BMJ Open Respiratory Research,
Год журнала:
2025,
Номер
12(1), С. e002528 - e002528
Опубликована: Янв. 1, 2025
Background
An
estimated
10–30%
of
people
with
COVID-19
experience
debilitating
long-term
symptoms
or
long
covid.
Underlying
health
conditions
associated
chronic
inflammation
may
increase
the
risk
Methods
We
conducted
a
systematic
review
and
meta-analysis
to
examine
whether
covid
was
altered
by
pre-existing
asthma
obstructive
pulmonary
disease
(COPD)
in
adults.
identified
studies
searching
PubMed
Embase
databases
from
inception
13
September
2024.
excluded
that
focused
on
children
defined
only
terms
respiratory
symptoms.
used
random-effects,
restricted
maximum
likelihood
models
analyse
data
pooled
51
studies,
which
included
43
analyses
30
COPD.
The
bias
assessed
using
ROBINS-E
table.
Results
found
41%
increased
odds
(95%
CI
1.29
1.54);
COPD
32%
1.16
1.51).
Pre-existing
asthma,
but
not
COPD,
covid-associated
fatigue.
observed
heterogeneity
results
related
hospitalisation
status.
Potential
confounding
inconsistent
measurement
exposure
outcome
variables
were
among
limitations.
Conclusions
Our
findings
support
hypothesis
covid,
including
fatigue
outcomes
patients
asthma.
Because
targets
tract,
these
inflammatory
lower
tract
could
provide
mechanistic
clues
common
pathway
for
development
sequelae
Journal of Asthma,
Год журнала:
2024,
Номер
61(7), С. 736 - 744
Опубликована: Янв. 8, 2024
The
purpose
of
this
study
was
to
assess:
(1)
the
prevalence
long
COVID
by
asthma
status,
and
(2)
characteristics
associated
with
developing
among
adults
in
United
States.
Journal of Evaluation in Clinical Practice,
Год журнала:
2025,
Номер
31(1)
Опубликована: Фев. 1, 2025
The
positive
effects
of
vaccination
status
on
the
course
Long
COVID
symptoms
have
not
been
fully
elucidated.
Our
aim
is
to
determine
most
common
in
patients
monitored
COVID-19
follow-up
clinic
and
examine
whether
there
a
difference
between
recovery
rates
those
who
are
vaccinated
vaccinated.
Between
December
1,
2020
April
30,
2022,
prospectively
collected
data
916
were
admitted
outpatient
tertiary
hospital
for
first
time
evaluated
as
retrospective
cohort
this
study.
frequencies
ten
last
examinations
478
with
determined,
their
was
compared.
Patients
divided
into
two
groups
according
status.
values
showing
obtained
these
compared
themselves
again.
average
age
study
group
54.43
±
11.71
years,
255
(53.3%)
male.
median
period
10
months.
84.7%
had
received
at
least
one
dose
vaccine.
Statistically
significant
results
found
improvement
all
never-vaccinated
group.
There
no
statistically
CoronaVac,
BNT162b2,
heterologous
(CoronaVac+
BNT162b2)
vaccine
groups.
Factors
affecting
three
(dyspnea,
fatigue,
forgetfulness)
examined
univariate
logistic
regression
analysis,
only
or
non-vaccination
be
risk
factor.
This
showed
that
receiving
may
effective
improving
symptoms.
Although
differences
inactive
mRNA
terms
reducing
symptoms,
higher
detected
BNT162b2.
Journal of Brown Hospital Medicine,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 1, 2025
The
coronavirus
disease
(COVID-19)
pandemic
was
a
global
health
crisis
with
far-reaching
consequences.
Among
these
were
physical
and
mental
complications
that
emerged
weeks
or
even
months
after
the
initial
COVID-19
infection,
collectively
termed
“long
COVID”
“post-COVID
syndrome.”
Identifying
epidemiology,
risk
factors,
clinical
manifestations,
management
strategies
for
long
COVID
is
crucial
both
clinicians
patients,
which
focus
of
this
review.
prevalence
varies
across
studies,
generally
ranging
from
5%
to
20%.
Prominent
factors
include
female
sex,
older
age,
high
number
acute
symptoms,
lower
socioeconomic
status,
underlying
comorbidities
such
as
diabetes,
asthma,
chronic
obstructive
pulmonary
disease.
manifestations
are
diverse;
beyond
commonly
reported
symptoms
fatigue,
malaise,
ageusia,
anosmia,
neuropsychiatric
headache,
cognitive
deficits,
depression
also
potential
outcomes.
Although
there
currently
no
consensus
on
COVID,
multidisciplinary
care
teams
appropriate
referrals
follow-up
diagnostic
studies
essential
in
evaluating
course
patients.
Depression and Anxiety,
Год журнала:
2025,
Номер
2025(1)
Опубликована: Янв. 1, 2025
Background:
Long‐COVID
has
attracted
increased
attention
with
rising
numbers
of
affected
patients
and
high
individual
symptom
burden.
Prior
studies
have
described
its
prevalence,
course
disease,
severity.
Yet,
the
influence
intensive
care,
including
telemedical
support
for
at
risk
a
severe
initial
COVID‐19
on
occurrence
associated
symptoms
is
studied
to
lesser
extent.
Methods:
Here,
we
report
long‐term
results
COVID‐SMART
study,
which
randomized
at‐risk
either
smartwatch‐based
monitoring
or
standard
care.
We
investigate
symptoms,
depression
anxiety
after
12
months.
Findings:
Between
October
2020
May
2022,
enrolled
607
in
study.
Complete
12‐month
follow‐up
was
available
573
patients,
288
intervention
group
285
control
group.
Overall,
234
participants
(40.8%)
reported
COVID‐related
prevalence
(209
participants,
36.5%)
(232
40.5%).
However,
did
not
reduce
these
follow‐up.
Multivariable
regression
analysis
identified
sex,
active
smoking,
pre‐existing
asthma
as
significant
predictors
both
outcomes.
Interpretation:
first
prospective,
clinical
trial
systematically
assess
impact
care
development
anxiety.
identify
part
modifiable
factors
does
appear
be
beneficial
reducing
should
hence
focused
acute
infection
phase.
Trial
Registration:
ClinicalTrials.gov
identifier:
NCT04471636
Reproductive Biology and Endocrinology,
Год журнала:
2024,
Номер
22(1)
Опубликована: Июнь 7, 2024
Abstract
Fatigue,
an
increasingly
acknowledged
symptom
in
various
chronic
diseases,
has
garnered
heightened
attention,
during
the
medical
era
of
bio-psycho-social
model.
Its
persistence
not
only
significantly
compromises
individual’s
quality
life
but
also
correlates
with
organ
damage.
Surprisingly,
intricate
relationship
between
fatigue
and
female
reproductive
health,
specifically
infertility,
remains
largely
unexplored.
Our
exploration
into
existing
body
evidence
establishes
a
compelling
link
uterine
ovarian
as
well
conditions
associated
such
rheumatism.
This
observation
suggests
potentially
pivotal
role
influencing
overall
fertility.
Furthermore,
we
propose
hypothetical
mechanism
elucidating
impact
on
infertility
from
multiple
perspectives,
postulating
that
neuroendocrine,
neurotransmitter,
inflammatory
immune,
mitochondrial
dysfunction
resulting
its
co-factors
may
further
contribute
to
endocrine
disorders,
menstrual
irregularities,
sexual
dysfunction,
ultimately
leading
infertility.
In
addition
providing
this
comprehensive
theoretical
framework,
summarize
anti-fatigue
strategies
accentuate
current
knowledge
gaps.
By
doing
so,
our
aim
is
offer
novel
insights,
stimulate
research,
advance
understanding
crucial
interplay
health.
