Bringing Lab to the Field: Exploring Innovations in Point-of-Care Diagnostics for the Rapid Detection and Management of Tropical Diseases in Resource-Limited Settings
Advances in Biomarker Sciences and Technology,
Год журнала:
2025,
Номер
unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Neonatal Infectious Disease: A Major Contributor to Infant Mortality Requiring Advances in Point-of-Care Diagnosis
Antibiotics,
Год журнала:
2024,
Номер
13(9), С. 877 - 877
Опубликована: Сен. 13, 2024
Neonatal
infectious
disease
continues
to
result
in
high
rates
of
infant
morbidity
and
mortality.
Early-
late-onset
represent
difficult
detect
treat
illnesses,
particularly
when
antimicrobial
resistant
pathogens
are
present.
Newborns
immunodeficient
at
increased
risk
vertical
horizontal
infection,
with
preterm
infants
increasingly
susceptible.
Additional
factors
associated
infection
include
prolonged
use
a
central
catheter
and/or
ventilation,
congenital
abnormalities,
admittance
intensive
care
units,
the
broad-spectrum
antibiotics.
There
is
increasing
recognition
importance
host
microbiome
dysbiosis
on
neonatal
disease,
including
necrotising
enterocolitis
sepsis
patients.
Current
diagnostic
methods
rely
blood
culture,
which
unreliable,
time
consuming,
can
false
negatives.
lack
accurate
reliable
tools
available
for
early
detection
infants;
therefore,
efficient
triage
treatment
remains
challenging.
The
application
biomarkers,
machine
learning,
artificial
intelligence,
biosensors,
microfluidics
technology,
may
offer
improved
methodologies.
Point-of-care
devices,
such
methodologies,
provide
fast,
reliable,
aids
This
review
will
discuss
as
impacted
by
resistance
highlight
novel
point-of-care
options.
Язык: Английский
Antimicrobial Resistance Patterns and Biofilm Analysis via Sonication in Intensive Care Unit Patients at a County Emergency Hospital in Romania
Pharmaceuticals,
Год журнала:
2025,
Номер
18(2), С. 161 - 161
Опубликована: Янв. 25, 2025
Background/Objectives:
Ventilator-associated
pneumonia
(VAP)
remains
a
critical
challenge
in
ICU
settings,
often
driven
by
the
biofilm-mediated
bacterial
colonization
of
endotracheal
tubes
(ETTs).
This
study
investigates
antimicrobial
resistance
patterns
and
biofilm
dynamics
patients,
focusing
on
microbial
trends
tracheal
aspirates
tube
biofilms
at
county
emergency
hospital
Romania.
Methods:
We
conducted
longitudinal
analysis
patients
requiring
mechanical
ventilation
for
more
than
48
h.
Tracheal
ETT
were
collected
three
key
time
points:
T1
(baseline),
T2
(48
h
post-intubation
with
replacement),
T3
(92–100
post-T2);
these
analyzed
using
sonication
microbiological
techniques
to
assess
patterns.
Results:
In
total
30
bacteria
from
ESKAPEE
group
(e.g.,
Klebsiella
pneumoniae,
Acinetobacter
baumannii,
Staphylococcus
aureus)
dominated
microbiota,
increasing
their
prevalence
over
time.
Resistance
carbapenems,
colistin,
vancomycin
was
notably
observed,
particularly
among
K.
pneumoniae
A.
baumannii.
Biofilm
revealed
high
persistence
rates
emergence
multidrug-resistant
strains,
underscoring
role
ETTs
as
reservoirs
resistant
pathogens.
The
replacement
correlated
shift
composition
reduced
biofilm-associated
contamination.
Conclusions:
highlights
temporal
evolution
limited
number
(30
patients).
findings
support
implementing
routine
management
strategies,
including
scheduled
replacements
advanced
biofilm-disruption
techniques,
mitigate
VAP
risk
improve
patient
outcomes.
Язык: Английский
Emerging Trends in Fluorescent and Quenching Nanomaterials for Viral detection: Innovations in Biological and Chemical sensing
Talanta Open,
Год журнала:
2025,
Номер
11, С. 100430 - 100430
Опубликована: Март 27, 2025
Язык: Английский
Electrochemical glucose biosensors based on microbial whole cells
Sema Aslan,
Müjgan Kesik Oktay,
Afike Ayça Özen
и другие.
Electrochemistry,
Год журнала:
2024,
Номер
unknown, С. 27 - 67
Опубликована: Ноя. 27, 2024
The
detection
and
measurement
of
biological
analytes
is
greatly
aided
by
the
novel
technology
electrochemical
biosensors
that
employ
entire
microbial
cells.
These
detect
signals
generated
interactions
immobilising
microorganisms
(algae,
fungi,
bacteria,
etc.)
on
electrode
surface.
This
technique
has
a
great
deal
promise
for
use
in
many
different
fields,
especially
biotechnology,
environmental
monitoring,
food
safety,
medical
diagnostics.
chapter
provides
thorough
explanation
how
to
determine
glucose
using
microorganisms.
Язык: Английский
Exploring the Role of Bioenergy in Achieving Sustainable Waste Utilization and Promoting Low-Carbon Transition Strategies
Idoko Peter Idoko,
Jamiu Seun Akindele,
Williams Ugbor Imarenakhue
и другие.
International Journal of Scientific Research in Science and Technology,
Год журнала:
2024,
Номер
11(3), С. 950 - 973
Опубликована: Июнь 20, 2024
The
growing
global
emphasis
on
sustainable
development
and
carbon
neutrality
has
intensified
the
need
for
innovative
waste
utilization
strategies
that
align
with
low-carbon
transition
goals.
This
study
explores
critical
role
of
bioenergy
in
transforming
into
a
valuable
resource
while
promoting
environmental
practices.
research
delves
intersection
technologies,
management,
emission
reduction
strategies,
examining
their
synergistic
potential
to
achieve
circular
economy.
Through
an
in-depth
review
literature,
this
identifies
current
challenges
opportunities
production,
including
its
technical,
economic,
policy
dimensions.
Methodologically,
employs
combination
life
cycle
assessment,
footprint
analysis,
case
studies
evaluate
impact
strategies.
findings
reveal
systems
not
only
reduce
accumulation
but
also
significantly
mitigate
greenhouse
gas
emissions,
contributing
sustainability
However,
such
as
inconsistencies,
technological
barriers,
high
implementation
costs
persist,
hindering
large-scale
adoption.
Based
these
findings,
paper
provides
actionable
recommendations
policymakers,
industry
stakeholders,
researchers,
emphasizing
integration
within
economy
models
adoption
supportive
frameworks.
concludes
represents
transformative
pathway
toward
achieving
future,
offering
scalable
solution
address
fostering
economic
social
resilience.
contributes
discourse
bioenergy's
underscores
cornerstone
Язык: Английский