
stroke.
A
nutrient-wide
association
(NWAS)
evaluated
associations
between
56
nutrients
and
using
multivariable
logistic
regression.
Dose-response
relationships
were
assessed
restricted
cubic
spline
(RCS)
models.
Model
discrimination
receiver
operating
characteristic
(ROC)
analysis.
Eight
significantly
after
adjusting
confounders
correcting
multiple
comparisons:
PUFAs
20:4
(OR
0.88,
95%
CI
0.80-0.97,
P
=
0.024),
22:5
0.72,
0.56-0.92,
0.019),
22:6
0.92,
0.87-0.99,
0.032);
total
choline
0.96,
0.93-0.99,
0.024);
cholesterol
0.89,
0.82-0.96,
0.037);
protein
0.82,
0.76-0.89,
0.040);
vitamin
0.95,
0.91-0.99,
0.045);
sugars
0.97,
0.96-0.98,
0.049).
Clustering
analysis
identified
protective
effects
fat-soluble
vitamins
unsaturated
fatty
acids.
The
inclusion
these
improved
model
(P
<
0.05).
key
clusters
characterized
their
dose-response
relationships.
Integrating
into
predictive
models
enhances
risk
discrimination,
providing
actionable
targets
prevention
strategies
in
Язык: Английский
Adherence to a healthful plant-based diet and risk of mortality among individuals with chronic kidney disease: A prospective cohort study
medRxiv (Cold Spring Harbor Laboratory),
Год журнала:
2024,
Номер
unknown
Опубликована: Апрель 10, 2024
Abstract
Background
Plant-rich
dietary
patterns
may
protect
against
negative
health
outcomes
among
individuals
with
chronic
kidney
disease
(CKD),
although
aspects
of
plant-based
diet
quality
have
not
been
studied.
This
study
aimed
to
examine
associations
between
healthful
and
unhealthful
risk
mortality
CKD
patients
for
the
first
time.
Methods
prospective
analysis
included
4,807
UK
Biobank
participants
at
baseline.
We
examined
adherence
both
index
(hPDI)
(uPDI),
calculated
from
repeated
24-hour
assessments,
using
multivariable
Cox
proportional
hazard
regression
models.
Results
Over
a
10-year
follow-up,
675
deaths
were
recorded.
Participants
highest
hPDI
scores
had
33%
lower
[HR
Q4vsQ1
(95%
CI):
0.67
(0.53-0.84),
p
trend
=
<0.001],
while
those
uPDI
49%
higher
[1.49
(1.18-1.89),
0.004],
compared
lowest
respective
following
adjustment
other
lifestyle
factors.
In
food
group-specific
analyses,
wholegrain
intakes
associated
29%
risk,
refined
grains,
sugar-sweetened
beverages
28%
31%
respectively.
Conclusions
patients,
intake
healthy
foods
was
mortality,
unhealthy
risk.
These
results
underscore
importance
plant
support
potential
role
consumption
in
treatment
management
mitigate
unfavourable
outcomes.
Язык: Английский
Adherence to a healthful plant-based diet and risk of mortality among individuals with chronic kidney disease: A prospective cohort study
Clinical Nutrition,
Год журнала:
2024,
Номер
43(10), С. 2448 - 2457
Опубликована: Сен. 12, 2024
Язык: Английский
The Effect of Antioxidant Polyphenol Supplementation on Cardiometabolic Risk Factors: A Systematic Review and Meta-Analysis
Nutrients,
Год журнала:
2024,
Номер
16(23), С. 4206 - 4206
Опубликована: Дек. 5, 2024
:
Polyphenol
is
considered
to
exert
a
favorable
impact
on
cardiovascular
health.
Язык: Английский
EXPLORING NUTRITIONAL STATUS AND LATE POST-TRANSPLANT ANATOMICAL CHANGES IN PATIENTS WITH CHRONIC KIDNEY DISEASE: A COMPREHENSIVE ANALYSIS
Опубликована: Март 27, 2024
Introduction:
Patients
undergoing
post-transplant
chronic
kidney
disease
face
a
prolonged
and
challenging
journey
in
adapting
to
the
new
organ.
Throughout
this
phase,
their
nutritional
status
is
directly
impacted
by
various
factors,
including
diet,
biochemical
measures,
lifestyle,
anthropometric
assessments.
This
information
plays
crucial
role
evaluating
well-being
of
these
individuals.
Objective:
The
study
aims
analyze
relationship
between
late
changes,
considering
factors
such
as
dietary
habits,
immunosuppressant
usage,
emergence
diseases
post-transplantation.
Method:
retrospective
cross-sectional
analytical
with
prospective
aspects
was
conducted
period.
Data,
clinical,
socioeconomic,
demographic,
anthropometric,
parameters,
were
collected
from
patients
at
clinic
Professor
Fernando
Institute
Integral
Medicine
Figueira
(IMIP/PE).
Results:
sample
comprised
32
patients,
hypertension
being
most
prevalent
associated
cardiovascular
risk,
followed
diabetes.
While
majority
exhibited
eutrophic
status,
there
an
risk
based
on
waist-to-hip
ratio,
waist-to-height
conicity
index
methods.
Food
consumption
showed
no
significant
association
developing
diseases.
Conclusion:
Nutritional
monitoring
for
preventing
short-term
post-transplantation,
contributing
improved
clinical
outcomes
reduction
complications
that
may
jeopardize
transplanted
Язык: Английский