Regulating ice formation for enhancing frozen food quality: Materials, mechanisms and challenges

Trends in Food Science & Technology, Год журнала: 2023, Номер 139, С. 104116 - 104116

Опубликована: Июль 23, 2023

Freezing reduces the temperature of food system and extends shelf life food. However, inevitable formation ice crystals could impact quality. Small-size are more acceptable in frozen foods than large aggregates with irregular shapes. Undesired not only change structure cause serious quality deterioration, including texture alteration, nutrient loss off-flavour. Ice-regulating materials have been proven to regulate nucleation, growth recrystallization, which show promising applications industry. The theoretical information on formation, particularly nucleation was described. Current ice-regulating materials, such as active proteins, saccharides, natural deep eutectic solvents (NADES), their mechanisms regulating were summarized. Based damage foodstuffs different microstructures, improving also discussed. showed superior actions addition alleviated improved by accelerating or inhibiting freezing. Moreover, current challenges future perspectives regulation for high-efficiency freezing proposed.

Язык: Английский

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Fabricating biomimetic materials with ice‐templating for biomedical applications

Smart Medicine, Год журнала: 2023, Номер 2(3)

Опубликована: Июль 5, 2023

The proper organization of cells and tissues is essential for their functionalization in living organisms. To create materials that mimic natural structures, researchers have developed techniques such as patterning, templating, printing. Although these own several advantages, processes still involve complexity, are time-consuming, high cost. better simulate with micro/nanostructures evolved millions years, the use ice templates has emerged a promising method producing biomimetic more efficiently. This article explores historical approaches taken to produce traditional structural biomaterials delves into principles underlying ice-template various applications creation materials. It also discusses most recent biomedical uses created via templates, including porous microcarriers, tissue engineering scaffolds, smart Finally, challenges potential current technology analyzed.

Язык: Английский

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Cryopreservation in the Era of Cell Therapy: Revisiting Fundamental Concepts to Enable Future Technologies

Advanced Functional Materials, Год журнала: 2023, Номер 33(40)

Опубликована: Июнь 3, 2023

Abstract Cryopreservation strives to maximize the viability and biofunctionality of cells tissues by cooling them a subzero temperature facilitate storage delivery. This technology has enabled clinics labs preserve rare crucial samples is poised become more important with rising interest in cell therapy. Here, biological impact rates on different cellular components first described, paying special emphasis differences between slow vitrification heat transfer perspective based Biot number. followed an overview various classes chemical‐based cryoprotective agents including small molecules, antifreeze proteins, hydrogels, nanomaterials. Most importantly, fundamental concepts cryopreservation Mazur's “two‐factor hypothesis” are revisited, gaps highlighted, experiments validate reported claims deepen mechanistic understanding cryoprotection proposed. A matric also introduced assess suitability biomaterials for use therapy support manufacturers making strategic choices storing clinical samples. It believed that this review would inspire readers scrutinize development new materials technologies emerging manufacturing industry.

Язык: Английский

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Modeling the freezing process of aqueous solutions considering thermal gradients and stochastic ice nucleation

Chemical Engineering Journal, Год журнала: 2024, Номер 483, С. 148660 - 148660

Опубликована: Янв. 9, 2024

Despite its importance to multiple scientific fields and industries, the freezing process of aqueous solutions is not yet completely understood. In particular, relationship between temperature gradients within a solution occurrence stochastic ice nucleation remains elusive. To address this knowledge gap, we have derived novel spatial model from first principles. The predicts with quantitative accuracy how affect sucrose in vials. This motivated detailed study freezing-stage freeze-drying, revealing that broad range temperatures are present at time different positions vial. must be considered when interpreting experimental studies measure only single point thermocouple. ensure both researchers practitioners benefit modeling work, provide open source access it our python package ethz-snow.

Язык: Английский

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Numerical Modeling of Ice Crystal Dendritic Growth with Humidity by Using an Anisotropic Phase Field Model

Crystal Growth & Design, Год журнала: 2024, Номер 24(3), С. 1400 - 1409

Опубликована: Янв. 17, 2024

To study the growth characteristics of ice crystals under different humidities, equation for subcooling coefficient is fitted, and a phase-field method model based on heat mass transfer energy conservation established. The effects humidity, dimensionless latent heat, anisotropic strength are analyzed. results show that radius dendrites increases continuously when relative humidity from 55% to 80%, which 128% calculated conditions this study. With increase required dendritic crystal crystallization hindrance becomes larger. crystals, increased with became smaller increasing K, decreasing by ∼56.6%. width main decreases in humidity. strength, direction lateral branches more anisotropic, protrusions as increases.

Язык: Английский

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Research progress of freezing processes and devices for fresh meat products

International Journal of Refrigeration, Год журнала: 2024, Номер 161, С. 71 - 82

Опубликована: Фев. 18, 2024

Язык: Английский

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A Close Cognition of Charged Poly(l-methionine) Derivatives for Antifreeze

Langmuir, Год журнала: 2025, Номер unknown

Опубликована: Янв. 7, 2025

Ice formation poses a significant challenge across various fields, from industrial processes to biological preservation. Developing antifreeze agents and recognizing the mechanism have gained considerable attention. Herein, series of poly(l-methionine) derivatives, poly(S-carboxymethyl-l-methionine sulfonium) (PMetA), poly(S-methyl-l-methionine sulfonium chloride) (PMetM), poly(S-carbamidomethyl-l-methionine (PMetAM), with carboxyl, methyl, acetamide groups, respectively, are synthesized investigated for antifreeze. The relationship between polymer structure ice recrystallization inhibition (IRI) activity is examined, suggesting that zwitterionic PMetA shows highest IRI activity, about 27.0 ± 3.9% at 10 mg mL–1 relative water. Results low-field nuclear magnetic resonance differential scanning calorimetry indicate associated activation energy hydrogen bond breakage. exhibits acceptable cytocompatibility 10.0 good cryoprotective efficiency. This finding provides valuable insight into mechanism, contributing development potent cryoprotectants.

Язык: Английский

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Expanding the cryoprotectant toolbox in biomedicine by multifunctional antifreeze peptides

Biotechnology Advances, Год журнала: 2025, Номер unknown, С. 108545 - 108545

Опубликована: Фев. 1, 2025

Язык: Английский

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Coexisting with Ice Crystals: Cryogenic Preservation of Muscle Food─Mechanisms, Challenges, and Cutting-Edge Strategies

Journal of Agricultural and Food Chemistry, Год журнала: 2023, Номер 71(49), С. 19221 - 19239

Опубликована: Ноя. 10, 2023

Cryopreservation, one of the most effective preservation methods, is essential for maintaining safety and quality food. However, there no denying fact that muscle food deteriorates as a result unavoidable production ice. Advancements in cryoregulatory materials techniques have effectively mitigated adverse impacts ice, thereby enhancing standard freezing preservation. The first part this overview explains how ice forms, including theoretical foundations nucleation, growth, recrystallization well key influencing factors affect each process. Subsequently, impact formation on eating nutritional value delineated. A systematic explanation cutting-edge strategies based nucleation intervention, growth control, inhibition offered. These methods include antifreeze proteins, ice-nucleating peptides, natural deep eutectic solvents, polysaccharides, amino acids, their derivatives. Furthermore, advanced physical such electrostatic fields, magnetic acoustic liquid nitrogen, supercooling are expounded upon, which hinder crystals during cryopreservation. paper outlines difficulties potential directions

Язык: Английский

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Fabrication of controlled porous and ultrafast dissolution porous microneedles by organic-solvent-free ice templating method

International Journal of Pharmaceutics, Год журнала: 2024, Номер 660, С. 124220 - 124220

Опубликована: Май 9, 2024

Язык: Английский

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