Cellulose test strips modified with virus-like particles: Advancing viral immunity screening technologies

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер unknown, С. 125819 - 125819

Опубликована: Янв. 1, 2025

The COVID-19 pandemic has driven immunity acquisition through infection or vaccination, leading to SARS-CoV-2 antibodies. This study introduces a colorimetric biosensor for screening using Virus-Like Particles (VLPs) with spike protein motifs on cellulose carrier. was chemically modified DSS secure the VLPs, verified via FTIR. Detection utilized Bradford reagent, RGB color analysis ImageJ and smartphone images. test strips demonstrated high sensitivity (R > 0.998) across 10-40 µg/mL range in buffer serum, 30-minute incubation. They also exhibited selectivity against interferents like albumin, glucose, urea. Success undiluted samples highlights clinical potential. broad-spectrum, REASSURED-compliant method is promising global testing applications.

Язык: Английский

---

One-pot synthesized three-way junction based multiple strand displacement amplification for sensitive assay of H5N1 DNA

The Analyst, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

One-pot synthesis of three-way junction (TWJ) is proposed. Based on TWJ, strand displacement amplification and Cas12a system, a sensitive assay strategy developed targeting H5N1 DNA.

Язык: Английский

---

Sensitive and Selective Detection of Cancer Biomarkers with Molecularly Imprinted Biosensors

Talanta Open, Год журнала: 2025, Номер unknown, С. 100444 - 100444

Опубликована: Март 1, 2025

Язык: Английский

---