View, Год журнала: 2025, Номер unknown

Опубликована: Март 16, 2025

Abstract Photocatalysts with dual functionalities of decomposing organic pollutants in water and combating bacterial infections are increasingly important. Herein, NaGdF 4 :Yb,Tm@ZnO/Ag 3 PO (UZA) nanoheterojunction photocatalysts were synthesized via hydrothermal, sol–gel, situ deposition methods. The UZA photocatalyst demonstrated exceptional efficiency generating reactive oxygen species (ROS), crucial for pollutant degradation. incorporation Ag facilitated efficient charge transfer the all‐solid‐state Z‐scheme system. Furthermore, exhibited potent antibacterial properties against both Gram‐positive Staphylococcus aureus ( S. ) Gram‐negative Escherichia coli E. ). minimum bactericidal concentrations (MBC) 50 µg/mL 25 under natural irradiation, 100 980 nm respectively. In vivo studies using a mouse model acute bacterial‐infected wounds that incorporated into chitosan hydrogel dressings accelerated wound healing through photodynamic therapy within 9 days. treated rapid reduction to 9.95% initial area, diminished inflammatory responses, enhanced re‐epithelialization attributed sustained effects pathogen inhibition. Moreover, composites showed excellent biocompatibility minimal hemolysis rate 0.5% on erythrocytes. These findings underscore promising application treatment skin caused by pathogenic bacteria.

Язык: Английский