Near-Infrared Probes Designed with Hemicyanine Fluorophores Featuring Rhodamine and 1,8-Naphthalic Derivatives for Viscosity and HSA Detection in Live Cells

ACS Applied Bio Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 6, 2025

This paper presents the development of near-infrared (NIR) fluorescent probes,

Язык: Английский

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Advances and perspectives in fluorescent probes for imaging hepatopathy-related biomarkers

Coordination Chemistry Reviews, Год журнала: 2023, Номер 497, С. 215407 - 215407

Опубликована: Сен. 12, 2023

Язык: Английский

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Near-Infrared Fluorescent Probe Reveals Elevated Mitochondrial Viscosity during Acute Alcoholic Liver Injury

Analytical Chemistry, Год журнала: 2024, Номер 96(37), С. 14860 - 14866

Опубликована: Сен. 4, 2024

Acute alcoholic liver injury (AALI) has become an important cause of disease worldwide, and there is urgent need to develop noninvasive sensitive methods detect evaluate AALI. We report herein three novel but readily available mitochondrial targeting fluorescence probes (

Язык: Английский

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Recent progress in small molecule fluorescent probes for imaging and diagnosis of non-alcoholic fatty liver disease

Coordination Chemistry Reviews, Год журнала: 2024, Номер 513, С. 215864 - 215864

Опубликована: Май 7, 2024

Язык: Английский

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A turn-on fluorescent probe for detecting and bioimaging of HOCl in inflammatory and liver disease models

Bioorganic Chemistry, Год журнала: 2023, Номер 143, С. 107051 - 107051

Опубликована: Дек. 19, 2023

Язык: Английский

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Mechanistic analysis of viscosity-sensitive fluorescent probes for applications in diabetes detection

Journal of Materials Chemistry B, Год журнала: 2024, Номер 12(12), С. 2917 - 2937

Опубликована: Янв. 1, 2024

This review focuses on fluorescence mechanisms for viscosity responsiveness, highlighting some important probes like coumarin, BODIPY, and xanthene as well the application of these viscosity-sensitive successful diabetes detection.

Язык: Английский

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Rational design of mitochondria-targeted fluorescent biosensors for in vivo elucidation of the interaction between breast cancer metastasis and mitochondrial autophagy

Biosensors and Bioelectronics, Год журнала: 2024, Номер 251, С. 116123 - 116123

Опубликована: Фев. 9, 2024

Язык: Английский

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Design, synthesis and application of polarity- and pH-sensitive dual-responsive small molecule fluorescent probe for early cancer diagnosis

Microchemical Journal, Год журнала: 2024, Номер 205, С. 111250 - 111250

Опубликована: Июль 23, 2024

Язык: Английский

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Dual-State Emissive Mitochondrial Viscosity Probe for Long-Term Imaging of Rheumatoid Arthritis

Analytical Chemistry, Год журнала: 2025, Номер unknown

Опубликована: Янв. 22, 2025

Rheumatoid arthritis (RA) is a destructive autoimmune disease that seriously affects human health. Due to the lack of cure for RA, good prognosis largely depends on early diagnosis and effective treatment monitoring RA. Therefore, development fluorescent probes capable real-time detection RA great significance. Dual-state emission (DSE) molecules can emit light in both dilute solution solid state, making them ideal fluorophores constructing probes. However, there are currently no reports DSE molecule-based imaging. Herein, we report probe MQP-Boc based novel molecule selectively responds viscosity with sensitive fluorescence changes at 667 nm mitochondria targetable. Cell imaging studies show detect mitochondrial perform long-term mitochondria, which significantly superior control MQP-Ac. Imaging mouse model induced by λ-carrageenan has excellent capabilities Besides, MQP-Boc, significant increases joint tissue were found during process. All results indicate an new tool studying diagnosing

Язык: Английский

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A wash-free fluorescent probe with red-emission for monitoring mitochondrial viscosity changes during cellular metabolism and different death processes

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер 333, С. 125884 - 125884

Опубликована: Фев. 10, 2025

Язык: Английский

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