Biomarker Research, Год журнала: 2025, Номер 13(1)

Опубликована: Апрель 18, 2025

Abstract Angiogenesis, a crucial process in tumor growth and metastasis, necessitates targeted therapeutic intervention. This review reviews the latest knowledge of anti-angiogenesis targets tumors, with emphasis on molecular mechanisms signaling pathways that regulate this process. We emphasize microenvironment's role angiogenesis, examine endothelial cell metabolic changes, evaluated potential strategies targeting vascular system. At same time, we analyzed pathway mechanism angiogenesis detail. In addition, paper also looks at development trend drugs, including their future direction challenges, aiming to provide prospective insight into field. Despite potential, anti-angiogenic therapies encounter challenges like drug resistance side effects, necessitating ongoing research enhance cancer treatment efficacy these therapies.

Язык: Английский