Myopia in Children: Epidemiology, Genetics, and Emerging Therapies for Treatment and Prevention
Children,
Год журнала:
2024,
Номер
11(12), С. 1446 - 1446
Опубликована: Ноя. 27, 2024
Refractive
errors,
particularly
myopia,
are
among
the
most
prevalent
visual
impairments
globally,
with
rising
incidence
in
children
and
adolescents.
This
review
explores
epidemiology
risk
factors
associated
development
of
refractive
focusing
on
environmental
lifestyle
contributing
to
current
surge
myopia.
We
provide
an
overview
key
genetic
molecular
pathways
driving
pathogenesis
myopia
other
emphasizing
complex
interplay
between
predisposition
triggers.
Understanding
underlying
mechanisms
is
crucial
for
identifying
new
strategies
intervention.
discuss
approaches
slow
progression
pediatric
populations,
including
pharmacological
treatment
regimens
(low-dose
atropine),
optical
interventions,
modifications.
In
addition
established
therapies,
we
highlight
emerging
innovations,
agents
advanced
devices,
insights
into
potential
future
treatments.
Cutting-edge
research
gene
therapy,
inhibitors,
neuroprotective
may
yield
novel
therapeutic
targets
that
address
root
causes
errors.
comprehensive
underscores
importance
early
intervention
highlights
promising
avenues
research,
aiming
pediatricians
guidance
ultimately
improve
clinical
outcomes
managing
preventing
young
adults.
Язык: Английский
Effectiveness of Low-Level Red Light in Controlling Myopia Progression in Children: A Systematic Review and Meta-Analysis
Yazeed Bader Alaql,
Saleh A Alkhalaf,
Bader A Almuqaythil
и другие.
Cureus,
Год журнала:
2025,
Номер
unknown
Опубликована: Март 10, 2025
This
study
aimed
to
evaluate
the
effectiveness
of
low-level
red
light
(LLRL)
therapy
compared
single-vision
spectacles
(SVS)
in
controlling
myopia
progression,
focusing
on
spherical
equivalent
refraction
(SER),
axial
length
(AL),
and
subfoveal
choroidal
thickness
(SFCT).
A
comprehensive
search
was
conducted
across
PubMed,
Cochrane
Library,
ScienceDirect,
Web
Science,
including
only
randomized
controlled
trials
(RCTs)
involving
myopic
patients
aged
16
years
or
younger.
Mean
differences
were
calculated
with
95%
CIs,
I²
statistic
used
assess
heterogeneity
among
studies.
The
meta-analysis
included
11
RCTs.
At
three
months,
significant
observed
between
LLRL
SVS
SER
(estimate:
0.225;
CI:
0.042,
0.408;
p
=
0.016)
AL
-0.137;
-0.280,
0.007;
0.062).
six
noted
0.450;
0.351,
0.550;
<
0.001),
-0.179;
-0.278,
-0.079;
SFCT
35.281;
23.230,
47.331;
0.001).
By
12
remained
for
0.806;
0.675,
0.937;
0.001)
-0.294;
-0.416,
-0.172;
These
findings
suggest
that
effectively
reduces
progression
children,
as
indicated
by
improvements
SER,
slower
growth,
stabilization
slight
increases
SFCT.
However,
further
studies
are
necessary
determine
optimal
dosage,
long-term
safety,
overall
efficacy
therapy.
Язык: Английский
Prevalence and Associated Factors of Myopia among University Students in Mogadishu, Somalia
Dahir Adan Ali,
Said Abdirahman Adan,
Mohamed Hassan Mohamed Gafow
и другие.
Open Journal of Epidemiology,
Год журнала:
2025,
Номер
15(02), С. 296 - 320
Опубликована: Янв. 1, 2025
Язык: Английский
Association Between Myopia and Dental Caries of 385844 School-Aged Children and Adolescents in China: A large scale Cross-Sectional Study
Research Square (Research Square),
Год журнала:
2025,
Номер
unknown
Опубликована: Май 9, 2025
Abstract
Background:
Prevalence
of
dental
caries
is
increasing
among
children
and
adolescents,
which
can
delay
growth
development.
This
study
aimed
to
determine
the
association
between
severity
myopia
in
a
large-scale
school-based
population
China.
Methods:
The
data
from
School-Based
Chinese
Adolescents
Health
Survey
(SCAHS)
were
collected
for
all
adolescents
aged
6
18
years
students
Zhejiang
Province
China
2020
2023.
Multinomial
logistic
regression
models
used
estimate
myopia.
Results:
All
with
severe
primary
school
(OR
=
0.72,
95%
CI:
0.50-0.94),
middle
0.86,
0.79-0.94),
high
0.80,
0.67-0.95)
less
likely
have
compared
those
no
after
adjusting
age,
gender,
family
structure,
academic
pressure,
regional
classification,
economic
level,
environmental
support,
frequency
eating
sweets,
fried
foods,
alcohol
consumption,
smoking
status,
internet
usage
time,
sleep
duration,
weight
parental
myopia,
outdoor
activity
eye
habits.
Conclusion:
Our
found
significant
inverse
relationship
chinese
students,
strength
varying
across
different
educational
stages.
These
results
highlight
potential
integrated
public
health
interventions
targeting
low
levels
but
at
risk
Язык: Английский
Prediction of Myopia Among Undergraduate Students Using Ensemble Machine Learning Techniques
Health Science Reports,
Год журнала:
2025,
Номер
8(5)
Опубликована: Май 1, 2025
ABSTRACT
Background
and
Aims
Myopia
is
a
prevalent
refractive
error,
particularly
among
young
adults,
becoming
growing
global
concern.
This
study
aims
to
predict
myopia
undergraduate
students
using
ensemble
machine
learning
techniques
identify
key
risk
factors
associated
with
its
development.
Methods
A
cross‐sectional
was
conducted
in
Dinajpur
city,
collecting
514
samples
through
self‐structured
questionnaire
covering
demographic
information,
prevalence
factors,
knowledge
attitudes,
daily
activities.
Four
feature
selection
Boruta‐based
(BFS),
Least
Absolute
Shrinkage
Selection
Operator
regression,
Forward
Backward
Random
Forest
(RF)
identified
12
predictive
features.
Using
these
features,
methods,
including
logistic
regression
artificial
neural
network,
RF,
Support
Vector
Machine,
extreme
gradient
boosting,
light
boosting
were
employed
for
prediction.
Model
performance
evaluated
accuracy,
precision,
recall,
F1‐score,
area
under
the
curve
(AUC).
Results
The
stacking
model
achieved
highest
performance,
an
accuracy
of
95.42%,
recall
93.42%,
precision
98.85%,
F1‐score
96.08%,
AUC
0.979.
SHapley
Additive
exPlanations
analysis
visual
impairment,
family
history
myopia,
excessive
screen
time,
insufficient
outdoor
Conclusion
These
findings
demonstrate
effectiveness
predicting
highlight
potential
early
intervention
strategies.
By
identifying
high‐risk
individuals,
targeted
awareness
programs
lifestyle
modifications
can
help
mitigate
progression
students.
Язык: Английский
Expanding Horizons: AJO goes International
Deleted Journal,
Год журнала:
2024,
Номер
1(1), С. 100019 - 100019
Опубликована: Апрель 1, 2024
Язык: Английский
Uptake of Myopia Control Strategies and Its Demographic Profile amongst Teenagers and Eyecare Practitioners of Lurambi Constituency, Kenya
African Journal of Empirical Research,
Год журнала:
2024,
Номер
5(3), С. 1024 - 1035
Опубликована: Сен. 9, 2024
The
growing
prevalence
of
myopia
has
become
a
public
health
concern.
As
2020,
affected
2.6
billion
individuals
globally,
and
it
is
projected
that
by
2050,
almost
half
the
world's
population
will
be
myopia.
Therefore,
there
need
for
sensitization
populations
on
available
strategies
proper
utilization
these
to
reduce
its
progression.
study
employed
an
analytical
cross-sectional
research
design.
Eye
clinics
in
Lurambi
Constituency
participants
at
clinic
level
were
selected
purposefully,
whereas
all
teenagers
eyecare
practitioners
(ECPs)
enrolled
census.
A
self-administered
questionnaire,
containing
questions
demographic
profile
ECPs,
was
used
collect
data.
Once
ethical
clearance
from
MMUST
IERC,
NACOSTI,
permission
eye
obtained,
data
collection
process
began.
total
115
22
ECPs
participated
study.
uptake
control
among
55.7%,
while
effective
reported
86.36%,
with
single
vision
spectacles
being
most
70.3%
teenagers.
Among
teenagers,
higher
males
51.6%,
those
attending
73.9%,
aged
19
years
42.2%,
upper
secondary
51.7%.
greatest
male
73.7%,
18-30
less
than
5
experience
40.9%,
optometry
technologists
optometrists
36.8%
each.
Uptake
equally
distributed
between
private
50%
relatively
high.
high
both
ECPs.
MCS
should
conducted,
covering
larger
Kenya.
Язык: Английский