Emergence and spatiotemporal incidence of dengue in Rio Grande do Sul, Brazil
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Май 29, 2025
This
ecological
study
used
surveillance
data
to
examine
the
spatiotemporal
dynamics
of
dengue
in
RS
from
2007
2023.
The
temporal
progression
and
geographic
distribution
cases
were
analyzed
using
generalized
additive
models
(GAM),
Local
Indicators
Spatial
Association
(LISA),
scan
statistics.
During
period,
126,067
142
deaths
reported,
with
80.5%
85.2%
occurring
between
2022
mean
incidence
rate
was
65.3
per
100,000
inhabitants,
mortality
0.11
100,000.
GAM
analysis
demonstrated
a
marked
escalation
risk
beginning
2019,
pronounced
intensification
onward,
indicating
an
ongoing
epidemic.
Most
fatalities
concentrated
Northwest
Rio
Grande
Metropolitan
Porto
Alegre
mesoregions.
Significant
spatial
clusters
detected
Central
Eastern
Western
mesoregions
2021
2023,
encompassing
approximately
2.8
million
individuals.
These
findings
underscore
critical
need
enhance
implement
robust
primary-prevention
measures.
Such
measures
are
vital
for
curbing
current
epidemic
mitigating
future
outbreaks.
provides
detailed
epidemiological
assessment
expansion
RS,
highlighting
priority
areas
intervention
resource
effectively
manage
evolving
public
health
threats.
Язык: Английский
SARS-CoV-2 surveillance in captive animals at the belo horizonte zoo, Minas Gerais, Brazil
Virology Journal,
Год журнала:
2024,
Номер
21(1)
Опубликована: Ноя. 19, 2024
The
pandemic
caused
by
SARS-CoV-2
has
not
only
affected
humans
but
also
raised
concerns
about
its
transmission
to
wild
animals,
potentially
creating
natural
reservoirs.
Understanding
these
dynamics
is
critical
for
preventing
future
pandemics
and
developing
control
strategies.
This
study
aims
investigate
the
presence
of
in
mammals
at
Belo
Horizonte
Zoo
Brazil,
analyzing
virus's
evolution
zoonotic
potential.
was
conducted
Zoo,
Minas
Gerais,
covering
a
diverse
population
mammals.
Oropharyngeal,
rectal,
nasal
swabs
were
collected
from
47
captive
animals
between
November
2021
March
2023.
determined
using
RT-PCR,
positive
samples
sequenced
phylogenetic
analysis.
Consensus
genomes
classified
Pangolin
NextClade
tools,
maximum
likelihood
phylogeny
inferred
IQ-Tree.
Of
tested,
nine
(19.1%)
SARS-CoV-2.
Positive
included
oropharyngeal,
swabs,
with
highest
positivity
rectal
samples.
Three
successfully
sequenced,
revealing
two
variants:
VOC
Alpha
maned
wolf
(Chrysocyon
brachyurus)
fallow
deer
(Dama
dama),
Omicron
western
lowland
gorilla
(Gorilla
gorilla).
Phylogenetic
analysis
indicated
potential
human-to-animal
transmission,
animal
clustering
close
human
same
region.
highlights
various
mammal
species
emphasizing
complexity
interspecies
transmission.
detection
different
variants
suggests
ongoing
viral
adaptation
new
hosts.
Continuous
monitoring
genomic
surveillance
wildlife
are
essential
understanding
outbreaks.
These
findings
underscore
need
integrated
public
health
strategies
that
include
mitigate
risks
posed
emerging
infectious
diseases.
Язык: Английский
Parasitic Protozoa and Other Vector-Borne Pathogens in Captive Mammals from Brazil
Journal of Zoological and Botanical Gardens,
Год журнала:
2024,
Номер
5(4), С. 754 - 773
Опубликована: Дек. 2, 2024
In
captive
environments,
mammals
are
frequently
exposed
to
various
parasitic
protozoa
and
other
vector-borne
pathogens
that
can
impact
both
animal
health
public
health.
Monitoring
these
is
essential
for
welfare
zoonotic
disease
control.
This
study
aimed
investigate
the
prevalence
of
in
through
molecular
detection
methods
at
Belo
Horizonte
Zoo,
Brazil.
Between
November
2021
March
2023,
whole
blood
samples
were
collected
from
40
mammals.
Molecular
analyses
identified
piroplasms,
Leishmania
spp.,
granulocytic/platelet
Anaplasma/Ehrlichia
monocytic
Ehrlichia
Bartonella
spp.
hemotropic
Mycoplasma
with
a
72.5%
positivity
rate.
Piroplasms
found
22.5%
(two
Pantanal
cats,
two
gorillas,
one
white
rhinoceros,
spider
monkey,
jaguar,
tufted
capuchin
hippo)
12.9%
(four
maned
wolves).
Granulocytic/platelet
12.5%
(one
gorilla
four
wolves),
canis
2.5%
animals
wolf),
42.5%
(six
howler
monkeys,
wolves,
gorilla,
rhino,
southern
tamandua,
common
woolly
capuchin,
brown
brocket
deer,
agouti,
cougar
hippo),
17.5%
wolf,
monkeys
European
fallow
deer).
Five
Artiodactyla
members
tested
negative
A.
marginale.
Coinfections
occurred
34.5%
positive
samples.
Sequencing
revealed
Theileria
Cytauxzoon
closely
related
bicornis
felis;
B.
clarridgeiae
henselae;
Candidatus
haemominutum.
Our
results
showed
high
occurrence
animals,
including
species,
which
may
pose
risk
human
Язык: Английский
Coinfection with Leishmania infantum and Toxoplasma gondii in Domestic Cats from a Region with a High Prevalence of Feline Immunodeficiency Virus
Microorganisms,
Год журнала:
2023,
Номер
12(1), С. 71 - 71
Опубликована: Дек. 29, 2023
The
aim
of
this
study
was
to
investigate
the
coinfection
feline
retroviruses
(feline
immunodeficiency
virus—FIV,
and
leukemia
virus—FeLV)
with
Leishmania
infantum
Toxoplasma
gondii
factors
associated
these
pathogens
in
domestic
cats
from
Mossoró,
a
city
endemic
for
canine
human
leishmaniasis
situated
semiarid
region
Northeast
Brazil.
Blood
samples
120
were
collected,
an
epidemiological
questionnaire
applied
risk
infections.
Retroviruses,
L.
infantum,
T.
infections
assessed
using
point-of-care
ELISA
quantitative
PCR
(qPCR),
indirect
fluorescent
antibody
test
(IFAT)
qPCR,
IFAT,
respectively.
overall
seroprevalences
observed
35%
(95%
CI
=
27.0–43.8%)
FIV,
0.8%
0.1–4.5%)
FeLV,
25.8%
18.8–34.3%)
gondii,
4.2%
1.7–9.3%)
infantum.
Coinfection
FIV
2.5%
(3/120)
cats,
while
12.5%
(15/120)
coinfected
gondii.
No
significant
association
found
among
investigated
agents
(p
>
0.05).
infection
multivariable
analysis
male
sex
age
above
78
months.
findings
demonstrated
high
rate
Brazilian
exposure
animals
zoonotic
opportunistic
agents.
Due
immunosuppressive
potential
infected
retrovirus
should
be
screened
coinfections
preventative
measures
adopted.
Язык: Английский
Nyaki tumort utánzó elváltozás egy 13 éves fiúban: post-COVID-bartonellosis
Zoltán Iszlai,
Prince Ottor,
Erika Tóth
и другие.
Orvosi Hetilap,
Год журнала:
2024,
Номер
165(9), С. 351 - 355
Опубликована: Март 3, 2024
Egy
13
éves
fiú
lázzal,
köhögéssel,
szaglásvesztéssel
és
kb.
2
×
3
cm
átmérőjű,
jobb
oldali
nyaki
elváltozással
jelentkezett
hozzátartozójának
kíséretében
kórházunk
gyermekgyógyászati
szakambulanciáján.
A
vizsgálat
előtt
24
nappal
a
dokumentált
nasopharyngealis
COVID–19-gyorstesztje
pozitivitást
mutatott.
Mivel
az
ultrahangvizsgálaton
beolvadási
jeleket
nem
tapasztaltak,
orális
antibiotikumterápiát
(klaritromicin,
500
mg)
javasoltak
7
napig,
szerológiai
vizsgálatokra
vért
vettek.
beteg
nap
elteltével
újból
elváltozás
progresszív
növekedése
miatt.
Osztályunkon
vékonytű-biopszia,
valamint
mellkasi
CT-vizsgálatok
történtek.
citológiai
C3-diagnózissal
zárult
anélkül,
hogy
egyértelműen
kizárta
volna
aspirált
sejtek
rosszindulatú
jellemzőit.
CT
60
46
40
mm-es,
supraclavicularisan
elhelyezkedő
inhomogén
daganatot
írt
le,
intrathoracalis
régió
inváziója
nélkül,
tályogképződés
lehetséges
jeleivel,
azonos
vena
jugularis
kompresszióval.
Idővel
Bartonella
henselae
képlet
műtéti
eltávolítása
mellett
döntöttünk.
Szövettani
vizsgálattal
nekrotizáló
granulomák
voltak
kimutathatók
atípusos
jelenléte
nélkül.
Ezek
eredmény
alapján
bartonellosis
diagnózisát
állítottuk
fel.
Bár
SARS-CoV-2-fertőzés
hatásáról
klinikai
lefolyására
irodalomban
találtunk
adatot,
esetünk
kapcsán
elképzelhetőnek
tartjuk,
COVID–19
által
legyengített
szervezetben
bakteriális
fertőzés
egyébként
ártalmatlan
betegség
helyett
súlyosabb
képét
okozta,
melynek
megoldását
gyógyszeres
kezelésre
nehezen
reagáló
teljes
jelentette.
Orv
Hetil.
2024;
165(9):
351–355.