Metal self-reducing triggered green etching for the CuO@Ag composite synthesis and its application in high-sensitive lateral flow immunoassay

Chemical Engineering Journal, Год журнала: 2024, Номер 498, С. 155341 - 155341

Опубликована: Сен. 6, 2024

Язык: Английский

---

Overview of the Design and Application of Photothermal Immunoassays

Sensors, Год журнала: 2024, Номер 24(19), С. 6458 - 6458

Опубликована: Окт. 6, 2024

Developing powerful immunoassays for sensitive and real-time detection of targets has always been a challenging task. Due to their advantages direct readout, controllable sensing, low background interference, photothermal have become type new technology that can be used various applications such as disease diagnosis, environmental monitoring, food safety. By modification with antibodies, materials induce temperature changes by converting light energy into heat, thereby reporting specific target recognition events. This article reviews the design application based on different materials, including noble metal nanomaterials, carbon-based two-dimensional oxide sulfide Prussian blue nanoparticles, small organic molecules, polymers, etc. It pays special attention role working principle immunoassays. Additionally, challenges prospects future development are briefly discussed.

Язык: Английский

---

Ag-coated Au nanostar-Based Lateral Flow Immunoassay for Highly Sensitive Influenza A virus antibody Detection in Colorimetric and Surface-Enhanced Raman Scattering (SERS) modes

Talanta, Год журнала: 2024, Номер 285, С. 127351 - 127351

Опубликована: Дек. 6, 2024

Язык: Английский

---

Multiplexed detection of eight respiratory viruses based on nanozyme colorimetric microfluidic immunoassay

Frontiers in Bioengineering and Biotechnology, Год журнала: 2024, Номер 12

Опубликована: Май 16, 2024

Pandemics caused by respiratory viruses, such as the SARS-CoV-1/2, influenza virus, and syncytial have resulted in serious consequences to humans a large number of deaths. The detection viruses early stages infection can help control diseases preventing spread viruses. However, diversity virus species subtypes, their rapid antigenic mutations, limited viral release during pose challenges detection. This work reports multiplexed microfluidic immunoassay chip for simultaneous eight with noticeable population, namely, A B SARS-CoV-2, human bocavirus, metapneumovirus, adenovirus, parainfluenza nanomaterial nanozyme (Au@Pt nanoparticles) was optimized improve labeling efficiency enhance sensitivity significantly. Nanozyme-binding antibodies were used detect proteins limit 0.1 pg/mL naked eye microplate reader within 40 min. Furthermore, specific screened against conserved each immunoassay, clinical sample showed high specificity without cross reactivity among pathogens. In addition, accuracy, compared RT-PCR assay detection, 97.2%/94.3% positive/negative coincidence rates. proposed approach thus provides convenient, rapid, sensitive method which is meaningful diagnosis infections. Significantly, it be widely pathogens biomarkers replacing only antigen-specific antibodies.

Язык: Английский

---

Entropy-Driven DNA Nanomachine with Magnetic Assistance Manipulating the Aggregation of AU Nanoparticles for Label-Free Photothermal Aptasensing

Опубликована: Янв. 1, 2024

Язык: Английский

---

Entropy-driven DNA nanomachine with magnetic assistance manipulating the aggregation of Au nanoparticles for label-free photothermal Aptasensing

Microchemical Journal, Год журнала: 2024, Номер unknown, С. 111751 - 111751

Опубликована: Сен. 1, 2024

Язык: Английский

---

Nanolabels for biosensors based on lateral flow immunoassays

Analytica Chimica Acta, Год журнала: 2024, Номер 1340, С. 343597 - 343597

Опубликована: Дек. 28, 2024

Язык: Английский

---