
Deleted Journal, Год журнала: 2024, Номер unknown, С. 200171 - 200171
Опубликована: Окт. 1, 2024
Язык: Английский
Deleted Journal, Год журнала: 2024, Номер unknown, С. 200171 - 200171
Опубликована: Окт. 1, 2024
Язык: Английский
Applied Physics Reviews, Год журнала: 2025, Номер 12(1)
Опубликована: Фев. 27, 2025
Along with the ever expanding frontiers of photonic applications as world is fast advancing into information era, there a growing market for specialty waveguides and fibers requiring sophisticated structures materials that conventional manufacturing technologies meet great challenges difficulties to accommodate. Advanced 3D printing or additive possesses flexibility in structure diversity material emerging an essential alternative developing novel waveguides, fibers, devices new applications. This paper reviews printing-based their terms basic processing techniques, fundamental principles mechanisms, current research development, remaining technical problems challenges.
Язык: Английский
Процитировано
0Materials, Год журнала: 2025, Номер 18(7), С. 1580 - 1580
Опубликована: Март 31, 2025
Fungal infections pose a significant global health problem, affecting 20–25% of the population and contributing to over 3.75 million deaths annually. Clotrimazole (CLO) is widely used topical antifungal drug, but its efficacy limited by poor penetration through stratum corneum. Microneedle (MN) systems, composed micron-scale structures arranged on patch, offer promising strategy overcome outermost skin barrier enhance drug into deeper layers. However, optimizing MN design, particularly in terms size, shape, fabrication technology, essential for efficient delivery. This study aimed develop CLO-coated systems using an Liquid Crystal Display (LCD)-based 3D printing technique thin-film dip-coating method. A comprehensive optimization parameters, including anti-aliasing, layer thickness, curing time, angle, was conducted ensure desired mechanical properties. The optimized MNs were coated with either suspension or ethanol-based CLO-hydrogels, ethanol hydrogel demonstrating superior characteristics. Additionally, investigated how microneedle geometry coating formulation influenced release. Antifungal activity against reference clinical origin Candida albicans strains varied significantly depending formulation. Finally, acute toxicity test confirmed no toxic effects Aliivibrio fischeri, indicating potential biocompatibility safety developed MN-based delivery system.
Язык: Английский
Процитировано
0Additive manufacturing, Год журнала: 2025, Номер unknown, С. 104781 - 104781
Опубликована: Апрель 1, 2025
Язык: Английский
Процитировано
0Deleted Journal, Год журнала: 2024, Номер unknown, С. 200171 - 200171
Опубликована: Окт. 1, 2024
Язык: Английский
Процитировано
0