Food Microbiology, Год журнала: 2024, Номер 124, С. 104621 - 104621
Опубликована: Авг. 17, 2024
Язык: Английский
Molecules, Год журнала: 2025, Номер 30(4), С. 863 - 863
Опубликована: Фев. 13, 2025
Natural surfactants are surface-active molecules synthesized from renewable resources (i.e., plants, animals, or microorganisms) and possess properties comparable to conventional surfactants, making them an environmentally friendly potential alternative petrochemical surfactants. Additionally, they exhibit biological such as anti-microbial properties, biodegradability, less toxicity, allowing their use in everyday products with minimal risk human health the environment. Based on mode of production, natural can be classified into first-generation bio-based second-generation biosurfactants, although definition may vary depending author literature. This review offers extensive classification focusing composition, sources, production methods, applications across various industries. Furthermore, main challenges future perspectives discussed.
Язык: Английский
Процитировано
2
Microbiological Research, Год журнала: 2025, Номер 293, С. 128054 - 128054
Опубликована: Янв. 7, 2025
Язык: Английский
Процитировано
1
Foods, Год журнала: 2025, Номер 14(2), С. 207 - 207
Опубликована: Янв. 10, 2025
Lipopeptides (LPs) are widely sourced surface-active natural products with a wide range of functions and low toxicity, high potency, good biodegradability. In this paper, we summarize, for the first time, plant, animal, microbial, synthetic sources LPs. We also introduce applications LPs in food human health, including (1) can inhibit growth microorganisms during production preservation. They be added to packaging materials preservation freshness transportation, used as additives improve taste food. (2) provide amino acids promote protein synthesis cellular repair. Due their broad-spectrum antimicrobial properties, they exhibit anticancer effects biological activities. This review summarizes, laying foundation development application
Язык: Английский
Процитировано
1
Current Research in Microbial Sciences, Год журнала: 2024, Номер 7, С. 100266 - 100266
Опубликована: Янв. 1, 2024
Pesticide pollution remains a significant environmental challenge, necessitating the exploration of sustainable alternatives. Biosurfactants are class unconventional surface-active chemicals that produced by microorganisms. have many applications in treating oil spills, emulsifiers, pharmaceuticals, and agriculture. Compared to chemical surfactants, they benefits such as biodegradability, less toxicity, greener option because derived from microbes. recently been shown potential speed up pesticide cleanup. used remediation their exceptional foaming ability, high selectivity, wide range pH, salinity, temperature operating windows. Microbial biosurfactants emerged agents for treatment organic waste agricultural residue. This review unfolds promising realm microbial green solutions sustainability, particularly practices, with special reference remediation. article highlights escalating need eco-friendly alternatives, paving way discussing biosurfactants. Moreover, articles discuss detail various advancements field rapid screening biosurfactants, either using conventional approach or
Язык: Английский
Процитировано
7
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(1), С. 336 - 336
Опубликована: Янв. 2, 2025
Bacillus cyclic lipopeptides (CLP), part of the three main families—surfactins, iturins, and fengycins—are secondary metabolites with a unique chemical structure that includes both peptide lipid components. Being amphiphilic compounds, CLPs exhibit antimicrobial activity in vitro, damaging membranes microorganisms. However, concentrations used vitro are difficult to achieve natural conditions. Therefore, environment, alternative mechanisms action by more likely, such as inducing apoptosis fungal cells, preventing microbial adhesion substrate, promoting death phytopathogens stimulating plant immune responses. In addition, low act signaling molecules Bacillus’s own metabolism, when environmental conditions change, they form an adaptive response host bacterium. Namely, trigger differentiation bacterial population into various specialized cell types: competent flagellated matrix producers, spores. this review, we have summarized current understanding under experimental We also shown relationship between some regulatory pathways involved CLP biosynthesis differentiation, well role determine changes physiological state subpopulations shifts
Язык: Английский
Процитировано
1
Microbiological Research, Год журнала: 2024, Номер 288, С. 127841 - 127841
Опубликована: Авг. 2, 2024
In the prospect of novel potential biocontrol agents, a new strain BDI-IS1 belonging to recently described Bacillus nakamurai was selected for its strong in vitro antimicrobial activities against range bacterial and fungal phytopathogens. Genome mining coupled with metabolomics revealed that produces multiple non-ribosomal secondary metabolites including surfactin, iturin A, bacillaene, bacillibactin bacilysin, together some ribosomally-synthesized post-translationally modified peptides (RiPPs) such as plantazolicin, potentially amylocyclicin, bacinapeptin LCI. Reverse genetics further showed specific involvement these compounds antagonistic activity strain. Comparative genomics between five already sequenced B. strains products constitute core metabolome species while RiPPs are more strain-specific. Although lacks key bioactive found velezensis, greenhouse experiments show is able protect tomato maize plants early blight northern leaf caused by Alternaria solani Exserohilum turcicum, respectively, at levels similar or better than velezensis QST713. The reduction foliar diseases, following root application suspension demonstrates can act direct antibiosis inducing plant defence mechanisms. These findings indicate be considered good candidate diseases prevailing tropical regions, encourage research into spectrum activity, requirements conditions needed ensure efficacy.
Язык: Английский
Процитировано
6
Fungal Biology, Год журнала: 2024, Номер 128(7), С. 2080 - 2088
Опубликована: Авг. 15, 2024
Bacillus spp. produce numerous antimicrobial metabolites. Among these metabolites, cyclic lipopeptides (CLP) including fengycins, iturins, and surfactins are known to have varying antifungal activity against phytopathogenic fungi. The differential activities of CLP been attributed diverse mechanisms action on fungal membranes. However, the precise biochemical determinants driving their modes not conclusively identified. In this study, three plant pathogenic fungi lipopeptide sensitivities, Alternaria solani, Cladosporium cucumerinum, Fusarium sambucinum, were studied determine how cell membrane lipid compositions may confer sensitivity and/or tolerance fengycin, iturin, surfactin. Results indicated that all correlated with lower ergosterol content elevated phospholipid fatty acid unsaturation. Fungal surfactin was also notably different than fengycin as influenced more by phosphatidylethanolamine amounts, higher levels phosphatidylinositol, less acyl chain length. from study provide insight into composition A. F. C. cucumerinum specific characteristics influencing effectiveness Understanding should enable accurate prediction sensitivity-tolerance outcomes for other species exposed important CLP.
Язык: Английский
Процитировано
4
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 271, С. 132545 - 132545
Опубликована: Май 28, 2024
Язык: Английский
Процитировано
3
Journal of Fungi, Год журнала: 2025, Номер 11(3), С. 207 - 207
Опубликована: Март 6, 2025
Sorghum (Sorghum bicolor L.) is a globally important energy and food crop that becoming increasingly integral to security the environment. However, its production significantly hampered by various fungal phytopathogens affect yield quality. This review aimed provide comprehensive overview of major affecting sorghum, their impact, current management strategies, potential future directions. The diseases covered include anthracnose, grain mold complex, charcoal rot, downy mildew, rust, with an emphasis on pathogenesis, symptomatology, overall economic, social, environmental impacts. From initial use fungicides shift biocontrol, rotation, intercropping, modern tactics breeding resistant cultivars against mentioned are discussed. In addition, this explores disease management, particular focus role technology, including digital agriculture, predictive modeling, remote sensing, IoT devices, in early warning, detection, management. It also key policy recommendations support farmers advance research thus emphasizing need for increased investment research, strengthening extension services, facilitating access necessary inputs, implementing effective regulatory policies. concluded although pose significant challenges, combined effort innovative policies can mitigate these issues, enhance resilience sorghum facilitate global issues.
Язык: Английский
Процитировано
0
Journal of Natural Products, Год журнала: 2025, Номер unknown
Опубликована: Март 26, 2025
Fengycin is an antifungal drug that could be used as a biocontrol agent if it produced in high amounts. The ComQXPA quorum sensing (QS) system natural mechanism, regulating cell density-dependent behaviors Bacillus subtilis. This study employed the QS-targeted promoter PsrfA to express pps gene cluster B. subtilis, coupling produce fengycin. Mutations ComA regulatory protein-binding site RE3 exhibited 2.45-fold increase expression intensity and resulted elevation of fengycin production from 489 1832 mg/L, 2.74-fold enhancement. Transcriptomic analysis revealed upregulation genes associated with carbon source uptake utilization metabolic pathways related amino acids fatty acids, which are precursors for synthesis. Additionally, knockout rapJ rapE increased 3190 mg/L. In coculture constructed Corynebacterium glutamicum, reached 4005 work provides strategy dynamically
Язык: Английский
Процитировано
0