BCL-2 and BAX expression and Germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat DOI Creative Commons
Sunday Aderemi Adelakun,

Olalekan Wasiu Akintunde,

Babatunde Ogunlade

и другие.

Aspects of Molecular Medicine, Год журнала: 2024, Номер unknown, С. 100055 - 100055

Опубликована: Окт. 1, 2024

Язык: Английский

Hepatoprotective activity of Taraxacum officinale extract against CCl4-induced Liver injury in rats DOI

Nesrein S. Salim,

Mohamed F. Abo El‐Maati, Sameh A. Abdelnour

и другие.

Food Bioscience, Год журнала: 2025, Номер unknown, С. 106708 - 106708

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

1

Excessive caffeine intake inhibits steroidogenesis, folliculogenesis and disrupts utero-ovarian tissue histomorphology integrity in experimental rats, and precipitates polycystic ovary syndrome in Sprague-Dawley rats DOI Creative Commons
Sunday Aderemi Adelakun, Babatunde Ogunlade,

Julius Akomaye Aniah

и другие.

Food Chemistry Advances, Год журнала: 2024, Номер 4, С. 100678 - 100678

Опубликована: Март 16, 2024

Polycystic ovarian syndrome (PCOS) is characterized by anovulation and hyperandrogenism symptoms. Caffeine popularly consumed it a legal psychoactive substance. This study evaluated the effect of excessive caffeine intake on utero-ovarian tissue in polycystic ovary rats. Twenty-four female rats randomized into group A control received 2 ml normal saline. Group B 4 mg/kg body weight (bwt) i.p estradiol valerate (EV) first day, C 100 bwt orally, D EV orally. The experiment lasted 30 days. Histology uterus, oxidative antioxidant, reproductive hormone, lipid profile, inflammatory markers, apoptosis markers were evaluated. histoarchitecture revealed degeneration theca cells, granulosa, corpus luteum, loss mucin granules uterine tissues PCOS, CAF, PCO+CAF. estrous cycle became irregular, with prolonged diestrous proestrus phases. Marked rise decline activities enzymatic antioxidants, response, caspase-dependent apoptosis, hormonal imbalance. Excessive consumption, therefore impaired integrity, hormones, indicators, oxidant antioxidant parameters, apoptotic cycle.

Язык: Английский

Процитировано

4

Neurotherapeutic potential of sinapic acid in cerebellar neurotoxicity induced following excessive exposure to tramadol hydrochloride in male Sprague Dawley rats DOI Creative Commons
Sunday Aderemi Adelakun,

Ogunlade Babatunde,

Kingsley Afoke Iteire

и другие.

Deleted Journal, Год журнала: 2025, Номер unknown, С. 200217 - 200217

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0

Computational insights into the anti-diabetic potential of Albizia antunesiana (Mimosaceae) metabolites: A molecular docking, drug-likeness and ADMET analysis DOI Creative Commons
Bitwell Chibuye, Indra Sen Singh, Luke Chimuka

и другие.

Results in Chemistry, Год журнала: 2025, Номер unknown, С. 102422 - 102422

Опубликована: Июнь 1, 2025

Язык: Английский

Процитировано

0

Metformin and vitamin D combination therapy ameliorates type 2 diabetes mellitus-induced renal injury in male Wistar rats DOI
Halimat Amin Abdulrahim, Adeyemi Fatai Odetayo,

Emmanuel Aduragbemi Owootori

и другие.

Naunyn-Schmiedeberg s Archives of Pharmacology, Год журнала: 2024, Номер unknown

Опубликована: Сен. 30, 2024

Язык: Английский

Процитировано

1

Neuroprotective mechanisms and ameliorative activities of quercetin in cisplatin-induced cerebellum neurotoxicity in rat models DOI Creative Commons
Sunday Aderemi Adelakun, Babatunde Ogunlade,

Julius Akomaye Aniah

и другие.

Brain Disorders, Год журнала: 2024, Номер unknown, С. 100166 - 100166

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

1

BCL-2 and BAX expression and Germ cell apoptosis following the intervention of 1-isothiocyanato-4-methylsulfinylbutane in cisplatin-induced testicular toxicity and sperm DNA fragmentation in Sprague-Dawley rat DOI Creative Commons
Sunday Aderemi Adelakun,

Olalekan Wasiu Akintunde,

Babatunde Ogunlade

и другие.

Aspects of Molecular Medicine, Год журнала: 2024, Номер unknown, С. 100055 - 100055

Опубликована: Окт. 1, 2024

Язык: Английский

Процитировано

1