Considerations for mRNA Product Development, Regulation and Deployment Across the Lifecycle

Vaccines, Год журнала: 2025, Номер 13(5), С. 473 - 473

Опубликована: Апрель 28, 2025

With the successful deployment of several mRNA vaccines against SARS-CoV-2, an vaccine RSV (respiratory syncytial virus) and a large pipeline products other infectious diseases, cancers rare it is important to examine whole product lifecycle. technology enables design, testing manufacturing systems be rapidly developed, but these advantages can lost if factors that determine public access are not closely considered. This review analyzes key aspects lifecycle including candidate manufacturing, quality safety storage. Regulatory thinking well advanced in some countries others, more thought on regulation outside pandemic situation as therapeutics individual neoantigen therapies disease treatments needed. Consumer acceptance-the "social license operate" around products-is critical for their uptake, particularly pandemic.

Язык: Английский

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mRNA Vaccines

Опубликована: Янв. 1, 2025

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Unlock the sustained therapeutic efficacy of mRNA

Journal of Controlled Release, Год журнала: 2025, Номер unknown, С. 113837 - 113837

Опубликована: Май 1, 2025

Язык: Английский

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Exploring the potential of oligonucleotide mapping with liquid chromatography – mass spectrometry to study the primary structure of mRNA

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118309 - 118309

Опубликована: Май 1, 2025

Язык: Английский

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Lipid nanoparticles driving mRNA vaccine innovations: From concept to clinic

Applied Materials Today, Год журнала: 2025, Номер 44, С. 102786 - 102786

Опубликована: Май 19, 2025

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