Special Issue on “Ketamine, MDMA, and Psychedelics in the Treatment of Neuropsychiatric Disorders”

Asian Journal of Psychiatry, Год журнала: 2025, Номер 106, С. 104426 - 104426

Опубликована: Март 5, 2025

Язык: Английский

Applications of MDMA in Modern Medicine - A Literature Review

Journal of Education Health and Sport, Год журнала: 2025, Номер 77, С. 56620 - 56620

Опубликована: Янв. 14, 2025

MDMA or 3,4- methylenedioxymethamphetamine is a psychoactive substance, exhibiting mild hallucinogenic properties, that became widely known as recreational party drug. However, its ability in helping individuals access deeply rooted emotions has prompted significant interest potential applications within clinical practice. MDMA’s mechanism of action involves increasing the release serotonin, dopamine and oxytocin. This process enhances neuroplasticity, fosters empathy aids trauma processing fear extinction. study aims to explore uses medicine, particularly treating mental illnesses. The article was developed using data from „PubMed” „Google Scholar” databases, with particular emphasis on articles published after 2021. When combined psychotherapy, offers therapeutic benefits, especially for patients resistant conventional treatments. Existing research primarily highlights effectiveness managing post traumatic stress disorder (PTSD) anxiety disorders, emerging evidence suggesting benefits conditions like depression eating disorder. While use poses risks, controlled environment demonstrates favourable safety profile. Despite highly promising results MDMA- assisted therapy so far, additional crucial enable this drug revolutionise future treatment methods.

Язык: Английский

Subdiaphragmatic vagotomy reduces hypothalamic oxytocin expression and blood levels after oral MDMA administration in male rats

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Год журнала: 2025, Номер 137, С. 111260 - 111260

Опубликована: Янв. 22, 2025

Язык: Английский