Efficacy of ultraviolet-light emitting diodes in bacterial inactivation and DNA damage via sensitivity evaluation using multiple wavelengths and bacterial strains

Archives of Microbiology, Год журнала: 2025, Номер 207(6)

Опубликована: Апрель 25, 2025

Ultraviolet-light emitting diodes (UV-LEDs) have garnered attention for their efficient bacterial inactivation. However, in previous studies, it has been difficult to strictly compare the inactivation effect of UV irradiation among wavelengths differing by a few nanometers because detailed conditions comparison, such as LED characteristics at each wavelength and power supply characteristics, not established. Therefore, this study aimed evaluate 10 strains across 13 (250-365 nm) using standardized system previously reported identify most effective prevention infection contamination. Bacterial dose response curves were generated determine fluence required archive 1-3 log10 The results indicated that Gram-negative bacteria exhibited higher initial sensitivity compared with Gram-positive bacteria. Wavelength-dependent peaked 263-270 nm, correlating strongly cyclobutane pyrimidine dimer production (r > 0.9 strains). Deconvolution analysis confirmed inhibition was maximal around 267.6 nm. Furthermore, UV-LEDs outperformed low-pressure mercury lamps terms under equivalent fluences, attributed differences spectral emission profiles. These findings will help optimize UV-LED sterilization methods broader applications microbial control.

Язык: Английский

UV-C treatment has a higher efficacy on reducing germination of spores rather than mycelium growth

European Journal of Plant Pathology, Год журнала: 2025, Номер unknown

Опубликована: Май 7, 2025

Язык: Английский