Coordination Chemistry Reviews, Год журнала: 2023, Номер 490, С. 215211 - 215211
Опубликована: Май 12, 2023
Язык: Английский
Nanomaterials, Год журнала: 2022, Номер 12(2), С. 277 - 277
Опубликована: Янв. 16, 2022
Metal−organic frameworks (MOFs) are a novel class of porous hybrid organic−inorganic materials that have attracted increasing attention over the past decade. MOFs can be used in chemical engineering, science, and chemistry applications. Recently, these structures been thoroughly studied as promising platforms for biomedical Due to their unique physical properties, they regarded candidates disease diagnosis drug delivery. Their well-defined structure, high porosity, tunable frameworks, wide range pore shapes, ultrahigh surface area, relatively low toxicity, easy functionalization made them focus extensive research. This review highlights up-to-date progress potential delivery diseases such cancer, diabetes, neurological disorders, ocular diseases. A brief description synthesis methods is first presented. Various examples MOF-based sensors DDSs introduced different Finally, challenges perspectives discussed provide context future development efficient systems.
Язык: Английский
Процитировано
138
Journal of Materials Chemistry B, Год журнала: 2021, Номер 9(22), С. 4459 - 4474
Опубликована: Янв. 1, 2021
In the presented perspective, synthetic method, characterization, and research progress in tumor therapy based on CMMs have been summarized. Also prospects challenges of utilizing for discussed.
Язык: Английский
Процитировано
135
Chemical Society Reviews, Год журнала: 2022, Номер 51(14), С. 6065 - 6086
Опубликована: Янв. 1, 2022
This review critically evaluates the recent advancements in understanding of endocytosis nano-sized metal–organic frameworks and importance biological context aiding MOF rational design synthesis for drug delivery applications.
Язык: Английский
Процитировано
128
Biomaterials, Год журнала: 2021, Номер 281, С. 121322 - 121322
Опубликована: Дек. 15, 2021
Язык: Английский
Процитировано
125
Inorganics, Год журнала: 2022, Номер 10(11), С. 202 - 202
Опубликована: Ноя. 9, 2022
A hydrostable 2D Zn-based MOF, {[Zn(5-PIA)(imbm)]·2H2O}n (1) (5-H2PIA = 5-propoxy-isophthalic acid, imbm 1,4-di(1H-imidazol-1-yl)benzene), was synthesized and structurally characterized. Complex 1 shows good water thermal stability based on the TGA PXRD analyses displays a framework with 1D channels of 4.8 × 13.8 10.0 8.3 Å2 along axis. The 5-fluorouracil (5-FU) payload in activated complex (complex 1a) is 19.3 wt%, cumulative release value 5-FU at 120 h about 70.04% PBS (pH 7.4) 310 K. In vitro MTT assays did not reveal any cytotoxic effect NIH-3T3 HEK-293 cells when concentration below 500 μg/mL 5 μg/mL, respectively. No morphological abnormalities were observed zebrafish exposed to 1.
Язык: Английский
Процитировано
125
Nano-Micro Letters, Год журнала: 2023, Номер 15(1)
Опубликована: Фев. 16, 2023
Abstract Agro seeds are vulnerable to environmental stressors, adversely affecting seed vigor, crop growth, and productivity. Different agrochemical-based treatments enhance germination, but they can also cause damage the environment; therefore, sustainable technologies such as nano-based agrochemicals urgently needed. Nanoagrochemicals reduce dose-dependent toxicity of treatment, thereby improving viability ensuring controlled release nanoagrochemical active ingredients However, applications nanoagrochemicals plants in field raise concerns about nanomaterial safety, exposure levels, toxicological implications environment human health. In present comprehensive review, development, scope, challenges, risk assessments on treatment discussed. Moreover, implementation obstacles for use treatments, their commercialization potential, need policy regulations assess possible risks Based our knowledge, this is first time that we have presented legendary literature readers order help them gain a deeper understanding upcoming nanotechnologies may enable development future generation agrochemical formulations, potential associated with treatment.
Язык: Английский
Процитировано
117
ACS Central Science, Год журнала: 2021, Номер 7(3), С. 445 - 453
Опубликована: Фев. 11, 2021
Metal–organic frameworks (MOFs) are a class of materials which exhibit permanent porosity, high surface area, and crystallinity. As highly tunable middle ground between heterogeneous homogeneous species, MOFs have the potential to suit wide variety applications, many require conductive materials. The continued development has provided an ever-growing library with both intrinsic guest-promoted conductivity, factors limit or enhance conductivity in become more apparent. In this Outlook, believed influence future MOF most heavily highlighted along proposed methods further developing these fields. Fundamental studies derived from may provide pathways raise across range structures.
Язык: Английский
Процитировано
115
Journal of Colloid and Interface Science, Год журнала: 2023, Номер 654, С. 495 - 522
Опубликована: Окт. 14, 2023
Язык: Английский
Процитировано
108
Acta Pharmaceutica Sinica B, Год журнала: 2023, Номер 13(11), С. 4391 - 4416
Опубликована: Май 20, 2023
Owing to the inherent shortcomings of traditional therapeutic drugs in terms inadequate efficacy and toxicity clinical treatment, nanomedicine designs have received widespread attention with significantly improved reduced non-target side effects. Nanomedicines hold tremendous theranostic potential for treating, monitoring, diagnosing, controlling various diseases are attracting an unfathomable amount input research resources. Against backdrop exponentially growing number publications, it is imperative help audience get a panorama image activities field nanomedicines. Herein, this review elaborates on development trends nanomedicines, emerging nanocarriers, vivo fate safety their extensive applications. Moreover, challenges obstacles hindering translation nanomedicines also discussed. The elaboration aspects may enlighten readers set route future endeavors.
Язык: Английский
Процитировано
89
Environment International, Год журнала: 2023, Номер 175, С. 107928 - 107928
Опубликована: Апрель 11, 2023
Pharmaceutical residues are the undecomposed remains from drugs used in medical and food industries. Due to their potential adverse effects on human health natural ecosystems, they of increasing worldwide concern. The acute detection pharmaceutical can give a rapid examination quantity then prevent them further contamination. Herein, this study summarizes discusses most recent porous covalent-organic frameworks (COFs) metal–organic (MOFs) for electrochemical various residues. review first introduces brief overview drug toxicity its living organisms. Subsequently, different materials techniques discussed with materials' properties applications. Then development COFs MOFs has been addressed structural sensing Further, stability, reusability, sustainability MOFs/COFs reviewed discussed. Besides, MOFs' limits, linear ranges, role functionalities, immobilized nanoparticles analyzed Lastly, summarized [email protected] composite as sensors, fabrication strategies enhance potential, current challenges area.
Язык: Английский
Процитировано
83